Abstract: A method, article of manufacture, and apparatus for accessing a distributed file system using a content delivery network is discussed. An IO request for an object is received at a metadata server comprising metadata mapping a plurality of objects to an object store. An object identifier associated with the object and a CDN domain associated with the object store are determined. A URL is generated from the object identifier and the CDN domain. The URL is then returned to the client.

Abstract: Techniques to provide secure cloud-based storage of data shared across file system objects and clients are disclosed. In various embodiments, a primary encryption key is determined for an object associated with a plurality of component chunks of file system data. The primary encryption key is used to generate for each of said component chunks a corresponding chunk key, based at least in part on the primary encryption key and data comprising or otherwise associated with the chunk. The respective chunk keys are provided to a file system client configured to create and store the object at least in part by encrypting each chunk included in the plurality of component chunks using the chunk key provided for that chunk to generated encrypted chunk data, and combining the encrypted chunk data to create and store the object.

Abstract: Techniques to provide access to file system information are disclosed. In various embodiments, an indication that a user input associated with creating a local copy of a file system object has been received is received at a file system client. The file system client determines that a user-driven pre-fetch option has been set with respect to the file system object. The file system client pre-fetches content data associated with the file system object, based at least in part on the determination that the pre-fetch option has been set with respect to the file system object.

Abstract: The conjugate compositions and methods are useful to elicit/augment an immune response to a tumor or microbial infection or to reduce the severity of autoimmunity, chronic inflammation, allergy, asthma, periodontal disease, and transplant rejection.

Abstract: Techniques to provide secure cloud-based storage of data shared across file system objects and clients are disclosed. In various embodiments, a primary encryption key is determined for an object associated with a plurality of component chunks of file system data. The primary encryption key is used to generate for each of said component chunks a corresponding chunk key, based at least in part on the primary encryption key and data comprising or otherwise associated with the chunk. The respective chunk keys are provided to a file system client configured to create and store the object at least in part by encrypting each chunk included in the plurality of component chunks using the chunk key provided for that chunk to generated encrypted chunk data, and combining the encrypted chunk data to create and store the object.

Abstract: The present disclosure provides click-crosslinked hydrogels and methods of use.

Abstract: The present invention provides refillable drug delivery devices. The invention is based in part on the development of systemically administered drug payloads that home to and refill resident, e.g., previously administered/implanted, drug delivery systems, e.g., hydrogel drug delivery systems. In one aspect, the drug delivery depots of the invention are systemically administered, e.g., enterally administered or parenterally administered. The invention provides a method of nanotherapeutic drug delivery, e.g., a DNA nanotechnology-based approach for blood-based drug refilling of intra-tumor drug depots.

Abstract: Techniques to provide a de-duplicating distributed file system using a cloud-based object store are disclosed. In various embodiments, a request to store a file comprising a plurality of chunks of file data is received. A determination to store at least a subset of the plurality of chunks is made. The request is responded to at least in part by providing an indication to store two or more chunks comprising the at least a subset of the plurality of chunks comprising the file as a single stored object that includes the combined chunk data of said two or more chunks.

Abstract: Techniques to provide secure cloud-based storage of data shared across file system objects and clients are disclosed. In various embodiments, a primary encryption key is determined for an object associated with a plurality of component chunks of file system data. The primary encryption key is used to generate for each of said component chunks a corresponding chunk key, based at least in part on the primary encryption key and data comprising or otherwise associated with the chunk. The respective chunk keys are provided to a file system client configured to create and store the object at least in part by encrypting each chunk included in the plurality of component chunks using the chunk key provided for that chunk to generated encrypted chunk data, and combining the encrypted chunk data to create and store the object.

Abstract: The present invention provides refillable drug delivery systems, as well as methods of refilling the systems, and methods of using them to treat diseases.

Abstract: The present invention provides refillable drug delivery systems, as well as methods of refilling the systems, and methods of using them to treat diseases.

Abstract: An approach for concurrently running multiple kernels using a common interrupt handler and an optional common scheduler is provided. Techniques are also provided to switch execution among the kernels. Execution and interrupt preemption among kernels in shown using interrupt mask levels. Techniques are also provided for the sharing of resources between tasks running on different kernels.