Patents by Inventor Rakesh Kamal Johri
Rakesh Kamal Johri has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9085559Abstract: A novel heterocyclic compound belonging to ‘triazine-aryl-bis-indoles’, useful for the treatment of asthma. The pathway by which this compound inhibits asthma is also demonstrated. The present invention also provides a process for the preparation of above compounds and their derivatives are presented.Type: GrantFiled: December 31, 2010Date of Patent: July 21, 2015Assignee: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCHInventors: Vasanta Madhava Sharma Gangavaram, Jhillu Singh Yadav, Radha Krishna Palakodety, Arun Bandyopadhyay, Siddhartha Roy, Santu Bandyopadhyay, Rakesh Kamal Johri, Subhash Chander Sharma, Balaram Ghosh, Mabalirajan Ulaganathan, Sakshi Balwani, Bholanath Paul, Ashok Kumar Saxena
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Patent number: 9073860Abstract: The present invention relates to an aromatic substituted pentadienoic acid amides and there use in combination of specific amounts of aromatic amides i.e. 4-alkyl-5-(substituted phenyl)-2 (E),4(E)-pentadienoic acid amides, its geometrical isomers or their dihydro or tetrahydro derivatives and an anti-infective drug useful in potentiating the bioefficacy of antiinfective drug. The combination of the present invention is useful in the treatment of certain infections and disease at lower concentration of anti-infectives necessary to inhibit the growth of microbial strains and may also find applications in reducing the resistance in microorganisms.Type: GrantFiled: October 11, 2013Date of Patent: July 7, 2015Assignee: COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCHInventors: Surrinder Koul, Jawahir Lal Koul, Subhash Chandra Taneja, Pankaj Gupta, Inshad Ali Khan, Zahid Mehmood Mirza, Ashwani Kumar, Rakesh Kamal Johri, Monika Pandita, Anita Khosa, Ashok Kumar Tikoo, Subhash Chander Sharma, Vijeshwar Verma, Ghulam Nabi Qazi
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Publication number: 20140073595Abstract: The present invention relates to an aromatic substituted pentadienoic acid amides and there use in combination of specific amounts of aromatic amides i.e. 4-alkyl-5-(substituted phenyl)-2(E),4(E)-pentadienoic acid amides, its geometrical isomers or their dihydro or tetrahydro derivatives and an anti-infective drug useful in potentiating the bioefficacy of antiinfective drug. The combination of the present invention is useful in the treatment of certain infections and disease at lower concentration of anti-infectives necessary to inhibit the growth of microbial strains and may also find applications in reducing the resistance in microorganisms.Type: ApplicationFiled: October 11, 2013Publication date: March 13, 2014Applicant: Council Of Scientific and Industrial ResearchInventors: Surrinder KOUL, Jawahir Lal KOUL, Subhash Chandra TANEJA, Pankaj GUPTA, Inshad Ali KHAN, Zahid Mehmood MIRZA, Ashwani KUMAR, Rakesh Kamal JOHRI, Monika PANDITA, Anita KHOSA, Ashok Kumar TIKOO, Subhash Chander Sharma, Vijeshwar VERMA, Ghulam Nabi QAZI
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Patent number: 8580752Abstract: The present invention relates to an aromatic substituted pentadienoic acid amides and there use in combination of specific amounts of aromatic amides i.e. 4-alkyl-5-(substituted phenyl)-2(E),4(E)-pentadienoic acid amides, its geometrical isomers or their dihydro or tetrahydro derivatives and an anti-infective drug useful in potentiating the bioefficacy of antiinfective drug. The combination of the present invention is useful in the treatment of certain infections and disease at lower concentration of anti-infectives necessary to inhibit the growth of microbial strains and may also find applications in reducing the resistance in microorganisms.Type: GrantFiled: March 29, 2006Date of Patent: November 12, 2013Assignee: Council of Scientitic and Industrial ResearchInventors: Surrinder Koul, Jawahir Lal Koul, Subhash Chandra Taneja, Pankaj Gupta, Inshad Ali Khan, Zahid Mehmood Mirza, Ashwani Kumar, Rakesh Kamal Johri, Monika Pandita, Anita Khosa, Ashok Kumar Tikoo, Subhash Chander Sharma, Vijeshwar Verma, Ghulam Nabi Qazi
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Patent number: 8519154Abstract: The present invention relates to a method for the treatment of bronchial asthma and chronic obstructive pulmonary disease (COPD) comprising administering to the patient suffering from asthma and COPD an effective dose of carbazole derivatives or salt thereof, optionally along with pharmaceutically acceptable excipients. Structural formula of the compounds of general formula 1 useful as phosphodiesterase-4 (PDE-4) enzyme inhibitors, inhibitor for signalling molecule for the treatment of asthma and asthma related diseases is given below: wherein R1=H or OCH3; R2?CH3 or CHO; R3?H or OCH3; R4?H or OCH3 Herbal route for the isolation of compound of general formula 1 from the bark of plant Murraya Koenigii and chemical route for the preparation of such compounds from basic compounds such as vanillin is also reported.Type: GrantFiled: February 3, 2012Date of Patent: August 27, 2013Assignee: Council of Scientific & Industrial ResearchInventors: Sibabrata Mukhopadhyay, Mumu Chakraborty, Tulika Mukherjee, Arun Bandyopadhyay, Dipak Kar, Tanima Banerjee, Aditya Konar, Debaprasad Jana, Siddhartha Roy, Santu Bandyopadhyay, Balram Ghosh, Mabalirajan Ulaganathan, Rakesh Kamal Johri, Subhash Chander Sharma, Gurdarshan Singh, Bholanath Paul, Vasanta Madhava Sharma Gangavaram, Jhillu Singh Yadav, Radha Krishna Palakodety
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Publication number: 20120283263Abstract: A novel heterocyclic compound belonging to ‘triazine-aryl-bis-indoles’, useful for the treatment of asthma. The pathway by which this compound inhibits asthma is also demonstrated. The present invention also provides a process for the preparation of above compounds and their derivatives are presented.Type: ApplicationFiled: December 31, 2010Publication date: November 8, 2012Applicant: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCHInventors: Vasanta Madhava Sharma Gangavaram, Jhillu Singh Yadav, Radha Krishna Palakodety, Arun Bandyopadhyay, Siddhartha Roy, Santu Bandyopadhyay, Rakesh Kamal Johri, Subhash Chander Sharma, Balaram Ghosh, Mabalirajan Ulaganathan, Sakshi Balwani, Bholanath Paul, Ashok Kumar Saxena
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Publication number: 20120202868Abstract: The present invention relates to a method for the treatment of bronchial asthma and chronic obstructive pulmonary disease (COPD) comprising administering to the patient suffering from asthama and COPD an effective dose of carbazole derivatives or salt thereof, optionally along with pharmaceutically acceptable excipients. Structural formula of the compounds of general formula 1 useful as phosphodiesterase-4 (PDE-4) enzyme inhibitors, inhibitor for signalling molecule for the treatment of asthma and asthma related diseases is given below: wherein R1=H or OCH3; R2?CH3 or CHO; R3?H or OCH3; R4?H or OCH3 Herbal route for the isolation of compound of general formula 1 from the bark of plant Murraya Koenigii and chemical route for the preparation of such compounds from basic compounds such as vanillin is also reported.Type: ApplicationFiled: February 3, 2012Publication date: August 9, 2012Applicant: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCHInventors: Sibabrata MUKHOPADHYAY, Mumu CHAKRABORTY, Tulika MUKHERJEE, Arun BANDYOPADHYAY, Dipak KAR, Tanima BANERJEE, Aditya KONAR, Debaprasad JANA, Siddhartha ROY, Santu BANDYOPADHYAY, Balram GHOSH, Mabalirajan ULAGANATHAN, Rakesh Kamal JOHRI, Subhash Chander SHARMA, Gurdarshan SINGH, Bholanath PAUL, Vasanta Madhava Sharma GANGAVARAM, Jhillu Singh YADAV, Radha Krishna PALAKODETY
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Patent number: 7514105Abstract: The present invention relates to a bioenhancing/bioavailability-facilitating composition comprising: an effective amount of an extract and/or at least one bioactive fraction from Cuminum cyminum; one or more additive selected from drugs, nutrients, vitamins, nutraceuticals, herbal drugs/products, micro nutrients, antioxidants along with pharmaceuticaly acceptable additives/excipient, and optionally, an effective amount of piperine or extract/fraction of piper nigrum or piper longum; and a process for the preparation of such extracts and active fractions from plant Cuminum cyminum.Type: GrantFiled: February 23, 2006Date of Patent: April 7, 2009Assignee: Council of Scientific and Industrial ResearchInventors: Ghulam Nabi Qazi, Kasturi Lal Bedi, Rakesh Kamal Johri, Manoj Kumar Tikoo, Ashok Kumar Tikoo, Subhash Chander Sharma, Sheikh Tasaduq Abdullah, Om Parkash Suri, Bishan Datt Gupta, Krishan Avtar Suri, Naresh Kumar Satti, Ravi Kant Khajuria, Surjit Singh, Anamika Khajuria, Bal Krishan Kapahi
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Publication number: 20080292736Abstract: The present invention relates to the use of extracts of Carum carvi as bioenhancers, either alone or in combination with piperine or Zingiber officinale extract to improve the bioavailability of a wide variety of drugs.Type: ApplicationFiled: January 28, 2008Publication date: November 27, 2008Inventors: Ghulam Nabi Qazi, Kasturi Lal Bedi, Rakesh Kamal Johri, Manoj Kumar Tikoo, Ashok Kumar Tikoo, Subhash Chandra Sharma, Tasaduaq Abdullah, Om Parkash Suri, Bishan Datt Gupta, Krishan Avtar Suri, Naresh Kumar Satti, Ravi Kant Khajuria
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Publication number: 20080138452Abstract: The present invention relates to a composition useful for hepatocurative effect against CYP 450 bio-activation hepatotoxicity induced by drugs, said composition comprising an extract from Emblica officinalis and optionally pharmaceutically acceptable additives and method of treating drug induced hepatotoxicityType: ApplicationFiled: December 21, 2007Publication date: June 12, 2008Inventors: Rakesh Kamal Johri, Sheikh Tasaduq Abdullah, Kuldeep Singh, Devinder Kumar Gupta, Bal Krishan Kapahi, Dilip Manikrao Mondhe, Satinder Mohan Jain, Om Parkash Suri, Kasturi Lal Bedi, Ghulam Nabi Qazi
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Patent number: 7259148Abstract: The present invention provides a method for treating and/or preventing hepatic disease conditions in a subject mammals including human beings, said method comprising the steps of administering to the mammal an effective dosage of composition comprising 2?-p-Hydroxy benzoyl mussaenosidic acid from plant Vitex negundo optionally as individual or in combination with one or more pharmaceutically additives.Type: GrantFiled: May 12, 2003Date of Patent: August 21, 2007Assignee: Council of Scientific & Industrial ResearchInventors: Anil Prabhakar, Bishan Datt Gupta, Krishan Avtar Suri, Naresh Kumar Satti, Swadesh Malhotra, Kuldip Kumar Gupta, Vijay Kumar Sharma, Rakesh Kamal Johri, Bupinder Singh Jaggi, Bal Krishan Chandan, Shankar Lal, Kasturi Lal Bedi, Om Parkash Suri, Gulam Nabi Qazi
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Patent number: 7119075Abstract: The present invention relates to the use of bioenhancers to decrease the resistance of microbial strains to anti-infective such an antibiotics and antifungals by potentiating the activities of anti-infective. This may be useful to reduce resistance in bacteria and yeast to aid in the treatment of certain infections and disease and to lower the concentration of antiinfectives necessary to inhibit the growth of microbial strains.Type: GrantFiled: March 31, 2003Date of Patent: October 10, 2006Assignee: Council of Scientific and Industrial ResearchInventors: Ghulam Nabi Qazi, Om Parkash Suri, Kasturi Lal Bedi, Inshad Ali Khan, Vijeshwar Verma, Rakesh Kamal Johri, Krishan Avtar Suri, Bishan Datt Gupta, Naresh Kumar Satti, Manoj Kumar Tikoo, Subhash Chander Sharma, Ashok Kumar Tikoo
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Patent number: 7070814Abstract: The present invention relates to a bioenhancing/bioavailability-facilitating composition comprising: an effective amount of an extract and/or at least one bioactive fraction from Cuminum cyminum; one or more additive selected from drugs, nutrients, vitamins, nutraceuticals, herbal drugs/products, micro nutrients, antioxidants along with pharmaceutically acceptable additives/excipient, and optionally, an effective amount of piperine or extract/fraction of piper nigrum or piper longum; and a process for the preparation of such extracts and active fractions from plant Cuminum cyminum.Type: GrantFiled: March 11, 2003Date of Patent: July 4, 2006Assignee: Council of Scientific and Industrial ResearchInventors: Ghulam Nabi Qazi, Kasturi Lal Bedi, Rakesh Kamal Johri, Manoj Kumar Tikoo, Ashok Kumar Tikoo, Subhash Chander Sharma, Sheikh Tasaduq Absullah, Om Parkash Suri, Bishan Datt Gupta, Krishan Avtar Suri, Naresh Kumar Satti, Ravi Kant Khajuria, Surjit Singh, Anamika Khajuria, Bal Krishan Kapahi
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Patent number: 7001619Abstract: The present invention relates to a composition useful for hepatocurative effect against CYP 450 bio-activation hepatotoxicity induced by drugs, said composition comprising an extract from Emblica officinalis and optionally pharmaceutically acceptable additives and method of treating drug induced hepatotoxicity.Type: GrantFiled: March 27, 2002Date of Patent: February 21, 2006Assignee: Council of Scientific and Industrial ResearchInventors: Rakesh Kamal Johri, Sheikh Tasaduq Abdullah, Kuldeep Singh, Devinder Kumar Gupta, Bal Krishan Kapahi, Dilip Manikrao Mondhe, Satinder Mohan Jain, Om Parkash Suri, Kasturi Lal Bedi, Ghulam Nabi Qazi
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Publication number: 20040198672Abstract: The present invention relates to the use of bioenhancers to decrease the resistance of microbial strains to anti-infective such an antibiotics and antifungals by potentiating the activities of anti-infective. This may be usefuil to reduce resistance in bacteria and yeast to aid in the treatment of certain infections and disease and to lower the concentration of antiinfectives necessary to inhibit the growth of microbial strains.Type: ApplicationFiled: March 31, 2003Publication date: October 7, 2004Applicant: COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCHInventors: Ghulam Nabi Qazi, Om Parkash Suri, Kasturi Lal Bedi, Inshad Ali Khan, Vijeshwar Verma, Rakesh Kamal Johri, Krishan Avtar Suri, Bishan Datt Gupta, Naresh Kumar Satti, Manoj Kumar Tikoo, Subhash Chander Sharma, Ashok Kumar Tikoo
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Publication number: 20040121028Abstract: The invention relates to the isolation and preparation of an active fraction from plant Cuminum cyminum, its further purification and standardization as chemically defined entity (ies) with their intended use as drug bioavailability enhancer for the drugs belonging to therapeutic categories such as antimicrobial, antifungal, anti-viral, antitubercular, antileprosy, anti-inflammatory, antiarthritic, cardiovascular, antihistaminics, respiratory distress relieving drugs, immunosuppressants, anti-ulcerogenic, anti-cancer, CNS drugs, corticosteroids, nutraceuticals in compositions to be administered orally/parenterally, topically, inhalations (including nebulizers), rectally, vaginally in human beings and/or veterinary conditions.Type: ApplicationFiled: July 16, 2003Publication date: June 24, 2004Applicant: COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCHInventors: Ghulam Nabi Qazi, Kasturi Lal Bedi, Rakesh Kamal Johri, Subhash Chander Sharma, Manoj Kumar Tikoo, Ashok Kumar Tikoo, Sheikh Tasaduq Abdullah, Kuldip Singh, Rashmi Pandita, Om Parkash Suri, Bishan Datt Gupta, Krishan Avtar Suri, Naresh Kumar Satti, Ravi Kant Khajuria, Bal Krishan Kapahi, Ashok Kumar Kalsotra, Neelam Verma, Rajneesh Anand
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Publication number: 20040052873Abstract: The present invention relates to a bioenhancing/bioavailability-facilitating composition comprising:Type: ApplicationFiled: March 11, 2003Publication date: March 18, 2004Applicant: COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCHInventors: Ghulam Nabi Qazi, Kasturi Lal Bedi, Rakesh Kamal Johri, Manoj Kumar Tickoo, Ashok Kumar Tickoo, Subhash Chander Sharma, Sheikh Tasaduq Abdullah, Om Parkash Suri, Bishan Datt Gupta, Krishan Avtar Suri, Naresh Kumar Satti, Ravi Kant Khajuria, Surjit Singh, Anamika Khajuria, Bal Krishan Kapahi
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Publication number: 20040029816Abstract: A method for treating and/or preventing hepatic disease conditions in mammals including human beings, said method comprising the steps of administering to the mammal an effective amount of 10-O-p-hydroxybenzoylaucubin compound of Formula 1, also called Agnuside, optionally individual or in combination with one or more pharmaceutically acceptable additives.Type: ApplicationFiled: May 12, 2003Publication date: February 12, 2004Inventors: Anil Prabhakar, Bishan Datt Gupta, Krishan Avtar Suri, Naresh Kumar Satti, Swadesh Malhotra, Rakesh Kamal Johri, Bupinder Singh Jaggi, Bal Krishan Chandan, Ashok Kumar Sharma, Devinder Kumar Gupta, Bal Krishan Kapahi, Kasturi Lal Bedi, Om Parkash Suri, Gulam Nabi Qazi
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Publication number: 20040014684Abstract: The present invention provides a method for treating and/or preventing hepatic disease conditions in a subject mammals including human beings, said method comprising the steps of administering to the mammal an effective dosage of composition comprising 2′-p-Hydroxy benzoyl mussaenosidic acid from plant Vitex negundo optionally as individual or in combination with one or more pharmaceutically additives.Type: ApplicationFiled: May 12, 2003Publication date: January 22, 2004Inventors: Anil Prabhakar, Bishan Datt Gupta, Krishan Avtar Suri, Naresh Kumar Satti, Swadesh Malhotra, Kuldip Kumar Gupta, Vijay Kumar Sharma, Rakesh Kamal Johri, Bupinder Singh Jaggi, Bal Krishan Chandan, Shankar Lal, Kasturi Lal Bedi, Om Parkash Suri, Gulam Nabi Qazi
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Publication number: 20030228381Abstract: The present invention relates to the use of extracts of Carum carvi as bioenhancers, either alone or in combination with piperine or Zinzeber officinale extract to improve the bioavailability of a wide variety of drugs.Type: ApplicationFiled: February 10, 2003Publication date: December 11, 2003Applicant: COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCHInventors: Ghulam Nabi Qazi, Kasturi Lal Bedi, Rakesh Kamal Johri, Manoj Kumar Tikoo, Ashok Kumar Tikoo, Subhash Chandra Sharma, Tasaduaq Abdullah, Om Parkash Suri, Bishan Datt Gupta, Krishan Avtar Suri, Naresh Kumar Satti, Ravi Kant Khajuria