Patents by Inventor Raju Mohan

Raju Mohan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ROR-GAMMA MODULATORS
    Publication number: 20210069182
    Abstract: Described herein are retinoic acid related-related orphan nuclear receptor (ROR) modulators and methods of utilizing ROR? modulators in the treatment of dermal diseases, disorders or conditions. Also described herein are pharmaceutical compositions containing such compounds.
    Type: Application
    Filed: November 23, 2020
    Publication date: March 11, 2021
    Inventors: Raju MOHAN, John NUSS, Jason HARRIS
  • BICYCLIC ROR-GAMMA MODULATORS
    Publication number: 20210053987
    Abstract: Described herein are retinoic acid related-related orphan nuclear receptor (ROR) modulators and methods of utilizing ROR-gamma modulators in the treatment of diseases, disorders or conditions. Also described herein are pharmaceutical compositions containing such compounds.
    Type: Application
    Filed: March 11, 2019
    Publication date: February 25, 2021
    Inventors: Raju MOHAN, John NUSS, Jason HARRIS, Shendong YUAN
  • SPIROCYCLIC ROR-GAMMA MODULATORS
    Publication number: 20210053976
    Abstract: Described herein are retinoic acid related-related orphan nuclear receptor (ROR) modulators and methods of utilizing NROR-gamma modulators in the treatment of diseases, disorders or conditions. Also described herein are pharmaceutical compositions containing such compounds.
    Type: Application
    Filed: March 11, 2019
    Publication date: February 25, 2021
    Inventors: Raju MOHAN, John NUSS, Jason HARRIS, Shendong YUAN
  • JAK INHIBITORS
    Publication number: 20210040100
    Abstract: Described herein are Janus kinase (JAK) inhibitors and methods of utilizing JAK inhibitors in the treatment of diseases, disorders or conditions. Also described herein are pharmaceutical compositions containing such compounds.
    Type: Application
    Filed: August 7, 2020
    Publication date: February 11, 2021
    Inventors: Raju MOHAN, John NUSS, Jason HARRIS, Shendong YUAN
  • Substituted piperazines as ROR-gamma modulators
    Patent number: 10905687
    Abstract: Described herein are retinoic acid related-related orphan nuclear receptor (ROR) modulators of Formula (I) and pharmaceutical compositions thereof, and methods of utilizing these ROR? modulators in the treatment of dermal diseases, disorders or conditions: Amendment to the abstract of disclosure showing mark-up: Described herein are retinoic acid related-related orphan nuclear receptor (ROR) modulators of Formula (I) and pharmaceutical compositions thereof, and methods of utilizing these ROR? modulators in the treatment of dermal diseases, disorders or conditions:
    Type: Grant
    Filed: October 27, 2017
    Date of Patent: February 2, 2021
    Assignee: ESCALIER BIOSCIENCES B.V.
    Inventors: Raju Mohan, John Nuss, Jason Harris
  • FUSED BICYCLIC COMPOUNDS
    Publication number: 20200407364
    Abstract: Described herein are fused bicyclic compounds, compositions, and methods for their preparation.
    Type: Application
    Filed: July 14, 2020
    Publication date: December 31, 2020
    Inventors: Raju Mohan, Benjamin Anthony Pratt
  • COMBINATION THERAPIES WITH FARNESOID X RECEPTOR (FXR) MODULATORS
    Publication number: 20200397798
    Abstract: Described herein are methods of treating a metabolic disorder in an individual in need thereof, comprising co-administering to the individual a therapeutically effective amount of an FXR modulator, and at least one second agent that is an CCR2/CCR5 antagonist, ASK1 inhibitor, DPP-IV inhibitor, caspase protease inhibitor, SGLT2 inhibitor, acetyl-CoA carboxylase (ACC) inhibitor, diacylglycerol acyltransferase-1 inhibitor, sodium-bile acid cotransporter-inhibitor, TLR-4 antagonist, PPAR alpha/delta agonist, or GLP-1 agonist, or a combination thereof.
    Type: Application
    Filed: May 25, 2017
    Publication date: December 24, 2020
    Applicant: Akarna Therapeutics, Ltd.
    Inventors: Raju MOHAN, Benjamin Anthony PRATT
  • JAK INHIBITORS
    Publication number: 20200369669
    Abstract: Described herein are Janus kinase (JAK) inhibitors and methods of utilizing JAK inhibitors in the treatment of diseases, disorders or conditions. Also described herein are pharmaceutical compositions containing such compounds.
    Type: Application
    Filed: May 7, 2020
    Publication date: November 26, 2020
    Inventors: Raju MOHAN, John NUSS, Jason HARRIS, Shendong YUAN
  • HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF DISEASE
    Publication number: 20200325135
    Abstract: Described herein are heterocyclic compounds, compositions, and methods for their use for the treatment of disease.
    Type: Application
    Filed: May 1, 2020
    Publication date: October 15, 2020
    Inventors: Raju MOHAN, John NUSS, Jason HARRIS
  • FUSED BICYCLIC COMPOUNDS FOR THE TREATMENT OF DISEASE
    Publication number: 20200325140
    Abstract: Described herein are fused bicyclic compounds, compositions, and methods for their use for the treatment of disease.
    Type: Application
    Filed: May 25, 2017
    Publication date: October 15, 2020
    Applicant: Akarna Therapeutics, Ltd.
    Inventors: Raju MOHAN, Benjamin Anthony PRATT
  • Fused bicyclic compounds for the treatment of disease
    Patent number: 10793577
    Abstract: Described herein are fused bicyclic compounds, compositions, and methods for their use for the treatment of disease.
    Type: Grant
    Filed: December 31, 2018
    Date of Patent: October 6, 2020
    Assignee: Akarna Therapeutics, Ltd.
    Inventors: Raju Mohan, Benjamin Anthony Pratt
  • Heterocyclic compounds for the treatment of disease
    Patent number: 10683291
    Abstract: Described herein are heterocyclic compounds, compositions, and methods for their use for the treatment of disease.
    Type: Grant
    Filed: November 11, 2016
    Date of Patent: June 16, 2020
    Assignee: OPPILAN PHARMA LTD.
    Inventors: Raju Mohan, John Nuss, Jason Harris
  • FUSED BICYCLIC COMPOUNDS FOR THE TREATMENT OF DISEASE
    Publication number: 20200079782
    Abstract: Described herein are fused bicyclic compounds, compositions, and methods for their use for the treatment of disease.
    Type: Application
    Filed: September 19, 2019
    Publication date: March 12, 2020
    Applicant: AKARNA THERAPEUTICS, LTD.
    Inventors: Raju MOHAN, Benjamin Anthony PRATT
  • Prodrugs for the Treatment of Disease
    Publication number: 20200071327
    Abstract: Described herein are prodrugs of heterocyclic compounds, compositions, and methods for their use for the treatment of disease.
    Type: Application
    Filed: May 16, 2018
    Publication date: March 5, 2020
    Inventors: Raju MOHAN, John NUSS, Jason HARRIS
  • FUSED BICYCLIC COMPOUNDS FOR THE TREATMENT OF DISEASE
    Publication number: 20190308977
    Abstract: Described herein are fused bicyclic compounds, compositions, and methods for their use for the treatment of disease.
    Type: Application
    Filed: March 15, 2019
    Publication date: October 10, 2019
    Inventors: Benjamin Anthony PRATT, Raju MOHAN
  • Fused bicyclic compounds for the treatment of disease
    Patent number: 10421759
    Abstract: Described herein are fused bicyclic compounds, compositions, and methods for their use for the treatment of disease.
    Type: Grant
    Filed: September 25, 2017
    Date of Patent: September 24, 2019
    Assignee: AKARNA THERAPEUTICS, LTD.
    Inventors: Raju Mohan, Benjamin Anthony Pratt
  • ROR-GAMMA MODULATORS
    Publication number: 20190269674
    Abstract: Described herein are retinoic acid related-related orphan nuclear receptor (ROR) modulators and methods of utilizing ROR? modulators in the treatment of dermal diseases, disorders or conditions. Also described herein are pharmaceutical compositions containing such compounds.
    Type: Application
    Filed: October 27, 2017
    Publication date: September 5, 2019
    Applicant: ESCALIER BIOSCIENCES, BV
    Inventors: Raju Mohan, John Nuss, Jason Harris
  • HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF DISEASE
    Publication number: 20190241556
    Abstract: Described herein are heterocyclic compounds, compositions, and methods for their use for the treatment of disease.
    Type: Application
    Filed: November 11, 2016
    Publication date: August 8, 2019
    Inventors: Raju MOHAN, John NUSS, Jason HARRIS
  • FUSED BICYCLIC COMPOUNDS FOR THE TREATMENT OF DISEASE
    Publication number: 20190211026
    Abstract: Described herein are fused bicyclic compounds, compositions, and methods for their use for the treatment of disease.
    Type: Application
    Filed: December 31, 2018
    Publication date: July 11, 2019
    Inventors: Raju Mohan, Benjamin Anthony Pratt
  • LIVER X RECEPTOR (LXR) MODULATORS
    Publication number: 20190169131
    Abstract: Described herein are liver X receptor (LXR) modulators and methods of utilizing LXR modulators in the treatment of LXR-associated diseases, disorders or conditions. Also described herein are pharmaceutical compositions containing such compounds.
    Type: Application
    Filed: February 6, 2019
    Publication date: June 6, 2019
    Inventor: Raju MOHAN