Patents by Inventor Rajvir Dahiya

Rajvir Dahiya has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10801072
    Abstract: A multi-gene-based assay for analysis of the following: (a) oncogene expression; (b) DNA methylation of tumor suppressor genes; (c) non-coding RNA expression (microRNA profiling); and (d) long non-coding RNA expression in cancer samples is disclosed. The assay method and device for conducting the assay are applicable to diagnosis, prognosis, and treatment of various cancers such as lung, breast, colorectal, prostate, liver, bladder; kidney, cervix, pancreatic, gastric, brain, oral, endometrium, and ovary. The assay methods allow avoidance of surgery to remove cancerous tissue.
    Type: Grant
    Filed: September 3, 2015
    Date of Patent: October 13, 2020
    Assignee: MIODx
    Inventors: Rajvir Dahiya, M. Allen Northrup
  • Publication number: 20170275702
    Abstract: A multi-gene-based assay for analysis of the following: (a) oncogene expression; (b) DNA methylation of tumor suppressor genes; (c) non-coding RNA expression (microRNA profiling); and (d) long non-coding RNA expression in cancer samples is disclosed. The assay method and device for conducting the assay are applicable to diagnosis, prognosis, and treatment of various cancers such as lung, breast, colorectal, prostate, liver, bladder; kidney, cervix, pancreatic, gastric, brain, oral, endometrium, and ovary. The assay methods allow avoidance of surgery to remove cancerous tissue.
    Type: Application
    Filed: September 3, 2015
    Publication date: September 28, 2017
    Applicant: MIODx
    Inventors: Rajvir DAHIYA, M. Allen NORTHRUP
  • Publication number: 20170233825
    Abstract: A multi-gene-based assay for analysis of the following: (a) oncogene expression; (b) DNA methylation of tumor suppressor genes; (c) non-coding RNA expression (microRNA profiling); and (d) long non-coding RNA expression in cancer samples is disclosed. The assay method and device for conducting the assay are applicable to diagnosis, prognosis, and treatment of various cancers such as lung, breast, colorectal, prostate, liver, bladder; kidney, cervix, pancreatic, gastric, brain, oral, endometrium, and ovary. The assay methods find use in avoidance or postponement of surgical removal of cancer tissue.
    Type: Application
    Filed: September 3, 2015
    Publication date: August 17, 2017
    Applicant: MIODx
    Inventors: Rajvir DAHIYA, M. Allen NORTHRUP
  • Patent number: 9297008
    Abstract: The present invention provides compositions, pharmaceutical preparations, kits and methods for increasing expression of a gene product in a cell by contacting the cell with a small activating RNA (saRNA) molecule comprising a ribonucleic strand that is complementary to a non-coding nucleic acid sequence of the gene.
    Type: Grant
    Filed: October 1, 2014
    Date of Patent: March 29, 2016
    Assignee: The Regents of the University of California
    Inventors: Longcheng Li, Rajvir Dahiya
  • Publication number: 20150104869
    Abstract: The present invention provides compositions, pharmaceutical preparations, kits and methods for increasing expression of a gene product in a cell by contacting the cell with a small activating RNA (saRNA) molecule comprising a ribonucleic strand that is complementary to a non-coding nucleic acid sequence of the gene.
    Type: Application
    Filed: October 1, 2014
    Publication date: April 16, 2015
    Inventors: Longcheng Li, Rajvir Dahiya
  • Patent number: 8877721
    Abstract: The present invention provides compositions, pharmaceutical preparations, kits and methods for increasing expression of a gene product in a cell by contacting the cell with a small activating RNA (saRNA) molecule comprising a ribonucleic strand that is complementary to a non-coding nucleic acid sequence of the gene.
    Type: Grant
    Filed: April 11, 2006
    Date of Patent: November 4, 2014
    Assignee: The Regents of the University of California
    Inventors: Longcheng Li, Rajvir Dahiya
  • Publication number: 20110054012
    Abstract: The present invention provides compositions, pharmaceutical preparations, kits and methods for increasing expression of a gene product in a cell by contacting the cell with a microRNA (miRNA) molecule comprising a ribonucleic strand that is complementary to a non-coding nucleic acid sequence of the gene.
    Type: Application
    Filed: December 23, 2008
    Publication date: March 3, 2011
    Inventors: Robert F. Place, Long-Cheng Li, Rajvir Dahiya
  • Publication number: 20100210707
    Abstract: The present invention provides compositions, pharmaceutical preparations, kits and methods for increasing expression of a gene product in a cell by contacting the cell with a small activating RNA (saRNA) molecule comprising a ribonucleic strand that is complementary to a non-coding nucleic acid sequence of the gene.
    Type: Application
    Filed: April 11, 2006
    Publication date: August 19, 2010
    Inventors: Longcheng Li, Rajvir Dahiya
  • Patent number: 7306627
    Abstract: Acellular matrix grafts are provided with are isolated from natural sources and consist essentially of a collagen and elastin matrix which is devoid of cellular components. The grafts are useful scaffolds which promote the regeneration of muscle tissue and aid in restoring muscle function. Due to their acellular nature, the grafts lack antigenicity. As a result, the acellular matrix grafts can be isolated from autographic, allographic or xenographic tissues.
    Type: Grant
    Filed: January 18, 2002
    Date of Patent: December 11, 2007
    Assignee: The Regents of the University of California
    Inventors: Emil A. Tanagho, Rajvir Dahiya, Tom F. Lue, Gerald R. Cunha
  • Publication number: 20020128711
    Abstract: Acellular matrix grafts are provided with are isolated from natural sources and consist essentially of a collagen and elastin matrix which is devoid of cellular components. The grafts are useful scaffolds which promote the regeneration of muscle tissue and aid in restoring muscle function. Due to their acellular nature, the grafts lack antigenicity. As a result, the acellular matrix grafts can be isolated from autographic, allographic or xenographic tissues.
    Type: Application
    Filed: January 18, 2002
    Publication date: September 12, 2002
    Applicant: The Regents of the University of California
    Inventors: Emil A. Tanagho, Rajvir Dahiya, Tom F. Lue, Gerald R. Cunha
  • Patent number: 6371992
    Abstract: Acellular matrix grafts are provided with are isolated from natural sources and consist essentially of a collagen and elastin matrix which is devoid of cellular components. The grafts are useful scaffolds which promote the regeneration of muscle tissue and aid in restoring muscle function. Due to their acellular nature, the grafts lack antigenicity. As a result, the acellular matrix grafts can be isolated from autographic, allographic or xenographic tissues.
    Type: Grant
    Filed: December 19, 1997
    Date of Patent: April 16, 2002
    Assignee: The Regents of the University of California
    Inventors: Emil A. Tanagho, Rajvir Dahiya, Tom F. Lue, Gerald R. Cunha
  • Patent number: 5656478
    Abstract: The present invention provides a method of growing smooth muscle cells in a host with the purpose of maintaining natural cellular function by the function of smooth muscle tissue. In this method, smooth muscle cells are freed from isolated smooth muscle tissue then cultured and injected into the host in combination with an extracellular matrix.
    Type: Grant
    Filed: February 25, 1994
    Date of Patent: August 12, 1997
    Assignee: The Regents of the University of California
    Inventors: Emil A. Tanagho, Rajvir Dahiya, Tom F. Lue, Gerald R. Cunha