Abstract: The present invention describes the development of a novel, tumor epithelial cell and tumor-associated macrophage (TAM)-targeting, blood brain barrier (BBB) crossing glucose-based nanospheres (CSP). More specifically, the present invention discloses a nanoformulation and/or a composition having anticancer activity comprising of carbon nanosphere (CSP) and a sigma receptor targeting ligand (H8) in the ratio of 1:0.08 to 1:0.2, a complex prepared thereof, a process for preparation thereof and a kit for delivery of the drug molecule or the formulation or the composition to tumor site.

Abstract: A robotic manipulator includes one or multiple end effectors that can engage with an object, and one or multiple cameras that simultaneously observe each end effector, and the surrounding environment. For example, an end effector can include a contact surface including tactile markers which can deform when the end effector contacts the object.

Abstract: A robotic manipulator is described. The robotic manipulator includes a rigid or semi-rigid end effector that engages with objects and a sensor that detects data associated with the object. For example, the sensor can include an optical sensor or a vision-based tactile sensor that detects data associated with the object.