Patents by Inventor Rakesh K. Tyagi

Rakesh K. Tyagi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Estrogen receptor site-specific ribozymes and uses thereof for estrogen dependent tumors
    Patent number: 7179593
    Abstract: Highly specific hammerhead ribozymes are provided that human target estrogen receptor mRNA. These ribozymes, designated RZ1 through RZ7 provide predictable mRNA cleavage products. Methods for inhibiting estrogen-dependent tumor growth, such as that characteristic of breast cancer, are also provided employing these ribozymes. One or both of the ribozymes may be used together or separately with equal efficiency. The ribozymes possess a sequence region with a catalytic core that provides the attributed catalytic activity to these ribozymes.
    Type: Grant
    Filed: June 2, 2000
    Date of Patent: February 20, 2007
    Assignee: Board of Regents, The University of Texas System
    Inventors: Arun K. Roy, Yan Lavrovsky, Rakesh K. Tyagi, Chung S. Song, Bandana Chatterjee, Shuo Chen