Abstract: A method of operating a remote navigation system to that orients a medical device in a selected direction includes operating the remote navigation system to orient the medical device toward a point identified by the user on a two-dimensional map of a three-dimensional surface adjacent the medical device.

Abstract: A method and apparatus for Magnetic Resonance Imaging with specialized imaging coils possessing high Signal-to-Noise-Ratio (SNR). Imaging and/or Radio Frequency receiving coils include a ballistic electrical conductor such as carbon nanotubes, the ballistic electrical conductor having a resistance that does not increase significantly with length. Due to their enhanced SNR properties, system designs with smaller static magnetic field strength can be constructed for the same quality of imaging, leading to substantial reductions in system size and cost, as well as to enhanced imaging with existing MRI systems.

Abstract: A method and apparatus for Magnetic Resonance Imaging with specialized imaging coils possessing high Signal-to-Noise-Ratio (SNR). Imaging and/or Radio Frequency receiving coils include a ballistic electrical conductor such as carbon nanotubes, the ballistic electrical conductor having a resistance that does not increase significantly with length. Due to their enhanced SNR properties, system designs with smaller static magnetic field strength can be constructed for the same quality of imaging, leading to substantial reductions in system size and cost, as well as to enhanced imaging with existing MRI systems.

Abstract: A method for controlling a remote navigation system includes operating the remote navigation system to bring a sensor carried on a medical device successively into a plurality of locations in a predetermined pattern, and using the sensor to sense a physiological property in each location. At least once thereafter, the remote navigation system is operated to bring a sensor carried on a medical device successively into a series of locations in a predetermined pattern relative to at least one location selected from the predetermined pattern in the immediately preceding step based upon the sensed physiological property value, and uses the sensor to sense the physiological property in each location. A local extreme value of the sensed physiological property is thereby located. The physiological properties that can be sensed include electrical signals, conductivity, temperature, fluid flow rate or fluid velocity, and range of motion of a surface.

Abstract: An integrated control and display system for operating a plurality of separate computer systems each having a visual display, includes at least one cursor control device for seamlessly moving a cursor among the visual displays of the separate computer systems, the cursor control device operating to control the computer system associated with the display on which the cursor appears.

Abstract: An apparatus is disclosed for Magnetic Resonance Imaging with specialized imaging coils possessing high Signal-to-Noise-Ratios (SNR). Radio Frequency transmitting and/or Radio Frequency receiving elements include carbon nanotube material, a ballistic electrical conductor having a resistance that does not increase significantly with length. The shapes of the receiving and transmitting elements can be linear, curvilinear, or coiled. The carbon nanotube material can be layered. Due to their enhanced SNR properties, preferred embodiments have smaller static magnetic field strengths with imaging quality comparable to known field systems, leading to substantial reductions in system size and cost. Other preferred embodiments provide enhanced imaging with known MRI static magnetic field strengths.

Abstract: A method for determining a transformation of a three-dimensional pre-operative image data set to obtain a registration of the three-dimensional image data with an X-ray imaging system. In one aspect of the present invention, the method comprises the steps of the user identifying a center point and extreme contour points of the object from an X-ray image, obtaining a set of contour points for the image object in each of a plurality of section-planes, and selecting from a sampling of section-planes the points projecting nearest to the user-identified extreme points. The method then defines a grid having a predetermined number of intervals at a predetermined interval spacing with the grid center at the user-identified center of the pre-operative image, and performs a projection of the center point of the three-dimensional image data set onto each grid point for evaluation and selection of the grid point projecting nearest to the user-identified center.

Abstract: An interface system and method for controlling a magnetic surgery system by displaying a virtual image of the device, adjusting the configuration of the device or the actuation controls to be applied to the device until the configuration of the displayed device assumes the configuration desired by the user, or selecting a desired target location for the tip, and causing a set of actuation controls to be applied to the actual device to cause the actual device to assume the configuration of the virtual device or to steer the device tip to the desired location.

Abstract: A method of operating a navigation system that can orient the distal end of a medical device in a selected direction to navigate the medical device through a network of body lumens in an operating region in a subject that includes identifying a path through the network of body lumens in the operating region; displaying a two-dimensional image of the operating region including the path through the body lumens; determining at least one location on the path; and operating the navigation system to orient the distal end of the medical device in a direction substantially aligned with the path at the at least one location and advancing the distal end of the medical device.

Abstract: A method for determining a translation of a three-dimensional pre-operative image data set to obtain a registration of the three-dimensional image data with a patient positioned in a projection imaging system. In one embodiment the user identifies an initial three-dimensional organ center from projections and extreme contour landmark points of the object on a set of projections. A set of contour points for the image object in each of a plurality of three-dimensional cross-section planes; is obtained and the points projecting nearest to the user-identified landmark points are selected. A three-dimensional grid having a predetermined number of intervals at a predetermined interval spacing centered at the user-identified organ center is defined. The three-dimensional image data contour points as centered onto each grid point are projected for evaluation and selection of the grid point leading to contour points projecting nearest to the user-identified landmark points.

Abstract: An integrated control and display system for operating a plurality of separate computer systems each having a visual display, includes at least one cursor control device for seamlessly moving a cursor among the visual displays of the separate computer systems, the cursor control device operating to control the computer system associated with the display on which the cursor appears.

Abstract: A method and apparatus are disclosed for Magnetic Resonance Imaging using specialized signal acquisition and processing techniques for image reconstruction with a generally inhomogeneous static magnetic field. New signal processing methods for image reconstruction and for minimizing dephasing effects are disclosed. Imaging systems with smaller static magnetic field strengths and smaller hardware demands than those with homogeneous static magnetic fields are provided, leading to significant reductions in system size and cost as compared to standard MRI systems. Such systems can also exploit imaging coils having high Signal-to-Noise-Ratio (SNR), including those made from Carbon nanotube conductors, leading to further imaging system efficiencies.

Abstract: A method of determining the quality of contact between a remotely navigated medical device and a cyclically moving anatomical structure includes measuring movement of the device, and processing the measured movement of the device to determine the contact between the device and the moving anatomical structure.

Abstract: A system for navigating a medical device through the lumens and cavities in an operating region in a subject, comprising an imaging system for displaying an image of the operating region, including a representation of the distal end of the medical device in the operating region. The system also includes a localization system for determining the position of the medical device in a frame of reference translatable to the displayed image. Finally, the system includes an algorithm for evaluating one or more rotation matrix using a cost function to determine an optimum rotation matrix for performing transformation of a vector in the local frame of the localization system to that of the reference frame of the navigation system. The rotation matrix can then provide a scale invariant transformation or “registration” of the coordinate systems of the localization system and the navigation system.

Abstract: An interface for remotely controlling a medical device in a patient's body provides a two dimensional display of a three dimensional rendering of the operating region, and allows the user to select the orientation or location of the distal end of the medical device on the display and then operate a navigation system to cause the distal end of the medical device to approximately assume the selected orientation or location.

Abstract: An interface for remotely controlling a medical device in a patient's body provides a two dimensional display of a three dimensional rendering of the operating region, and allows the user to select the orientation or location of the distal end of the medical device on the display and then operate a navigation system to cause the distal end of the medical device to approximately assume the selected orientation or location.

Abstract: An interface for remotely controlling a medical device in a patient's body provides a two dimensional display of a three dimensional rendering of the operating region, and allows the user to select the orientation or location of the distal end of the medical device on the display and then operate a navigation system to cause the distal end of the medical device to approximately assume the selected orientation or location.

Abstract: This invention describes an energy delivery apparatus for delivering electrical energy at a target location, said energy delivery apparatus being usable in combination with a magnetic field and comprising an electrical conductor having a substantially elongated configuration; an electrode for delivering electrical energy at the target location, with the electrode being electrically coupled to the electrical conductor and having an exposed surface with at least a portion of the exposed surface having one of its principal radii of curvature smaller than 0.35 mm; an insulating dielectric coating along a substantial portion of the length of the electrical conductor, with the dielectric coating having a dielectric constant smaller than about 3; at least one guiding element mounted to the electrical conductor, with at least one of the guiding elements including a magnetically responsive material.

Abstract: This invention describes an occlusion crossing apparatus for creating an opening in occluded tissue at a target location in interventional and surgical applications with simultaneous or nearly simultaneous intravascular imaging.

Abstract: Devices for the generation and detection of an ablative plasma discharge in a subject are presented. Methods of use, including navigation and operation of the devices to facilitate minimally invasive therapeutic procedures are disclosed.