Patents by Inventor Rajiv Chopra
Rajiv Chopra has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240122534Abstract: Methods, apparatuses, systems, and implementations for inductive heating of a foreign metallic implant are disclosed. A foreign metallic implant may be heated via AMF pulses to ensure that the surface of the foreign metallic implant heats in a uniform manner. As the surface temperature of the foreign metallic implant rises, acoustic signatures may be detected by acoustic sensors that may indicate that tissue may be heating to an undesirable level approaching a boiling point. Once these acoustic signatures are detected, the AMF pulses may be shut off for a time period to allow the surface temperature of the implant to cool before applying additional AMF pulses. In this manner, the surface temperature of a foreign metallic implant may be uniformly heated to a temperature adequate to treat bacterial biofilm buildup on the surface of the foreign metallic implant without damaging surrounding tissue.Type: ApplicationFiled: December 22, 2023Publication date: April 18, 2024Inventors: Rajiv CHOPRA, David GREENBERG, Yonatan CHATZINOFF
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Patent number: 11955016Abstract: An interface system for flight deck communications includes a chatbot configured to perform a conversation with a pilot. The conversation includes speech communications, visual communications using a display, or both. The interface system also includes a dynamic conversational graph generator. The dynamic conversational graph generator is configured to perform a set of functions including determining a flight operational procedure from the conversation with the pilot. The set of functions also include providing information associated with the flight operational procedure to the chatbot for communicating to the pilot. The set of functions also include responding to any requests received from the pilot by the chatbot during the conversation with the pilot.Type: GrantFiled: January 12, 2022Date of Patent: April 9, 2024Assignee: THE BOEING COMPANYInventors: Seema Chopra, Kiran Gopala Krishna, Rajiv Veeranna
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Publication number: 20240033533Abstract: An embodiment includes: (1) determining a first orientation of first and second portions of a first image with respect to one another, wherein the first portion depicts a first metallic implant and the second portion depicts a first coil, wherein the first orientation is based on: (a) a first distance between the first and second portions with respect to one another, and (b) a first direction between the first and second portions with respect to one another; (2) select a first target orientation for the first metallic implant and the first coil with respect to one another from a library of target orientations between implants and coils; (3) determine a first difference between the first orientation and the first target orientation; and (4) output first reorientation instructions via the at least one I/O port in response to determining the first difference between the first orientation and the first target orientation.Type: ApplicationFiled: December 20, 2021Publication date: February 1, 2024Inventors: David Greenberg, John Tepper, Rajiv Chopra
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Patent number: 11864911Abstract: Methods, apparatuses, systems, and implementations for inductive heating of a foreign metallic implant are disclosed. A foreign metallic implant may be heated via AMF pulses to ensure that the surface of the foreign metallic implant heats in a uniform manner. As the surface temperature of the foreign metallic implant rises, acoustic signatures may be detected by acoustic sensors that may indicate that tissue may be heating to an undesirable level approaching a boiling point. Once these acoustic signatures are detected, the AMF pulses may be shut off for a time period to allow the surface temperature of the implant to cool before applying additional AMF pulses. In this manner, the surface temperature of a foreign metallic implant may be uniformly heated to a temperature adequate to treat bacterial biofilm buildup on the surface of the foreign metallic implant without damaging surrounding tissue.Type: GrantFiled: November 22, 2022Date of Patent: January 9, 2024Assignee: The Board Of Regents Of The University Of Texas SystemInventors: Rajiv Chopra, David Greenberg, Yonatan Chatzinoff
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Publication number: 20230079108Abstract: Methods, apparatuses, systems, and implementations for inductive heating of a foreign metallic implant are disclosed. A foreign metallic implant may be heated via AMF pulses to ensure that the surface of the foreign metallic implant heats in a uniform manner. As the surface temperature of the foreign metallic implant rises, acoustic signatures may be detected by acoustic sensors that may indicate that tissue may be heating to an undesirable level approaching a boiling point. Once these acoustic signatures are detected, the AMF pulses may be shut off for a time period to allow the surface temperature of the implant to cool before applying additional AMF pulses. In this manner, the surface temperature of a foreign metallic implant may be uniformly heated to a temperature adequate to treat bacterial biofilm buildup on the surface of the foreign metallic implant without damaging surrounding tissue.Type: ApplicationFiled: November 22, 2022Publication date: March 16, 2023Inventors: Rajiv CHOPRA, David GREENBERG, Yonatan CHATZINOFF
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Patent number: 11510615Abstract: Methods, apparatuses, systems, and implementations for inductive heating of a foreign metallic implant are disclosed. A foreign metallic implant may be heated via AMF pulses to ensure that the surface of the foreign metallic implant heats in a uniform manner. As the surface temperature of the foreign metallic implant rises, acoustic signatures may be detected by acoustic sensors that may indicate that tissue may be heating to an undesirable level approaching a boiling point. Once these acoustic signatures are detected, the AMF pulses may be shut off for a time period to allow the surface temperature of the implant to cool before applying additional AMF pulses. In this manner, the surface temperature of a foreign metallic implant may be uniformly heated to a temperature adequate to treat bacterial biofilm buildup on the surface of the foreign metallic implant without damaging surrounding tissue.Type: GrantFiled: January 14, 2019Date of Patent: November 29, 2022Assignee: The Board of Regents of the University of Texas SystemInventors: Rajiv Chopra, David Greenberg, Yonatan Chatzinoff
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Patent number: 11312766Abstract: Provided herein are monoclonal antibodies (e.g., human antibodies) binding to human Growth Differentiation Factor 15 protein (hereinafter, sometimes referred to as “GDF15”), and pharmaceutical compositions and methods of treatment comprising the same.Type: GrantFiled: April 26, 2017Date of Patent: April 26, 2022Assignee: NOVARTIS AGInventors: Hong Chen, Rajiv Chopra, Seung Wan Hahm, Norio Hamamatsu, Ryan Scott Streeper, Mei Xu
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Publication number: 20200181216Abstract: The disclosure relates to fusion polypeptides comprising serum albumin or a functional variant thereof and GDF15 protein or a functional variant thereof, and to pharmaceutical compositions that contain the fusion polypeptides, nucleic acids that encode the fusion polypeptides, methods of making the polypeptides and use of the polypeptides to decreasing appetite, decreasing body weight and treating metabolic diseases.Type: ApplicationFiled: August 15, 2019Publication date: June 11, 2020Inventors: Rajiv CHOPRA, Norio HAMAMATSU, Ryan STREEPER, Brian Edward VASH
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Publication number: 20200111107Abstract: An unauthorized-product detection system may compare data representing various authentication markers of items presumed to have been produced or sourced by a particular entity with stored data representing valid authentication markers of items produced or sourced by the particular entity. The authentication markers may represent inherent physical characteristics of the items or their packaging, or may be generated and applied to the items or their packaging to facilitate counterfeit detection and/or for other purposes. The data (some of which may be encrypted) may be captured using high-resolution cameras, scanners, or other devices, and then communicated to the unauthorized-product detection system for analysis. The system may maintain a data store of data representing captured or valid authentication markers and may store tracking information reflecting the use of various authentication markers.Type: ApplicationFiled: November 15, 2019Publication date: April 9, 2020Applicant: Amazon Technologies, Inc.Inventors: Douglas James Herrington, Shehzad Mevawalla, Rajiv Chopra, Joseph Sirosh, Sachin Chouksey, Maria Christine Renz, Sarah Ann Wood, Jeffrey P. Bezos
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Patent number: 10482471Abstract: An unauthorized-product detection system may compare data representing various authentication markers of items presumed to have been produced or sourced by a particular entity with stored data representing valid authentication markers of items produced or sourced by the particular entity. The authentication markers may represent inherent physical characteristics of the items or their packaging, or may be generated and applied to the items or their packaging to facilitate counterfeit detection and/or for other purposes. The data (some of which may be encrypted) may be captured using high-resolution cameras, scanners, or other devices, and then communicated to the unauthorized-product detection system for analysis. The system may maintain a data store of data representing captured or valid authentication markers and may store tracking information reflecting the use of various authentication markers.Type: GrantFiled: January 16, 2013Date of Patent: November 19, 2019Assignee: Amazon Technologies, Inc.Inventors: Douglas James Herrington, Shehzad Mevawalla, Rajiv Chopra, Joseph Sirosh, Sachin Chouksey, Maria Christine Renz, Sarah Ann Wood, Jeffrey P. Bezos
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Patent number: 10395243Abstract: Financial transactions, such as buying and selling, may be facilitated by merchant-based shadow account numbers. A master account may contain several associated shadow accounts. Each shadow account may in turn be associated with a specific merchant or group of merchants. Merchants and users may store and use the shadow account numbers rather than the master account numbers. Stolen or otherwise compromised shadow account numbers are useless with other non-associated merchants. Furthermore, the shadow numbers may be easily invalidated while leaving the master account untouched.Type: GrantFiled: March 13, 2013Date of Patent: August 27, 2019Assignee: Amazon Technologies, Inc.Inventors: Jesper M. Johansson, David H. Hijirida, Peter S. Vosshall, Rajiv Chopra, Terrance Douglas Hanold
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Publication number: 20190159725Abstract: Methods, apparatuses, systems, and implementations for inductive heating of a foreign metallic implant are disclosed. A foreign metallic implant may be heated via AMF pulses to ensure that the surface of the foreign metallic implant heats in a uniform manner. As the surface temperature of the foreign metallic implant rises, acoustic signatures may be detected by acoustic sensors that may indicate that tissue may be heating to an undesirable level approaching a boiling point. Once these acoustic signatures are detected, the AMF pulses may be shut off for a time period to allow the surface temperature of the implant to cool before applying additional AMF pulses. In this manner, the surface temperature of a foreign metallic implant may be uniformly heated to a temperature adequate to treat bacterial biofilm buildup on the surface of the foreign metallic implant without damaging surrounding tissue.Type: ApplicationFiled: January 14, 2019Publication date: May 30, 2019Inventors: Rajiv CHOPRA, David Greenberg, Yonatan Chatzinoff
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Patent number: 10300307Abstract: A focused ultrasound (“FUS”} system capable of use in a small bore imaging system, such as a small bore magnetic resonance imaging (“MRI”} system is provided. The FUS system generally includes an ultrasound transducer whose position is adjusted by a positioning system. The positioning system is sized to fit within the bore of the small bore imaging system. For instance, the positioning system can fit within a diameter of 150 millimeters or less.Type: GrantFiled: April 14, 2014Date of Patent: May 28, 2019Assignee: Sunnybrook Research InstituteInventors: Kullervo Hynynen, Anthony Chau, Rajiv Chopra
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Publication number: 20190135908Abstract: Provided herein are monoclonal antibodies (e.g., human antibodies) binding to human Growth Differentiation Factor 15 protein (hereinafter, sometimes referred to as “GDF15”), and pharmaceutical compositions and methods of treatment comprising the same.Type: ApplicationFiled: April 26, 2017Publication date: May 9, 2019Inventors: Hong CHEN, Rajiv CHOPRA, Seung Wan HAHM, Norio HAMAMATSU, Ryan Scott STREEPER, Mei XU
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Patent number: 10271889Abstract: An apparatus for cooling certain tissues in the vicinity of diseased or other tissue undergoing thermal treatment is disclosed. The present apparatus is configured and designed to have certain physical characteristics, e.g., certain acoustic and imaging responses. In some embodiments the present apparatus is compatible with magnetic resonance imaging (MRI) environments used in conjunction with the thermal treatment, or other imaging environments. In some embodiments the present apparatus is detectable by said MRI and is within the imaging field of view (FOV) but causes few or no imaging artifacts. Additionally, the present apparatus does not substantially interfere with the thermal treatment, e.g., ultrasonic therapy, which can proceed to heat the targeted volume of tissue while protective cooling of tissues near the diseased tissue by the present apparatus takes place.Type: GrantFiled: June 27, 2010Date of Patent: April 30, 2019Assignee: Sunnybrook Health Sciences CentreInventors: Michael J. Bronskill, Rajiv Chopra
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Patent number: 9931523Abstract: An apparatus for driving and controlling ultrasonic elements includes a computer-based host unit that determines driving characteristics with which to drive the ultrasonic elements; a microprocessor-based controller that receives an output from the host and provides signals representing a frequency and/or an amplitude characteristic; a frequency control circuit receiving the frequency characteristic signal; an amplitude control circuit receiving the amplitude characteristic signal; an RF amplifier acting on an output from the frequency and/or the amplitude control circuits to provide an amplified output signal corresponding to the frequency and/or amplitude characteristic; a coupling circuit that couples the amplified output signal to the ultrasonic elements and provides a forward output signal to a first RF detector circuit and a reverse output signal to a second RF detector circuit; and an analog-to-digital converter that receives an output of the RF detector circuits and provides a corresponding convertedType: GrantFiled: March 9, 2011Date of Patent: April 3, 2018Assignee: Profound Medical, Inc.Inventors: Cameron Mahon, Nicolas Yak, Rajiv Chopra, Mathew Asselin, Michael Bronskill
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Publication number: 20170204149Abstract: The disclosure relates to fusion polypeptides comprising serum albumin or a functional variant thereof and GDF15 protein or a functional variant thereof and to pharmaceutical compositions that contain the fusion polypeptides, nucleic acids that encode the fusion polypeptides, methods of making the polypeptides and use of the polypeptides to decreasing appetite, decreasing body weight and treating metabolic diseases.Type: ApplicationFiled: June 19, 2015Publication date: July 20, 2017Applicant: NOVARTIS AGInventors: Rajiv CHOPRA, Norio HAMAMATSU, Ryan Scott STREEPER, Brian Edward VASH
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Patent number: 9707413Abstract: An apparatus is disclosed for thermal therapy in a male prostate patient. The apparatus includes, in preferred embodiments, a long tubular element that is to be inserted into a patient's urethra so that a first tip end of it reaches up into the patient's diseased prostate. The elongated portion includes a narrow cylindrical tube within which an ultrasonic array is disposed along the long axis of the cylinder. Fluid is pumped into and out of a treatment zone of said patient as needed to control a temperature of a region in said treatment zone. A motorized driver is used to controllably rotate said elongated portion and the ultrasound array therein about the long axis of the apparatus so as to deliver acoustic energy to said diseased tissue. Various control and monitoring components may be used in conjunction with the present apparatus to design, control, and terminate the therapy.Type: GrantFiled: March 9, 2011Date of Patent: July 18, 2017Assignee: Profound Medical Inc.Inventors: Rajiv Chopra, Sean Donaldson, Cameron Mahon
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Publication number: 20160067527Abstract: A focused ultrasound (“FUS”} system capable of use in a small bore imaging system, such as a small bore magnetic resonance imaging (“MRI”} system is provided. The FUS system generally includes an ultrasound transducer whose position is adjusted by a positioning system. The positioning system is sized to fit within the bore of the small bore imaging system. For instance, the positioning system can fit within a diameter of 150 millimeters or less.Type: ApplicationFiled: April 14, 2014Publication date: March 10, 2016Inventors: Kullervo HYNYNEN, Anthony CHAU, Rajiv CHOPRA
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Patent number: 9101752Abstract: A focused ultrasound system includes an ultrasound transducer configured to emit focused ultrasound energy toward a subject and a positioning system configured to position the ultrasound transducer to localize the focused ultrasound energy within a target location. The positioning system includes a drive apparatus to translate the ultrasound transducer along at least one axis of motion and a motor controller to control the drive apparatus. The focused ultrasound system also includes a control system connected to the motor controller that is programmed to receive imaging/location data from an imaging system, determine positional coordinates of the target location based on the imaging/location data, and register the positional coordinates of the target location with the positioning system. The positional coordinates are sent to the motor controller via an input signal to cause the motor controller to control the drive apparatus so as to translate the ultrasound transducer.Type: GrantFiled: November 16, 2009Date of Patent: August 11, 2015Assignee: SUNNYBROOK HEALTH SCIENCES CENTREInventors: Rajiv Chopra, Kullervo Hynynen, Anthony Chau, Adam Christian Waspe