Patents by Inventor Rajeswari KASI

Rajeswari KASI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR TREATING CHEMORESISTANT CANCER-INITIATING CELLS
    Publication number: 20220105114
    Abstract: The disclosure provides methods of treating cancer by selectively inhibiting p-S552-?-catenin, p-T217-?-catenin, T332-?-catenin, and/or p-S675-?-catenin production and/or activity. Such methods also and/or limit cancer-initiating cells.
    Type: Application
    Filed: October 12, 2021
    Publication date: April 7, 2022
    Inventors: Rajeswari KASI, Linheng Ll, Xiuling LU, John M. PERRY, Gurusingham Sitta SITTAMPALAM, Anuradha ROY, Xi C. HE
  • Methods for treating chemoresistant cancer-initiating cells
    Patent number: 11173173
    Abstract: The disclosure provides methods of treating cancer by selectively inhibiting p-S552-?-catenin, p-T217-?-catenin, p-T332-?-catenin, and/or p-S675-?-catenin production and/or activity. Such methods also and/or limit cancer-initiating cells.
    Type: Grant
    Filed: July 28, 2016
    Date of Patent: November 16, 2021
    Assignees: UNIVERSITY OF CONNECTICUT, UNIVERSITY OF KANSAS, STOWERS INSTITUTE FOR MEDICAL RESEARCH
    Inventors: Rajeswari Kasi, Linheng Li, Xiuling Lu, John M. Perry, Gurusingham Sitta Sittampalam, Anuradha Roy, Xi C. He
  • Self-assembled brush block copolymer-nanoparticles for drug delivery
    Patent number: 11103523
    Abstract: The invention provides amphiphilic liquid crystalline brush block copolymers that can readily self-assemble to nanoparticles in aqueous solutions and also allow for encapsulation of hydrophobic pharmaceutically active molecules.
    Type: Grant
    Filed: October 7, 2014
    Date of Patent: August 31, 2021
    Assignee: University of Connecticut
    Inventors: Xiuling Lu, Rajeswari Kasi, Thanh-Huyen Tran, Chi Thanh Nguyen, Prashant Deshmukh
  • METHODS FOR TREATING CHEMORESISTANT CANCER-INITIATING CELLS
    Publication number: 20180207184
    Abstract: The disclosure provides methods of treating cancer by selectively inhibiting p-S552-?-catenin, p-T217-?-catenin, p-T332-?-catenin, and/or p-S675-?-catenin production and/or activity. Such methods also and/or limit cancer-initiating cells.
    Type: Application
    Filed: July 28, 2016
    Publication date: July 26, 2018
    Inventors: Rajeswari KASI, Linheng Ll, Xiuling LU, John M. PERRY, Gurusingham Sitta SITTAMPALAM, Anuradha ROY, Xi C. HE
  • Bio-reducible self-assembled liquid crystalline block copolymer for drug delivery
    Patent number: 9975983
    Abstract: The disclosure provides biodegradable amphiphilic liquid crystalline copolymers that can readily self-assemble to nanoparticles in aqueous solutions and also allow for encapsulation of hydrophobic pharmaceutically active molecules.
    Type: Grant
    Filed: October 15, 2015
    Date of Patent: May 22, 2018
    Assignee: University of Connecticut
    Inventors: Xiuling Lu, Rajeswari Kasi, Thanh-Huyen Tran, Chi Thanh Nguyen
  • BIO-REDUCIBLE SELF-ASSEMBLED LIQUID CRYSTALLINE BLOCK COPOLYMER FOR DRUG DELIVERY
    Publication number: 20170240680
    Abstract: The disclosure provides biodegradable amphiphilic liquid crystalline copolymers that can readily self-assemble to nanoparticles in aqueous solutions and also allow for encapsulation of hydrophobic pharmaceutically active molecules.
    Type: Application
    Filed: October 15, 2015
    Publication date: August 24, 2017
    Inventors: Xiuling LU, Rajeswari KASI, Thanh-Huyen TRAN, Chi Thanh NGUYEN
  • Self-Assembled Brush Block Copolymer-Nanoparticles for Drug Delivery
    Publication number: 20160243141
    Abstract: The invention provides amphiphilic liquid crystalline brush block copolymers that can readily self-assemble to nanoparticles in aqueous solutions and also allow for encapsulation of hydrophobic pharmaceutically active molecules.
    Type: Application
    Filed: October 7, 2014
    Publication date: August 25, 2016
    Inventors: Xiuling LU, Rajeswari KASI, Thanh-Huyen TRAN, Chi Thanh NGUYEN, Prashant DESHMUKH