Patents by Inventor Rajnish Kaushik

Rajnish Kaushik has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of transducing non-dividing myeloid cells utilizing chimeric murine leukemia viruses containing Vpx
    Patent number: 9023648
    Abstract: The invention is directed to a chimeric gammaretrovirus comprising an gammaretroviral virion which contains a lentiviral Vpx protein and methods of use thereof. In a particular aspect, the chimeric gammaretrovirus is a chimeric murine leukemia virus (MLV) comprising an MLV virion which contains a lentiviral Vpx protein. The invention is also directed to use of the chimeric gammaretrovirus to produce a MLV that can transduce a non-dividing cell (G1/S/G2), transduce a non-dividing cell; enhance the ability of a MLV to transduce a non-dividing cell; transduce a quiescent (G0) cell; and enhance the ability of a human immunodeficiency virus 1 (HIV-1) to transduce a quiescent (G0) cell.
    Type: Grant
    Filed: December 29, 2010
    Date of Patent: May 5, 2015
    Assignee: University of Massachusetts
    Inventors: Mario Stevenson, Rajnish Kaushik, Xiaonan Zhu
  • CHIMERIC GAMMARETROVIRUS
    Publication number: 20110165683
    Abstract: The invention is directed to a chimeric gammaretrovirus comprising an gammaretroviral virion which contains a lentiviral Vpx protein and methods of use thereof.
    Type: Application
    Filed: December 29, 2010
    Publication date: July 7, 2011
    Applicant: University of Massachusetts
    Inventors: Mario Stevenson, Rajnish Kaushik, Xiaonan Zhu