Patents by Inventor Rajesh Karuturi

Rajesh Karuturi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Sulfated and unsulfated flavonoid oligomers as cancer therapeutics
    Patent number: 9850221
    Abstract: Sulfated and unsulfated flavonoid oligomers as inhibitors of cancer stem cells (CSCs) are provided. In particular, sulfated flavonoid dimers are shown to selectively inhibit CSCs growth and self-renewal both in vitro and in vivo.
    Type: Grant
    Filed: November 7, 2014
    Date of Patent: December 26, 2017
    Assignee: VIRGINIA COMMONWEALTH UNIVERSITY
    Inventors: Umesh R. Desai, Rajesh Karuturi, Bhaumik B. Patel, Nirmita J. Patel
  • Allosteric modulators of factor XIa as anticoagulant agents
    Patent number: 9758459
    Abstract: Compounds which allosterically modulate and/or inhibit factor XIa activity are provided, as are methods of their use. These compounds include i) sulfated gallolyl glucosides, ii) sulfated quinazolinones, and iii) sulfated inositol analogs. The compounds used as anticoagulant agents.
    Type: Grant
    Filed: November 12, 2013
    Date of Patent: September 12, 2017
    Assignee: Virginia Commonwealth University
    Inventors: Umesh R. Desai, Rajesh Karuturi, Akul Mehta, Rami A. Al-Horani
  • ALLOSTERIC MODULATORS OF FACTOR XIa AS ANTICOAGULANT AGENTS
    Publication number: 20160311842
    Abstract: Compounds which allosterically modulate and/or inhibit factor XIa activity are provided, as are methods of their use. These compounds include i) sulfated gallolyl glucosides, ii) sulfated quinazolinones, and iii) sulfated inositol analogs. The compounds used as anticoagulant agents.
    Type: Application
    Filed: November 12, 2013
    Publication date: October 27, 2016
    Inventors: Umesh R. DESAI, Rajesh KARUTURI, Akul MEHTA, Rami A. AL-HORANI
  • SULFATED AND UNSULFATED FLAVONOID OLIGOMERS AS CANCER THERAPEUTICS
    Publication number: 20160280676
    Abstract: Sulfated and unsulfated flavonoid oligomers as inhibitors of cancer stem cells (CSCs) are provided. In particular, sulfated flavonoid dimers are shown to selectively inhibit CSCs growth and self-renewal both in vitro and in vivo.
    Type: Application
    Filed: November 7, 2014
    Publication date: September 29, 2016
    Inventors: Umesh R. Desai, Rajesh Karuturi, Bhaumik B. Patel, Nirmita J. Patel