Patents by Inventor Rajesh Jayachandran

Rajesh Jayachandran has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Coronin 1 modulators for the treatment of autoimmune and lymphoproliferative disorders and mycobacterial infections
    Patent number: 8728438
    Abstract: The invention relates to the treatment of mycobacterial infections, autoimmune disorders, lymphoproliferative disorders and induction of immunosuppression following transplantation using coronin 1 and modulators of coronin 1. Particular modulators of coronin 1 are compounds which inhibit the production of coronin 1 or the formation of active coronin 1 from a coronin 1 precursor, partly or entirely inactivate coronin 1, inhibit concentration of coronin 1 at the site of T cell activation, or inhibit the coronin 1 mediated signaling pathway downstream of the T cell receptor. Examples of such modulators are antibody or antibody fragments, coronin 1 peptide fragments or corresponding phosphopeptides, or anti-sense oligonucleotides, e.g. siRNA or shRNA.
    Type: Grant
    Filed: July 29, 2013
    Date of Patent: May 20, 2014
    Assignee: University of Basel
    Inventors: Jean Pieters, Rajesh Jayachandran
  • CORONIN 1 MODULATORS FOR THE TREATMENT OF AUTOIMMUNE AND LYMPHOPROLIFERATIVE DISORDERS AND MYCOBACTERIAL INFECTIONS
    Publication number: 20130336966
    Abstract: The invention relates to the treatment of mycobacterial infections, autoimmune disorders, lymphoproliferative disorders and induction of immunosuppression following transplantation using coronin 1 and modulators of coronin 1. Particular modulators of coronin 1 are compounds which inhibit the production of coronin 1 or the formation of active coronin 1 from a coronin 1 precursor, partly or entirely inactivate coronin 1, inhibit concentration of coronin 1 at the site of T cell activation, or inhibit the coronin 1 mediated signaling pathway downstream of the T cell receptor. Examples of such modulators are antibody or antibody fragments, coronin 1 peptide fragments or corresponding phosphopeptides, or anti-sense oligonucleotides, e.g. siRNA or shRNA.
    Type: Application
    Filed: July 29, 2013
    Publication date: December 19, 2013
    Applicant: UNIVERSITY OF BASEL
    Inventors: Jean PIETERS, Rajesh JAYACHANDRAN
  • Coronin 1 modulators for the treatment of autoimmune and Lymphoproliferative disorders and mycobacterial infections
    Patent number: 8518372
    Abstract: The invention relates to the treatment of mycobacterial infections, autoimmune disorders, lymphoproliferative disorders and induction of immunosuppression following transplantation using coronin 1 and modulators of coronin 1. Particular modulators of coronin 1 are compounds which inhibit the production of coronin 1 or the formation of active coronin 1 from a coronin 1 precursor, partly or entirely inactivate coronin 1, inhibit concentration of coronin 1 at the site of T cell activation, or inhibit the coronin 1 mediated signaling pathway downstream of the T cell receptor. Examples of such modulators are antibody or antibody fragments, coronin 1 peptide fragments or corresponding phosphopeptides, or anti-sense oligonucleotides, e.g. siRNA or shRNA.
    Type: Grant
    Filed: March 23, 2007
    Date of Patent: August 27, 2013
    Assignee: University of Basel
    Inventors: Jean Pieters, Rajesh Jayachandran
  • Method and Apparatus for Controlling Device Operating Mode
    Publication number: 20130137413
    Abstract: In a non-limiting and example embodiment, a method is provided for remotely managing operating modes of a mobile communications device, comprising: detecting an operating mode change command received by a mobile communications device in a message from a wireless access device, and changing an operating mode of the mobile communications device in response to the operating mode change command, the operating mode change affecting user interface output of the mobile communications device.
    Type: Application
    Filed: February 7, 2012
    Publication date: May 30, 2013
    Applicant: NOKIA CORPORATION
    Inventor: Rajesh JAYACHANDRAN
  • Coronin 1 Modulators for the Treatment of Autoimmune and Lymphoproliferative Disorders and Mycobacterial Infections
    Publication number: 20100008931
    Abstract: The invention relates to the treatment of mycobacterial infections, autoimmune disorders, lymphoproliferative disorders and induction of immunosuppression following transplantation using coronin 1 and modulators of coronin 1. Particular modulators of coronin 1 are compounds which inhibit the production of coronin 1 or the formation of active coronin 1 from a coronin 1 precursor, partly or entirely inactivate coronin 1, inhibit concentration of coronin 1 at the site of T cell activation, or inhibit the coronin 1 mediated signaling pathway downstream of the T cell receptor Examples of such modulators are antibody or antibody fragments, coronin 1 peptide fragments or corresponding phosphopeptides, or anti-sense oligonucleotides, e.g. siRNA or shRNA.
    Type: Application
    Filed: March 23, 2007
    Publication date: January 14, 2010
    Inventors: Jean Pieters, Rajesh Jayachandran