Abstract: A guidewire management device, a method of manufacturing the guidewire management device and a method for guidewire management are disclosed. The guidewire management device includes a housing through which a lumen of a catheter passes; and a locking mechanism mounted within the housing; wherein the locking mechanism is configured to lock the housing if a guidewire is present in the lumen and to unlock the housing if the guidewire is absent from the lumen. In one embodiment, the locking mechanism comprises a lever structure comprising a first arm connected to a second arm, wherein the first arm is configured to abut the lumen such that it becomes displaceable from a first position to a second position and actuates the second arm to engage a latch member to lock the housing if the guidewire is inserted through the lumen. Conversely, the housing unlocks if the guidewire is removed from the lumen.