Patents by Inventor Rajeshwari Mehta

Rajeshwari Mehta has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions comprising cupredoxins for treating cancer
    Patent number: 10675326
    Abstract: The present invention discloses methods and materials for killing and/or inhibiting the growth of a cancer cell via preferential entry of a cytotoxic compound. Preferential entry of the cytotoxic compound is accomplished by the use of protein transduction domains derived from cupredoxins, including the p18 and p28 truncations of azurin.
    Type: Grant
    Filed: December 11, 2017
    Date of Patent: June 9, 2020
    Inventors: Brad N. Taylor, Rajeshwari Mehta, Tohru Yamada, Craig Beattie, Tapas Das Gupta
  • COMPOSITIONS AND METHODS TO PREVENT CANCER WITH CUPREDOXINS
    Publication number: 20190046605
    Abstract: The present invention discloses methods and materials for killing and/or inhibiting the growth of a cancer cell via preferential entry of a cytotoxic compound. Preferential entry of the cytotoxic compound is accomplished by the use of protein transduction domains derived from cupredoxins, including the p18 and p28 truncations of azurin.
    Type: Application
    Filed: December 11, 2017
    Publication date: February 14, 2019
    Inventors: Brad N. Taylor, Rajeshwari Mehta, Tohru Yamada, Craig Beattie, Tapas Das Gupta
  • Methods to treat cancer with cupredoxins
    Patent number: 9968685
    Abstract: The present invention discloses methods and materials for killing and/or inhibiting the growth of a cancer cell via preferential entry of a cytotoxic compound. Preferential entry of the cytotoxic compound is accomplished by the use of protein transduction domains derived from cupredoxins, including the p18 and p28 truncations of azurin.
    Type: Grant
    Filed: December 18, 2008
    Date of Patent: May 15, 2018
    Inventors: Brad N. Taylor, Rajeshwari Mehta, Tohru Yamada, Craig Beattie, Tapas Das Gupta
  • Compositions and methods to prevent cancer with cupredoxins
    Patent number: 8158574
    Abstract: The present invention relates to compositions and methods comprising chemopreventive agents that may be cupredoxin(s) or variants, derivatives and structural equivalents of cupredoxins, and at least one other chemopreventive agent. Specifically, these compositions may comprise azurin from Pseudomonas aeruginosa, and/or the 50-77 residue region of azurin (p28). The at least one other chemopreventive agent may comprise an antiestrogen such as Tamoxifen. The compositions of the invention may be used to prevent the development of premalignant lesions in mammalian cells, tissues and animals, and thus prevent cancer.
    Type: Grant
    Filed: December 17, 2008
    Date of Patent: April 17, 2012
    Assignee: CDG Therapeutics, Inc.
    Inventors: Tapas Das Gupta, Rajendra G. Mehta, Rajeshwari Mehta, Craig Beattie
  • COMPOSITIONS AND METHODS TO PREVENT CANCER WITH CUPREDOXINS
    Publication number: 20090215692
    Abstract: The present invention relates to compositions and methods comprising chemopreventive agents that may be cupredoxin(s) or variants, derivatives and structural equivalents of cupredoxins, and at least one other chemopreventive agent. Specifically, these compositions may comprise azurin from Pseudomonas aeruginosa, and/or the 50-77 residue region of azurin (p28). The at least one other chemopreventive agent may comprise an antiestrogen such as Tamoxifen. The compositions of the invention may be used to prevent the development of premalignant lesions in mammalian cells, tissues and animals, and thus prevent cancer.
    Type: Application
    Filed: December 17, 2008
    Publication date: August 27, 2009
    Inventors: Tapas Das Gupta, Rajendra G. Mehta, Rajeshwari Mehta, Craig Beattie
  • COMPOSITIONS AND METHODS TO PREVENT CANCER WITH CUPREDOXINS
    Publication number: 20090202441
    Abstract: The present invention discloses methods and materials for killing and/or inhibiting the growth of a cancer cell via preferential entry of a cytotoxic compound. Preferential entry of the cytotoxic compound is accomplished by the use of protein transduction domains derived from cupredoxins, including the p18 and p28 truncations of azurin.
    Type: Application
    Filed: December 18, 2008
    Publication date: August 13, 2009
    Inventors: Brad N. Taylor, Rajeshwari Mehta, Tohru Yamada, Craig Beattie, Tapas Das Gupta