Patents by Inventor Raju S. Chaganti

Raju S. Chaganti has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of analyzing chromosomal translocations using fluorescence in situ hybridization (FISH)
    Patent number: 7964345
    Abstract: Probes and methods of using the probes to detect chromosomal rearrangements and/or deletions are provided. The methods utilize probes that are free of repeat sequences to provide greater selectivity and sensitivity; methods for producing such probes are also disclosed. The probe sets utilized in the detection methods are designed to hybridize to chromosomes at regions outside known breakpoints, instead of spanning the breakpoint as with conventional FISH methods, and, in some instances, are further designed to bind to regions located outside the genes involved in the rearrangement. Methods utilizing probe sets with two and four colors are also described, as are automated methods for analyzing rearrangements.
    Type: Grant
    Filed: April 5, 2005
    Date of Patent: June 21, 2011
    Assignee: Cancer Genetics, Inc.
    Inventors: Nallasivam Palanisamy, Raju S. Chaganti
  • Methods of analyzing chromosomal translocations using fluorescence in situ hybridization (FISH)
    Patent number: 7585964
    Abstract: Probes and methods of using the probes to detect chromosomal rearrangements and/or deletions are provided. The methods utilize probes that are free of repeat sequences to provide greater selectivity and sensitivity; methods for producing such probes are also disclosed. The probe sets utilized in the detection methods are designed to hybridize to chromosomes at regions outside known breakpoints, instead of spanning the breakpoint as with conventional FISH methods, and, in some instances, are further designed to bind to regions located outside the genes involved in the rearrangement. Methods utilizing probe sets with two and four colors are also described, as are automated methods for analyzing rearrangements.
    Type: Grant
    Filed: May 14, 2002
    Date of Patent: September 8, 2009
    Assignee: Cancer Genetics, Inc.
    Inventors: Nallasivam Palanisamy, Raju S. Chaganti
  • Methods of analyzing chromosomal translocations using fluorescence in situ hybridization (FISH)
    Publication number: 20020192692
    Abstract: Probes and methods of using the probes to detect chromosomal rearrangements and/or deletions are provided. The methods utilize probes that are free of repeat sequences to provide greater selectivity and sensitivity; methods for producing such probes are also disclosed. The probe sets utilized in the detection methods are designed to hybridize to chromosomes at regions outside known breakpoints, instead of spanning the breakpoint as with conventional FISH methods, and, in some instances, are further designed to bind to regions located outside the genes involved in the rearrangement. Methods utilizing probe sets with two and four colors are also described, as are automated methods for analyzing rearrangements.
    Type: Application
    Filed: May 14, 2002
    Publication date: December 19, 2002
    Applicant: Cancer Genetics, Inc.
    Inventors: Nallasivam Palanisamy, Raju S. Chaganti