Patents by Inventor Rajni Jani

Rajni Jani has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • AQUEOUS PHARMACEUTICAL COMPOSITIONS CONTAINING BORATE-POLYOL COMPLEXES
    Publication number: 20140294750
    Abstract: The present invention is directed to the provision of multi-dose, ophthalmic compositions. The compositions possess sufficient antimicrobial activity to satisfy USP preservative efficacy requirements, as well as similar preservative standards (e.g., EP and JP). The compositions include at two different polyols in conjunction with borate, a preservative or both.
    Type: Application
    Filed: June 13, 2014
    Publication date: October 2, 2014
    Inventors: Bhagwati P. Kabra, Rajni Jani
  • Olopatadine formulations for topical nasal administration
    Patent number: 8399508
    Abstract: Topical formulations of olopatadine for treatment of allergic or inflammatory disorders of the nose are disclosed. The aqueous formulations contain approximately 0.6% (w/v) of olopatadine.
    Type: Grant
    Filed: June 30, 2011
    Date of Patent: March 19, 2013
    Assignee: Alcon Pharmaceuticals Ltd.
    Inventors: Onkar N. Singh, G. Michael Wall, Rajni Jani, Masood A. Chowhan, Wesley Wehsin Han
  • OLOPATADINE FORMULATIONS FOR TOPICAL NASAL ADMINISTRATION
    Publication number: 20110306659
    Abstract: Topical formulations of olopatadine for treatment of allergic or inflammatory disorders of the nose are disclosed. The aqueous formulations contain approximately 0.6% (w/v) of olopatadine.
    Type: Application
    Filed: June 30, 2011
    Publication date: December 15, 2011
    Applicant: Novartis AG
    Inventors: Onkar N. Singh, G. Michael Wall, Rajni Jani, Masood A. Chowhan, Wesley Wehsin Han
  • Olopatadine formulations for topical nasal administration
    Patent number: 7977376
    Abstract: Topical formulations of olopatadine for treatment of allergic or inflammatory disorders of the nose are disclosed. The aqueous formulations contain approximately 0.6% (w/v) of olopatadine.
    Type: Grant
    Filed: February 7, 2007
    Date of Patent: July 12, 2011
    Assignee: Novartis AG
    Inventors: Onkar N. Singh, G. Michael Wall, Rajni Jani, Masood A. Chowhan, Wesley Wehsin Han
  • AQUEOUS PHARMACEUTICAL COMPOSITIONS CONTAINING BORATE-POLYOL COMPLEXES
    Publication number: 20090232763
    Abstract: The present invention is directed to the provision of multi-dose, ophthalmic compositions. The compositions possess sufficient antimicrobial activity to satisfy USP preservative efficacy requirements, as well as similar preservative standards (e.g., EP and JP). The compositions include at two different polyols in conjunction with borate, a preservative or both.
    Type: Application
    Filed: March 3, 2009
    Publication date: September 17, 2009
    Inventors: Bhagwati P. Kabra, Rajni Jani
  • USE OF STEROIDS TO TREAT PERSONS SUFFERING FROM OCULAR DISORDERS
    Publication number: 20090181933
    Abstract: Methods and compositions for treating retinal edema and NPDR are disclosed.
    Type: Application
    Filed: January 11, 2008
    Publication date: July 16, 2009
    Inventors: David P. Bingaman, Abbot F. Clark, Rajni Jani, Stella M. Robertson
  • Self-Preserved Ophthalmic Pharmaceutical Compositions Containing Tobramycin
    Publication number: 20080089953
    Abstract: Self-preserved, multi-dose ophthalmic compositions containing tobramycin are described. The compositions do not contain a conventional antimicrobial preservative, such as benzalkonium chloride. Rather, the compositions are self-preserved as a result of the inherent antimicrobial activity of tobramycin. The compositions preferably also contain either boric acid or, more preferably, a borate/polyol complex selected from the group consisting of borate/propylene glycol, borate/glycerol, and combinations thereof.
    Type: Application
    Filed: December 12, 2007
    Publication date: April 17, 2008
    Applicant: ALCON, INC.
    Inventors: Masood Chowhan, Ernesto Castillo, Glenn Stafford, Rajni Jani, Haresh Bhagat
  • PHARMACEUTICAL FORMULATION FOR DELIVERY OF RECEPTOR TYROSINE KINASE INHIBITING (RTKi) COMPOUNDS TO THE EYE
    Publication number: 20070173538
    Abstract: The present invention relates to development of efficacious pharmaceutical compositions comprising a poorly water soluble active compound in a therapeutically effective amount and a co-solvent in a suitable amount to treat or prevent diseases due to ocular neovascularization and enhanced vascular permeability. In preferred aspects the composition is in the form of a gel.
    Type: Application
    Filed: December 20, 2006
    Publication date: July 26, 2007
    Applicant: Alcon, Inc.
    Inventors: Wesley Han, Rajni Jani, Huixiang Zhang
  • Olopatadine formulations for topical nasal administration
    Publication number: 20070142458
    Abstract: Topical formulations of olopatadine for treatment of allergic or inflammatory disorders of the nose are disclosed. The aqueous formulations contain approximately 0.6% (w/v) of olopatadine.
    Type: Application
    Filed: February 7, 2007
    Publication date: June 21, 2007
    Inventors: Onkar Singh, G. Wall, Rajni Jani, Masood Chowhan, Wesley Han
  • Use of steroids to treat ocular disorders
    Publication number: 20060154910
    Abstract: Methods and compositions for treating retinal edema and NPDR are disclosed.
    Type: Application
    Filed: February 4, 2004
    Publication date: July 13, 2006
    Inventors: David Bingaman, Abbot Clark, Rajni Jani, Stella Robertson
  • Self-preserved ophthalmic pharmaceutical compositions containing tobramycin
    Publication number: 20060141059
    Abstract: Self-preserved, multi-dose ophthalmic compositions containing tobramycin are described. The compositions do not contain a conventional antimicrobial preservative, such as benzalkonium chloride. Rather, the compositions are self-preserved as a result of the inherent antimicrobial activity of tobramycin. The compositions preferably also contain either boric acid or, more preferably, a borate/polyol complex selected from the group consisting of borate/propylene glycol, borate/glycerol, and combinations thereof.
    Type: Application
    Filed: December 23, 2005
    Publication date: June 29, 2006
    Inventors: Masood Chowhan, Ernesto Castillo, Glenn Stafford, Rajni Jani, Haresh Bhagat
  • Formulations of glucocorticoids to treat pathologic ocular angiogenesis
    Publication number: 20060074061
    Abstract: Formulations of glucocorticoids alone and in combination with anecortave acetate are useful for preventing and treating pathologic ocular angiogenesis and associated edema
    Type: Application
    Filed: February 5, 2004
    Publication date: April 6, 2006
    Inventors: David Bingaman, Abbot Clark, Rajni Jani, Stella Robertson
  • Triamcinolone acetonide and anecortave acetate formulations for injection
    Publication number: 20050065137
    Abstract: Injectable compositions of triamcinolone acetonide or anecortave acetate are disclosed. The compositions are particularly suitable for injection into the posterior segment of the eye to treat ophthalmic diseases.
    Type: Application
    Filed: September 2, 2004
    Publication date: March 24, 2005
    Inventors: Rajni Jani, Ernesto Castillo, Wesley Han
  • Use of steroids to treat persons suffering from ocular disorders
    Publication number: 20040171598
    Abstract: Methods and compositions for treating retinal edema and NPDR are disclosed.
    Type: Application
    Filed: February 4, 2004
    Publication date: September 2, 2004
    Inventors: David P. Bingaman, Abbot F. Clark, Rajni Jani, Stella M. Robertson
  • Formulations of glucocorticoids to treat pathologic ocular angiogenesis
    Publication number: 20040167109
    Abstract: Formulations of glucocorticoids alone and in combination with anecortave acetate are useful for preventing and treating pathologic ocular angiogenesis and associated edema.
    Type: Application
    Filed: February 5, 2004
    Publication date: August 26, 2004
    Inventors: David P. Bingaman, Abbot F. Clark, Rajni Jani, Stella M. Robertson
  • Use of an anti-allergy agent and a steroid to treat nasal conditions
    Publication number: 20040097474
    Abstract: Compositions and methods for treating rhinitis with certain combinations of antiallergic agents and steroids are disclosed.
    Type: Application
    Filed: November 12, 2003
    Publication date: May 20, 2004
    Applicant: Alcon, Inc.
    Inventors: Gerald D. Cagle, G. Michael Wall, John M. Yanni, Rajni Jani, Haresh G. Bhagat
  • Antibacterial compositions
    Patent number: 5679336
    Abstract: Aqueous pharmaceutical compositions containing a synergistic combination of a quinolone and a polystyrene sulfonic acid polymer are described, wherein the compositions are clear solutions which are comfortable and have sustained release. Methods for use of the compositions are also disclosed. This type of formulation is particularly useful with ciprofloxacin-type quinolones by greatly increasing the solubility of these quinolones, making it feasible to have aqueous solutions containing such quinolones at or near physiological pH.
    Type: Grant
    Filed: October 18, 1995
    Date of Patent: October 21, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Yusuf Ali, Rajni Jani
  • Sustained release comfort formulation for glaucoma therapy
    Patent number: 5635172
    Abstract: Disclosed are nonstinging, sustained release ophthalmic formulations to control intraocular pressure in antiglaucoma therapy comprising a basic active, a cation exchange resin, and, inter alia, an acidic, mucomimetic polymer. Also disclosed are methods of treatment comprising administering such formulations topically to the eye when indicated for control and lowering of intraocular pressure.
    Type: Grant
    Filed: February 27, 1995
    Date of Patent: June 3, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Rajni Jani, Robert G. Harris
  • Topical ophthalmic carbonic anhydrase inhibitor formulations
    Patent number: 5620970
    Abstract: The present invention is directed to topical ophthalmic formulations of carbonic anhydrase inhibitors and polyethoxylated derivatives of castor oil. Methods for using the formulations for treating and controlling glaucoma and ocular hypertension are also disclosed.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: April 15, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Wesley W. Han, Thomas R. Dean, Steven H. Gerson, Yusuf Ali, Rajni Jani
  • Compositions for treatment of glaucoma
    Patent number: 5554367
    Abstract: Compositions for controlling glaucoma and ocular hypertension are disclosed.
    Type: Grant
    Filed: November 4, 1994
    Date of Patent: September 10, 1996
    Assignee: Alcon Laboratories, Inc.
    Inventors: Yusuf Ali, Rajni Jani, George R. McCarty