Abstract: Methods and apparatus are provided for determining the refractive index of a downhole fluid. Two unalike crystals are provided having faces in contact with fluid in the fluid flow line of a borehole tool. The crystals are chosen to have different refractive indices and/or different angles of incidence, but to provide total internal reflection for light that is directed through the crystals to the crystal/fluid interface. The measured attenuations for each crystal are used in conjunction with the known refractive indices and angles of incidence of said crystals to determine the refractive index of the fluid.

Abstract: Consolidated porous media samples and methods for their manufacture are described herein. An assembly has an outer tube having a first softening temperature and a sintered glass construct formed from plurality of beads of multiple sizes. The sintered glass construct defines pores and at least one fracture or channel. The assembly is formed by suspending at least one sheet or wire of dissolvable material in the outer tube, packing beads of different sizes around the sheet or wire, sintering the beads with the sheet or wire located therein at a temperature below the softening temperature of the tube, and dissolving the sheet or wire to generate a sintered construct defining at least one fracture or channel.

Abstract: Methods and apparatus are provided for determining the refractive index of a downhole fluid. Two unalike crystals are provided having faces in contact with fluid in the fluid flow line of a borehole tool. The crystals are chosen to have different refractive indices and/or different angles of incidence, but to provide total internal reflection for light that is directed through the crystals to the crystal/fluid interface. The measured attenuations for each crystal are used in conjunction with the known refractive indices and angles of incidence of said crystals to determine the refractive index of the fluid.

Abstract: Consolidated porous media samples and methods for their manufacture are described herein. An assembly has an outer tube having a first softening temperature and a sintered glass construct formed from plurality of beads of multiple sizes. The sintered glass construct defines pores and at least one fracture or channel. The assembly is formed by suspending at least one sheet or wire of dissolvable material in the outer tube, packing beads of different sizes around the sheet or wire, sintering the beads with the sheet or wire located therein at a temperature below the softening temperature of the tube, and dissolving the sheet or wire to generate a sintered construct defining at least one fracture or channel.

Abstract: An immunotherapy protocol in which leukocytes are cultured in the presence of interleukin-2 in a hollow fiber cartridge perfusion system for at least four days to achieve a harvest yield of at least 100% of leukocytes with respect to the number of cells initially present in the hollow cartridge, and where the leukocytes have a lytic activity at least equal to that of cells grown in a static culturing system and where the lytic activity of the cells following the culture period in the hollow fiber is at least equal to cells grown in a static culturing system.

Abstract: A method for culturing leukocytes includes the culturing of leukocytes in a hollow fiber cartridge perfusion system for at least four days to achieve a harvest yield of at least 100% of leukocytes, the leukocytes having a lytic activity at least equal to that of cells grown in a static culturing system.