Patents by Inventor Rajesh Shrotriya

Rajesh Shrotriya has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Paclitaxel formulation
    Patent number: 6538020
    Abstract: A pharmaceutical formulation is provided for delivering paclitaxel in vivo comprising: paclitaxel, a water-miscible amide and a pharmaceutically-acceptable, water-miscible solubilizer selected from the group consisting of solubilizers having the general structures R1COOR2, R1CONR2, and R1COR2, wherein R1 is a hydrophobic C3-C50 alkane, alkene or alkyne and R2 is a hydrophilic moiety.
    Type: Grant
    Filed: September 5, 2001
    Date of Patent: March 25, 2003
    Assignee: Super Gen, Inc.
    Inventors: Rajashree Joshi-Hangal, Ashok Y. Gore, Joseph Rubinfeld, Rajesh Shrotriya
  • Paclitaxel formulation
    Patent number: 6509370
    Abstract: A pharmaceutical formulation is provided for delivering paclitaxel in vivo comprising: water and micelles comprising paclitaxel and a pharmaceutically-acceptable, water-miscible solubilizer forming the micelles, the solubilizer selected from the group consisting of solubilizers having the general structures R1COOR2, R1CONR2, and R1COR2, wherein R1 is a hydrophobic C3-C50 alkane, alkene or alkyne and R2 is a hydrophilic moiety. The solubilizer is selected such that it does not have a pKa less than about 6.
    Type: Grant
    Filed: July 9, 2002
    Date of Patent: January 21, 2003
    Assignee: SuperGen, Inc.
    Inventors: Rajashree Joshi-Hangal, Ashok Y. Gore, Joseph Rubinfeld, Rajesh Shrotriya
  • Paclitaxel formulation
    Publication number: 20020103254
    Abstract: A pharmaceutical formulation is provided for delivering paclitaxel in vivo comprising: paclitaxel, a water-miscible amide and a pharmaceutically-acceptable, water-miscible solubilizer selected from the group consisting of solubilizers having the general structures
    Type: Application
    Filed: September 5, 2001
    Publication date: August 1, 2002
    Inventors: Rajashree Joshi-Hangal, Ashok Y. Gore, Joseph Rubinfeld, Rajesh Shrotriya
  • Oral formulation for paclitaxel
    Patent number: 6319943
    Abstract: A pharmaceutical formulation is provided for delivering paclitaxel in vivo comprising: water and micelles comprising paclitaxel and a pharrnaceutically-acceptable, water-miscible solubilizer forming the micelles, the solubilizer selected from the group consisting of solubilizers having the general structures R1COOR2, R1CONR2, and R1COR2, wherein R1 is a hydrophobic C3-C50 alkane, alkene or alkyne and R2 is a hydrophilic moiety. The solubilizer is selected such that it does not have a pKa less than about 6.
    Type: Grant
    Filed: September 20, 2000
    Date of Patent: November 20, 2001
    Assignee: SuperGen, Inc
    Inventors: Rajashree Joshi, Ashok Y. Gore, Joseph Rubinfeld, Rajesh Shrotriya
  • Formulation for paclitaxel
    Patent number: 6136846
    Abstract: A pharmaceutical formulation is provided for delivering paclitaxel in vivo comprising: water and micelles comprising paclitaxel and a pharmaceutically-acceptable, water-miscible solubilizer forming the micelles, the solubilizer selected from the group consisting of solubilizers having the general structuresR.sub.1 COOR.sub.2, R.sub.1 CONR.sub.2, and R.sub.1 COR.sub.2,wherein R.sub.1 is a hydrophobic C.sub.3 -C.sub.50 alkane, alkene or alkyne and R.sub.2 is a hydrophilic moiety. The solubilizer is selected such that it does not have a pKa less than about 6.
    Type: Grant
    Filed: October 25, 1999
    Date of Patent: October 24, 2000
    Assignee: Supergen, Inc.
    Inventors: Joseph Rubinfeld, Ashok Y. Gore, Rajashree Joshi, Rajesh Shrotriya
  • Water-miscible pharmaceutical compositions
    Patent number: 6017948
    Abstract: Disclosed are compositions comprising paclitaxel; and a pharmaceutically-acceptable, water-miscible, non-aqueous solvent, together with kits comprising the composition and methods of using the composition.
    Type: Grant
    Filed: October 30, 1998
    Date of Patent: January 25, 2000
    Assignee: Supergen, Inc.
    Inventors: Joseph Rubinfeld, Ashok Y. Gore, Rajashree Joshi, Rajesh Shrotriya