Patents by Inventor Rajesh Dilip Joshi

Rajesh Dilip Joshi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • One pot process for preparing 2-butyl-3-[[2?-(1H-tetrazol-5-yl)[1,1?-biphenyl]-4-yl]methyl]-1,3-diazaspiro [4, 4] non-1-en-4-one (irbesartan)
    Patent number: 8609859
    Abstract: A one pot process for the synthesis of Irbesartan comprising reacting 2-n-Butyl-1,3-Diazaspiro[4,4]Non-1-en-4-one (Formula III) and Bromomethyl Cyanobiphenyl (Formula IV) in the presence of base and water with the optional use of PTC to give formula II from which Irbesartan is obtained by reacting with sodium azide and triethylamine hydrochloride in the presence of a non polar solvent.
    Type: Grant
    Filed: November 19, 2009
    Date of Patent: December 17, 2013
    Assignee: CTX Life Sciences Pvt. Ltd.
    Inventors: Prakash Yashwant Kolhe, Rajesh Dilip Joshi, Bimal Kumar Srivastava, Nitin Jerambhai Patel, Sanket Sureshbhai Gajjar
  • ONE POT PROCESS FOR PREPARING 2-BUTYL-3-[[2'-(1H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1,3-DIAZASPIRO [4, 4] NON-1-EN-4-ONE (IRBESARTAN)
    Publication number: 20120116093
    Abstract: A one pot process for the synthesis of Irbesartan comprising reacting 2-n-Butyl-1,3-Diazaspiro[4,4]Non-1-en-4-one (Formula III) and Bromomethyl Cyanobiphenyl (Formula IV) in the presence of base and water with the optional use of PTC to give formula II from which Irbesartan is obtained by reacting with sodium azide and triethylamine hydrochloride in the presence of a non polar solvent.
    Type: Application
    Filed: November 19, 2009
    Publication date: May 10, 2012
    Applicant: CTX Life Sciences Pvt. Ltd
    Inventors: Prakash Yashwant Kolhe, Rajesh Dilip Joshi, Bimal Kumar Srivastava, Nitin Jerambhai Patel, Sanket Sureshbhai Gajjar
  • Process for preparation of Gabapentin
    Patent number: 7196216
    Abstract: A process for producing gabapentin, (1-(aminomethyl)-1-cyclohexaneacetic acid) from gabapentin hydrochloride salt. In the disclosed process, the gabapentin hydrochloride is converted to gabapentin using an inorganic base, such as barium hydroxide. Gabapentin hydrochloride is converted to gabapentin sulfate which in turn is converted to free base using barium hydroxide. The process is directed to improvement in the manufacture of gabapentin which would be industrially feasible and effective. Gabapentin obtained following the process of the invention is suitable as a drug especially in the treatment of cerebral diseases such as epilepsy.
    Type: Grant
    Filed: November 18, 2002
    Date of Patent: March 27, 2007
    Assignee: Nicholas Piramal India Limited
    Inventors: Jagdish Chand Saigal, Rajender Pershad Gupta, Rajesh Vinodrai Naik, Araddy Rajshekhar, Rajesh Dilip Joshi