Patents by Inventor Rajiv Chopra

Rajiv Chopra has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10395243
    Abstract: Financial transactions, such as buying and selling, may be facilitated by merchant-based shadow account numbers. A master account may contain several associated shadow accounts. Each shadow account may in turn be associated with a specific merchant or group of merchants. Merchants and users may store and use the shadow account numbers rather than the master account numbers. Stolen or otherwise compromised shadow account numbers are useless with other non-associated merchants. Furthermore, the shadow numbers may be easily invalidated while leaving the master account untouched.
    Type: Grant
    Filed: March 13, 2013
    Date of Patent: August 27, 2019
    Assignee: Amazon Technologies, Inc.
    Inventors: Jesper M. Johansson, David H. Hijirida, Peter S. Vosshall, Rajiv Chopra, Terrance Douglas Hanold
  • Publication number: 20190159725
    Abstract: Methods, apparatuses, systems, and implementations for inductive heating of a foreign metallic implant are disclosed. A foreign metallic implant may be heated via AMF pulses to ensure that the surface of the foreign metallic implant heats in a uniform manner. As the surface temperature of the foreign metallic implant rises, acoustic signatures may be detected by acoustic sensors that may indicate that tissue may be heating to an undesirable level approaching a boiling point. Once these acoustic signatures are detected, the AMF pulses may be shut off for a time period to allow the surface temperature of the implant to cool before applying additional AMF pulses. In this manner, the surface temperature of a foreign metallic implant may be uniformly heated to a temperature adequate to treat bacterial biofilm buildup on the surface of the foreign metallic implant without damaging surrounding tissue.
    Type: Application
    Filed: January 14, 2019
    Publication date: May 30, 2019
    Inventors: Rajiv CHOPRA, David Greenberg, Yonatan Chatzinoff
  • Patent number: 10300307
    Abstract: A focused ultrasound (“FUS”} system capable of use in a small bore imaging system, such as a small bore magnetic resonance imaging (“MRI”} system is provided. The FUS system generally includes an ultrasound transducer whose position is adjusted by a positioning system. The positioning system is sized to fit within the bore of the small bore imaging system. For instance, the positioning system can fit within a diameter of 150 millimeters or less.
    Type: Grant
    Filed: April 14, 2014
    Date of Patent: May 28, 2019
    Assignee: Sunnybrook Research Institute
    Inventors: Kullervo Hynynen, Anthony Chau, Rajiv Chopra
  • Publication number: 20190135908
    Abstract: Provided herein are monoclonal antibodies (e.g., human antibodies) binding to human Growth Differentiation Factor 15 protein (hereinafter, sometimes referred to as “GDF15”), and pharmaceutical compositions and methods of treatment comprising the same.
    Type: Application
    Filed: April 26, 2017
    Publication date: May 9, 2019
    Inventors: Hong CHEN, Rajiv CHOPRA, Seung Wan HAHM, Norio HAMAMATSU, Ryan Scott STREEPER, Mei XU
  • Patent number: 10271889
    Abstract: An apparatus for cooling certain tissues in the vicinity of diseased or other tissue undergoing thermal treatment is disclosed. The present apparatus is configured and designed to have certain physical characteristics, e.g., certain acoustic and imaging responses. In some embodiments the present apparatus is compatible with magnetic resonance imaging (MRI) environments used in conjunction with the thermal treatment, or other imaging environments. In some embodiments the present apparatus is detectable by said MRI and is within the imaging field of view (FOV) but causes few or no imaging artifacts. Additionally, the present apparatus does not substantially interfere with the thermal treatment, e.g., ultrasonic therapy, which can proceed to heat the targeted volume of tissue while protective cooling of tissues near the diseased tissue by the present apparatus takes place.
    Type: Grant
    Filed: June 27, 2010
    Date of Patent: April 30, 2019
    Assignee: Sunnybrook Health Sciences Centre
    Inventors: Michael J. Bronskill, Rajiv Chopra
  • Patent number: 9931523
    Abstract: An apparatus for driving and controlling ultrasonic elements includes a computer-based host unit that determines driving characteristics with which to drive the ultrasonic elements; a microprocessor-based controller that receives an output from the host and provides signals representing a frequency and/or an amplitude characteristic; a frequency control circuit receiving the frequency characteristic signal; an amplitude control circuit receiving the amplitude characteristic signal; an RF amplifier acting on an output from the frequency and/or the amplitude control circuits to provide an amplified output signal corresponding to the frequency and/or amplitude characteristic; a coupling circuit that couples the amplified output signal to the ultrasonic elements and provides a forward output signal to a first RF detector circuit and a reverse output signal to a second RF detector circuit; and an analog-to-digital converter that receives an output of the RF detector circuits and provides a corresponding converted
    Type: Grant
    Filed: March 9, 2011
    Date of Patent: April 3, 2018
    Assignee: Profound Medical, Inc.
    Inventors: Cameron Mahon, Nicolas Yak, Rajiv Chopra, Mathew Asselin, Michael Bronskill
  • Publication number: 20170204149
    Abstract: The disclosure relates to fusion polypeptides comprising serum albumin or a functional variant thereof and GDF15 protein or a functional variant thereof and to pharmaceutical compositions that contain the fusion polypeptides, nucleic acids that encode the fusion polypeptides, methods of making the polypeptides and use of the polypeptides to decreasing appetite, decreasing body weight and treating metabolic diseases.
    Type: Application
    Filed: June 19, 2015
    Publication date: July 20, 2017
    Applicant: NOVARTIS AG
    Inventors: Rajiv CHOPRA, Norio HAMAMATSU, Ryan Scott STREEPER, Brian Edward VASH
  • Patent number: 9707413
    Abstract: An apparatus is disclosed for thermal therapy in a male prostate patient. The apparatus includes, in preferred embodiments, a long tubular element that is to be inserted into a patient's urethra so that a first tip end of it reaches up into the patient's diseased prostate. The elongated portion includes a narrow cylindrical tube within which an ultrasonic array is disposed along the long axis of the cylinder. Fluid is pumped into and out of a treatment zone of said patient as needed to control a temperature of a region in said treatment zone. A motorized driver is used to controllably rotate said elongated portion and the ultrasound array therein about the long axis of the apparatus so as to deliver acoustic energy to said diseased tissue. Various control and monitoring components may be used in conjunction with the present apparatus to design, control, and terminate the therapy.
    Type: Grant
    Filed: March 9, 2011
    Date of Patent: July 18, 2017
    Assignee: Profound Medical Inc.
    Inventors: Rajiv Chopra, Sean Donaldson, Cameron Mahon
  • Publication number: 20160067527
    Abstract: A focused ultrasound (“FUS”} system capable of use in a small bore imaging system, such as a small bore magnetic resonance imaging (“MRI”} system is provided. The FUS system generally includes an ultrasound transducer whose position is adjusted by a positioning system. The positioning system is sized to fit within the bore of the small bore imaging system. For instance, the positioning system can fit within a diameter of 150 millimeters or less.
    Type: Application
    Filed: April 14, 2014
    Publication date: March 10, 2016
    Inventors: Kullervo HYNYNEN, Anthony CHAU, Rajiv CHOPRA
  • Patent number: 9101752
    Abstract: A focused ultrasound system includes an ultrasound transducer configured to emit focused ultrasound energy toward a subject and a positioning system configured to position the ultrasound transducer to localize the focused ultrasound energy within a target location. The positioning system includes a drive apparatus to translate the ultrasound transducer along at least one axis of motion and a motor controller to control the drive apparatus. The focused ultrasound system also includes a control system connected to the motor controller that is programmed to receive imaging/location data from an imaging system, determine positional coordinates of the target location based on the imaging/location data, and register the positional coordinates of the target location with the positioning system. The positional coordinates are sent to the motor controller via an input signal to cause the motor controller to control the drive apparatus so as to translate the ultrasound transducer.
    Type: Grant
    Filed: November 16, 2009
    Date of Patent: August 11, 2015
    Assignee: SUNNYBROOK HEALTH SCIENCES CENTRE
    Inventors: Rajiv Chopra, Kullervo Hynynen, Anthony Chau, Adam Christian Waspe
  • Patent number: 9032085
    Abstract: Techniques are described for identifying the use of software applications, such as to determine an identity of a user interacting with a Web site or other electronic information service based on information regarding an application copy used by the user. When a communication is received from a software application, the communication is analyzed to attempt to identify a particular software application copy that sent the communication. Various types of information about a client software application copy may be used in the analysis, including information about particular configuration settings for the client software application and for the client computing device on which the client software application is executing. After a matching software application copy is identified for a received communication, possible inappropriate activities related to the received communication may be identified in various ways, including based on previous communications received from the same software application copy.
    Type: Grant
    Filed: November 27, 2013
    Date of Patent: May 12, 2015
    Assignee: Amazon Technologies, Inc.
    Inventors: Richendra Khanna, Weijiang Yu, Rajiv Chopra
  • Patent number: 8989838
    Abstract: The present invention provides a method and apparatus for delivering and controlling thermal therapy to a volume of diseased tissue. Specifically, the invention includes using thermal imaging and other inputs to determine an acoustic (ultrasonic) treatment regime employing interstitial ultrasound applicators to deliver a required therapeutic temperature or thermal dose to the affected region in a body or organ. Various aspects of the treatment that can be controlled include individual transducer element operating power and frequency, as well as the rate of cooling and rotation of the entire applicator.
    Type: Grant
    Filed: July 6, 2010
    Date of Patent: March 24, 2015
    Assignee: Sunnybrook Health Sciences Centre
    Inventors: Rajiv Chopra, Michael Bronskill, Mathieu Burtnyk
  • Publication number: 20140246914
    Abstract: A power distribution system comprising a point of common connection that receives electric power supplied by a first power generation system and a second generation system, with the second power generation system that comprises a renewable electric power generator; a transmission line operatively connected to the point of common connection for conducting the electric power between the point of common connection and an external AC electric network. The power distribution furthermore comprises a capacitive compensator connected in series with the transmission line to compensate for a reactive power component of the electric power conducted by the transmission line; and a shunt arranged flexible AC transmission system that mitigates a sub-synchronous resonance effect caused at least in part by the capacitive compensator. A flexible AC transmission system controller of the flexible AC transmission system comprises a damping effect on sub-synchronous oscillations included in the sub-synchronous resonance.
    Type: Application
    Filed: September 12, 2012
    Publication date: September 4, 2014
    Applicant: ALSTOM TECHNOLOGY LTD.
    Inventors: Rajiv Chopra, Reginald Mendis, Marek Furyk
  • Patent number: 8801701
    Abstract: The invention provides a method and apparatus for monitoring a thermal effect of a conformal thermal treatment to diseased tissue in a target volume. The method includes acquiring a reference image of the volume containing the diseased tissue at a first position of the device, determining a baseline temperature distribution of the reference image, acquiring an image of the volume containing the diseased tissue while delivering a treatment to the volume, performing a phase subtraction between the image and the reference image to determine a change in phase between the image and the reference image and determining a current spatial temperature distribution in the volume containing the diseased tissue.
    Type: Grant
    Filed: March 27, 2007
    Date of Patent: August 12, 2014
    Assignee: Sunnybrook Health Sciences Centre
    Inventors: Rajiv Chopra, Michael Bronskill, Kee Tang
  • Patent number: 8626935
    Abstract: Techniques are described for identifying the use of software applications, such as to determine an identity of a user interacting with a Web site or other electronic information service based on information regarding an application copy used by the user. When a communication is received from a software application, the communication is analyzed to attempt to identify a particular software application copy that sent the communication. Various types of information about a client software application copy may be used in the analysis, including information about particular configuration settings for the client software application and for the client computing device on which the client software application is executing. After a matching software application copy is identified for a received communication, possible inappropriate activities related to the received communication may be identified in various ways, including based on previous communications received from the same software application copy.
    Type: Grant
    Filed: September 15, 2012
    Date of Patent: January 7, 2014
    Assignee: Amazon Technologies, Inc.
    Inventors: Richendra Khanna, Weijiang Yu, Rajiv Chopra
  • Patent number: 8423467
    Abstract: Financial transactions, such as buying and selling, may be facilitated by merchant-based shadow account numbers. A master account may contain several associated shadow accounts. Each shadow account may in turn be associated with a specific merchant or group of merchants. Merchants and users may store and use the shadow account numbers rather than the master account numbers. Stolen or otherwise compromised shadow account numbers are useless with other non-associated merchants. Furthermore, the shadow numbers may be easily invalidated while leaving the master account untouched.
    Type: Grant
    Filed: March 8, 2010
    Date of Patent: April 16, 2013
    Inventors: Jesper M. Johansson, David H. Hijirida, Peter S. Vosshall, Rajiv Chopra, Terrance Douglas Hanold
  • Patent number: 8324239
    Abstract: The present invention provides a compound of formula I; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
    Type: Grant
    Filed: April 19, 2011
    Date of Patent: December 4, 2012
    Assignee: Novartis AG
    Inventors: David Barnes, Rajiv Chopra, Scott Louis Cohen, Jiping Fu, Mitsunori Kato, Peichao Lu, Mohindra Seepersaud, Wei Zhang
  • Patent number: 8307099
    Abstract: Techniques are described for identifying the use of software applications, such as to determine an identity of a user interacting with a Web site or other electronic information service based on information regarding an application copy used by the user. When a communication is received from a software application, the communication is analyzed to attempt to identify a particular software application copy that sent the communication. Various types of information about a client software application copy may be used in the analysis, including information about particular configuration settings for the client software application and for the client computing device on which the client software application is executing. After a matching software application copy is identified for a received communication, possible inappropriate activities related to the received communication may be identified in various ways, including based on previous communications received from the same software application copy.
    Type: Grant
    Filed: December 19, 2006
    Date of Patent: November 6, 2012
    Assignee: Amazon Technologies, Inc.
    Inventors: Richendra Khanna, Weijiang Yu, Rajiv Chopra
  • Patent number: 8222901
    Abstract: A system and method for intracorporeal elastography include an intra-luminal vibratory member configured to be positioned within a lumen of an imaging subject and configured to impart mechanical energy into tissue of the lumen. In a preferred embodiment, an external piezoelectric energy source is included and coupled to the vibratory member and configured to cause the vibratory member to longitudinally vibrate, thereby generating shear waves for use with magnetic resonance elastography.
    Type: Grant
    Filed: August 20, 2009
    Date of Patent: July 17, 2012
    Assignee: Sunnybrook Health Sciences Centre
    Inventors: Rajiv Chopra, Michael John Bronskill, Arvin Forghanian-Arani
  • Publication number: 20120015907
    Abstract: The present invention provides a compound of formula I; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
    Type: Application
    Filed: April 19, 2011
    Publication date: January 19, 2012
    Applicant: NOVARTIS AG
    Inventors: David BARNES, Rajiv CHOPRA, Scott Louis COHEN, Jiping FU, Mitsunori Kato, Peichao LU, Mohindra SEEPERSAUD, Wei ZHANG