Patents by Inventor Rakesh Mendhe

Rakesh Mendhe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROCESS FOR THE PREPARATION OF GUANYLATE CYCLASE 2C AGONIST
    Publication number: 20190055278
    Abstract: The present invention relates to an improved process for the preparation of Linaclotide of Formula I. The process disclosed in the present invention is simple, economical and eco-friendly with reduced reaction times.
    Type: Application
    Filed: February 3, 2017
    Publication date: February 21, 2019
    Inventors: Dharmaraj Ramachandra RAO, Geena MALHOTRA, Venkata Srinivas PULLELA, Parag Shankar KURLE, Rakesh MENDHE
  • Process for the production of macrolides using a novel strain, sp. BICC 7522
    Patent number: 8012723
    Abstract: The present invention discloses a new strain of Streptomyces sp. BICC 7522, its variants or mutants and use of the strain for the production of macrolides, process of production and purification of macrolides.
    Type: Grant
    Filed: January 12, 2010
    Date of Patent: September 6, 2011
    Assignee: Biocon, Ltd.
    Inventors: Madhav Kulkarni, Surekha K. Prabhu, Madenahally Channabasappa Shivakumar, Prijyajit Sengupta, Sanjay Tiwari, Rakesh Mendhe, Nitin Patil, Laxmi Adhikary, Anand Khedkar, Ramakrishnan Melarkode, Ramavana Gururaja, Shrikumar Suryanarayan
  • PROCESS FOR THE PRODUCTION OF MACROLIDES USING A NOVEL STRAIN, STREPTOMYCES SP. BICC 7522
    Publication number: 20100184985
    Abstract: The present invention discloses a new strain of Streptomyces sp. BICC 7522, its variants or mutants and use of the strain for the production of macrolides, process of production and purification of macrolides.
    Type: Application
    Filed: January 12, 2010
    Publication date: July 22, 2010
    Applicant: Biocon, Ltd.
    Inventors: Madhav Kulkarni, Surekha K. Prabhu, Madenahally Channabasappa Shivakumar, Prijyajit Sengupta, Sanjay Tiwari, Rakesh Mendhe, Nitin Patil, Laxmi Adhikary, Anand Khedkar, Ramakrishnan Melarkode, Ramavana Gururaja, Shrikumar Suryanarayan
  • Process for the production of macrolides using a novel strain, sp. BICC 7522
    Patent number: 7704725
    Abstract: The present invention discloses a new strain of Streptomyces sp. BICC 7522, its variants or mutants and use of the strain for the production of macrolides, process of production and purification of microlides.
    Type: Grant
    Filed: April 12, 2004
    Date of Patent: April 27, 2010
    Assignee: Biocon Limited
    Inventors: Madhav Kulkarni, Surekha K. Prabhu, Madenahally Channabasappa Shivakumar, Prijyajit Sengupta, Sanjay Tiwari, Rakesh Mendhe, Nitin Patil, Laxmi Adhikary, Anand Khedkar, Ramakrishnan Melarkode, Ramavana Gururaja, Shrikumar Suryanarayan
  • Process for the purification of macrolides
    Patent number: 7473366
    Abstract: The invention relates to a process for the recovery of a macrolide in substantial pure form including: a) treating an impure or crude macrolide with water immiscible solvent to form a mixture, b) optionally concentrating the mixture, c) treating with ammonia gas to phase out impurities, d) separating impurities, e) optionally concentrating a phase containing the macrolide, f) loading on silica gel chromatography, optionally reversed phase or pretreated with silver, and eluting the macrolide, g) affording the macrolide in the substantially pure form, h) optional repetition of steps f and g to afford the macrolide in the substantially pure form. The macrolide is preferably tacrolimus, immunomycin or sirolimus.
    Type: Grant
    Filed: December 5, 2003
    Date of Patent: January 6, 2009
    Assignee: BioCon Limited
    Inventors: Nitin Sopanrao Patil, Rakesh Mendhe, Anand Prakash Khedkar, Ramakrishnan Melarkode, Ramavana Gururaja
  • Process for the Production of Macrolides Using a Novel Strain, Streptomyces Sp. Bicc 7522
    Publication number: 20080286842
    Abstract: The present invention discloses a new strain of Streptomyces sp. BICC 7522, its variants or mutants and use of the strain for the production of macrolides, process of production and purification of microlides.
    Type: Application
    Filed: April 12, 2004
    Publication date: November 20, 2008
    Applicant: BIOCON LIMITED
    Inventors: Madhav Kulkarni, Surekha K. Prabhu, M.C. Shivakumar, Prijyajit Sengupta, Sanjay Tiwari, Rakesh Mendhe, Nitin Patil, Laxmi Adhikary, Anand Khedkar, Ramakrishnan Melarkode, Ramavana Gururaja, Shrikumar Suryanarayan
  • Process for the purification of macrolides
    Publication number: 20070173642
    Abstract: Process for the recovery of a macrolide in substantially pure form comprising: a) treatment of an impure or crude macrolide with water immiscible solvent, b) optional concentration of the mixture, c) treatment with ammonia gas to phase out impurities, d) separation of impurities, d) optional concentration of the phase containing the macrolide, f) loading on silica gel chromatography, optionally reversed phase or pretreated with silver, and elution of the macrolide, g) affording the macrolide in substantially pure form, h) optional repetition of step f) and g) to afford the macrolide in substantially pure form. The macrolide is preferably tacrolimus, immunomycin or sirolimus.
    Type: Application
    Filed: December 5, 2003
    Publication date: July 26, 2007
    Applicant: BIOCON LIMITED
    Inventors: Nitin Patil, Rakesh Mendhe, Anand Khedkar, Ramakrishnan Melarkode, Ramavana Gururaja