Patents by Inventor Rakhi Saikia

Rakhi Saikia has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • XYLANASE VARIANTS AND POLYNUCLEOTIDES ENCODING SAME
    Publication number: 20230017381
    Abstract: The present invention relates to xylanase variants of a parent xylanase having increased thermostability when compared to the parent xylanase. The present invention also relates to polynucleotides encoding the variants, nucleic acid constructs, vectors, and host cells comprising the polynucleotides, and method of producing the variants of the present invention.
    Type: Application
    Filed: December 17, 2020
    Publication date: January 19, 2023
    Applicant: Novozymes A/S
    Inventors: Rakhi Saikia, Amol Vaijanathappa Shivange, Sohel Dalal, Kenneth Jensen, Lars Olsen, Kristian Bertel Romer M. Krogh, Madelyn Mallison Shoup, Bernardo Vidal, Jr.
  • Mannanase variants and polynucleotides encoding same
    Patent number: 11535837
    Abstract: The present invention relates to mannanase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Grant
    Filed: March 27, 2019
    Date of Patent: December 27, 2022
    Assignee: Novozymes A/S
    Inventors: Rakhi Saikia, Naveen Shivanand Raikar, Padmavathi Balumuri, Jens Erik Nielsen
  • Mannanase variants and polynucleotides encoding same
    Patent number: 11492605
    Abstract: The present invention relates to mannanase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Grant
    Filed: April 26, 2018
    Date of Patent: November 8, 2022
    Assignee: Novozymes A/S
    Inventors: Vivek Srivastava, Markus Klinger, Rakhi Saikia, Vijaya Shankar Nataraj, Sohel Dalal, Jens Erik Nielsen, Rajendra Kulothungan Sainathan
  • Methods for producing lipases
    Patent number: 11371029
    Abstract: The invention relates to a method for generating a preparation of lipase with increased lipolytic activity comprising a step of altering one or more nucleotides in a polynucleotide comprising a first polynucleotide encoding a propeptide operationally linked to a second polynucleotide encoding a lipase, wherein the alteration of one or more nucleotides are made in the first polynucleotide and the alteration independently results in a substitution, an insertion or a deletion in the encoded propeptide amino acid sequence.
    Type: Grant
    Filed: May 4, 2020
    Date of Patent: June 28, 2022
    Assignee: Novozymes A/S
    Inventors: Allan Svendsen, Rakhi Saikia, Sohel Dalal, Vikram Kjoeller Bhatia, Lone Baunsgaard
  • Alpha-amylase variants and polynucleotides encoding same
    Patent number: 11326153
    Abstract: The present invention relates to alpha-amylase variants comprising a substitution at a position corresponding to position 188 and at least one further substitution at a position corresponding to position 242 or 279 or 275 of SEQ ID NO: 1, in particular one or more combinations of substitutions selected from the group consisting of E188P+S242Y, E188P+S242F, E188P+S242H, E188P+S242W, E188P+S242P, E188P+S242I, E188P+S242T, E188P+S242L, E188P+K279W, E188P+K279Y, E188P+K279F, E188P+K279H, E188P+K279I, E188P+K279L, E188P+K279D, E188P+K279M, E188P+K279S, E188P+K279T E188P+K279N, E188P+K279Q, E188P+K279V, E188P+K279A, E188P+N275F, E188P+N275Y, E188P+N275W, and E188P+N275H, wherein the variant has at least 60%, at least 65%, at least 70%, at least 75%, at least 80%, at least 85%, at least 90%, at least 95%, at least 96%, at least 97%, at least 98%, or at least 99%, but less than 100% sequence identity to a parent alpha amylase selected from the group consisting of: SEQ ID NO: 1, SEQ ID NO: 2, SEQ ID NO: 3, SEQ ID NO:
    Type: Grant
    Filed: December 7, 2018
    Date of Patent: May 10, 2022
    Assignee: NOVOZYMES A/S
    Inventors: Carsten Andersen, Vasudeva Prahlada Rao, Rakhi Saikia, Vivek Srivastava, Kendra Darlene Stallings
  • ALPHA-AMYLASE VARIANTS AND POLYNUCLEOTIDES ENCODING SAME
    Publication number: 20210189364
    Abstract: The present invention relates to alpha-amylase variants comprising a substitution at a position corresponding to position 188 and at least one further substitution at a position corresponding to position 242 or 279 or 275 of SEQ ID NO: 1, in particular one or more combinations of substitutions selected from the group consisting of E188P+S242Y, E188P+S242F, E188P+S242H, E188P+S242W, E188P+S242P, E188P+S242I, E188P+S242T, E188P+S242L, E188P+K279W, E188P+K279Y, E188P+K279F, E188P+K279H, E188P+K279I, E188P+K279L, E188P+K279D, E188P+K279M, E188P+K279S, E188P+K279T E188P+K279N, E188P+K279Q, E188P+K279V, E188P+K279A, E188P+N275F, E188P+N275Y, E188P+N275W, and E188P+N275H, wherein the variant has at least 60%, at least 65%, at least 70%, at least 75%, at least 80%, at least 85%, at least 90%, at least 95%, at least 96%, at least 97%, at least 98%, or at least 99%, but less than 100% sequence identity to a parent alpha amylase selected from the group consisting of: SEQ ID NO: 1, SEQ ID NO: 2, SEQ ID NO: 3, SEQ ID NO:
    Type: Application
    Filed: December 7, 2018
    Publication date: June 24, 2021
    Applicant: NOVOZYMES A/S
    Inventors: Carsten Andersen, Vasudeva Prahlada Rao, Rakhi Saikia, Vivek Srivastava, Kendra Darlene Stallings
  • Mannanase Variants and Polynucleotides Encoding Same
    Publication number: 20210130801
    Abstract: The present invention relates to mannanase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Application
    Filed: April 26, 2018
    Publication date: May 6, 2021
    Applicant: Novozymes A/S
    Inventors: Vivek Srivastava, Markus Klinger, Rakhi Saikia, Vijaya Shankar Nataraj, Sohel Dalal, Jens Erik Nielsen, Rajendra Kulothungan Sainathan
  • LIPASE VARIANTS AND POLYNUCLEOTIDES ENCODING SAME
    Publication number: 20210130798
    Abstract: The present invention relates to a lipase variant of a parent lipase, which variant has lipase activity, at least 75% but less than 100% sequence identity to SEQ ID NO: 3 and comprises a substitution at one or more positions corresponding to positions 1; 2; 3; 4; 5; 6; 7; 9; 10; 11; 12; 16; 19; 30; 31; 34; 36; 37; 39; 40; 42; 44; 51; 52; 53; 54; 56; 58; 59; 70; 71; 72; 73; 83; 84; 86; 88; 90; 92; 93; 95; 96; 100; 101; 102; 104; 106; 109; 110; 112; 117; 119; 124; 125; 127; 128; 131; 132; 133; 134; 135; 137; 158; 159; 160; 161; 162; 163; 165; 166; 167; 168; 170; 181; 182; 183; 189; 190; 192; 194; 196; 202; 210; 211; 212; 220; 225; 227; 228; 229; 230; 231; 233; 237; 238; 239; 240; 242; 246; 247; 248; 252; 259; 262; 264; 269 of SEQ ID NO: 3. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Application
    Filed: January 12, 2021
    Publication date: May 6, 2021
    Applicant: Novozymes A/S
    Inventors: Padmavathi Balumuri, Rakhi Saikia, Allan Svendsen, Lone Baunsgaard
  • Mannanase Variants and Polynucleotides Encoding Same
    Publication number: 20210130743
    Abstract: The present invention relates to mannanase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Application
    Filed: April 26, 2018
    Publication date: May 6, 2021
    Applicant: Novozymes A/S
    Inventors: Vivek Srivastava, Markus Klinger, Rakhi Saikia, Vijaya Shankar Nataraj, Sohel Dalal, Jens Erik Nielsen
  • Lipase variants and polynucleotides encoding same
    Patent number: 10920205
    Abstract: The present invention relates to a lipase variant of a parent lipase, which variant has lipase activity, at least 75% but less than 100% sequence identity to SEQ ID NO: 3 and comprises a substitution at one or more positions corresponding to positions 1; 2; 3; 4; 5; 6; 7; 9; 10; 11; 12; 16; 19; 30; 31; 34; 36; 37; 39; 40; 42; 44; 51; 52; 53; 54; 56; 58; 59; 70; 71; 72; 73; 83; 84; 86; 88; 90; 92; 93; 95; 96; 100; 101; 102; 104; 106; 109; 110; 112; 117; 119; 124; 125; 127; 128; 131; 132; 133; 134; 135; 137; 158; 159; 160; 161; 162; 163; 165; 166; 167; 168; 170; 181; 182; 183; 189; 190; 192; 194; 196; 202; 210; 211; 212; 220; 225; 227; 228; 229; 230; 231; 233; 237; 238; 239; 240; 242; 246; 247; 248; 252; 259; 262; 264; 269 of SEQ ID NO: 3. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Grant
    Filed: June 13, 2019
    Date of Patent: February 16, 2021
    Assignee: NOVOZYMES A/S
    Inventors: Padmavathi Balumuri, Rakhi Saikia, Allan Svendsen, Lone Baunsgaard
  • Mannanase Variants and Polynucleotides Encoding Same
    Publication number: 20210024910
    Abstract: The present invention relates to mannanase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Application
    Filed: March 27, 2019
    Publication date: January 28, 2021
    Applicant: Novozymes A/S
    Inventors: Rakhi Saikia, Naveen Shivanand Raikar, Padmavathi Balumuri, Jens Erik Nielsen
  • Methods for producing lipases
    Patent number: 10870838
    Abstract: The present invention relates to a method for generating a preparation of a lipase variant of a parent lipase comprising a step of altering one or more nucleotides in a polynucleotide encoding the parent lipase, wherein the alteration provides at least one disulfide bond and a hydrolytic activity of said lipase variant which is reduced as compared with the hydrolytic activity of the parent lipase. The invention also relates to a polynucleotide encoding the lipase variant, the lipase variant and its use.
    Type: Grant
    Filed: November 30, 2016
    Date of Patent: December 22, 2020
    Assignee: NOVOZYMES A/S
    Inventors: Lone Baunsgaard, Allan Svendsen, Kim Borch, Rakhi Saikia, Jakob Skjold-Jørgensen
  • Lipase variants and polynucleotides encoding same
    Patent number: 10822598
    Abstract: The present invention relates to a lipase variant of a parent lipase, which variant has lipase activity, at least 75% but less than 100% sequence identity to SEQ ID NO: 3 and comprises a substitution at one or more positions corresponding to positions 1; 2; 3; 4; 5; 6; 7; 9; 10; 11; 12; 13; 14; 15; 17; 18; 29; 30; 33; 34; 36; 37; 38; 40; 41; 43; 44; 45; 46; 47; 49; 50; 5 51; 52; 54; 55; 57; 58; 59; 60; 69; 70; 71; 72; 81; 82; 85; 86; 87; 89; 90; 91; 92; 94; 95; 96; 97; 99; 100; 101; 102; 103; 105; 108; 111; 115; 116; 118; 119; 120; 122; 123; 124; 126; 127; 128; 129; 130; 131; 132; 133; 134; 136; 144; 152; 155; 157; 158; 159; 161; 162; 163; 177; 178; 181; 182; 184; 185; 187; 189; 191; 196; 197; 199; 203; 205; 206; 207; 208; 209; 211; 215; 220; 221; 222; 223; 224; 226; 229; 230; 232; 235; 236; 240; 242; 243; 244; 247; 248; 252; 254; 255; 257; 10 260; 261; 262 of SEQ ID NO: 3.
    Type: Grant
    Filed: July 6, 2016
    Date of Patent: November 3, 2020
    Assignee: NOVOZYMES A/S
    Inventors: Rakhi Saikia, Geetha Hiremath Mendez, Sohel Dalal, Padmavathi Balmuri, Santhosh Vasu Mepadam, Lone Baunsgaard, Jesper Vind, Garry Paul Gippert, Kim Borch
  • Methods for Producing Lipases
    Publication number: 20200255812
    Abstract: The invention relates to a method for generating a preparation of lipase with increased lipolytic activity comprising a step of altering one or more nucleotides in a polynucleotide comprising a first polynucleotide encoding a propeptide operationally linked to a second polynucleotide encoding a lipase, wherein the alteration of one or more nucleotides are made in the first polynucleotide and the alteration independently results in a substitution, an insertion or a deletion in the encoded propeptide amino acid sequence
    Type: Application
    Filed: May 4, 2020
    Publication date: August 13, 2020
    Applicant: Novozymes A/S
    Inventors: Allan Svendsen, Rakhi Saikia, Sohel Dalal, Vikram Kjoeller Bhatia, Lone Baunsgaard
  • Lipase variants and polynucleotides encoding same
    Patent number: 10724019
    Abstract: The present invention relates to a lipase variant of a parent lipase, which variant has lipase activity, at least 75% but less than 100% sequence identity to SEQ ID NO: 3 and comprises a substitution at one or more positions corresponding to positions 1; 2; 3; 4; 5; 6; 7; 9; 10; 11; 12; 13; 14; 15; 17; 18; 29; 30; 33; 34; 36; 37; 38; 40; 41; 43; 44; 45; 46; 47; 49; 50; 51; 52; 54; 55; 57; 58; 59; 60; 69; 70; 71; 72; 81; 82; 85; 86; 87; 89; 90; 91; 92; 94; 95; 96; 97; 99; 100; 101; 102; 103; 105; 108; 111; 115; 116; 118; 119; 120; 122; 123; 124; 126; 127; 128; 129; 130; 131; 132; 133; 134; 136; 144; 152; 155; 157; 158; 159; 161; 162; 163; 177; 178; 181; 182; 184; 185; 187; 189; 191; 196; 197; 199; 203; 205; 206; 207; 208; 209; 211; 215; 220; 221; 222; 223; 224; 226; 229; 230; 232; 235; 236; 240; 242; 243; 244; 247; 248; 252; 254; 255; 257; 260; 261; 262 of SEQ ID NO: 3.
    Type: Grant
    Filed: August 14, 2019
    Date of Patent: July 28, 2020
    Assignee: NOVOZYMES A/S
    Inventors: Rakhi Saikia, Geetha Hiremath Mendez, Sohel Dalal, Padmavathi Balumuri, Santhosh Vasu Mepadam, Lone Baunsgaard, Jesper Vind, Garry Paul Gippert, Kim Borch
  • Methods for producing lipases
    Patent number: 10683489
    Abstract: The invention relates to a method for generating a preparation of lipase with increased lipolytic activity comprising a step of altering one or more nucleotides in a polynucleotide comprising a first polynucleotide encoding a propeptide operationally linked to a second polynucleotide encoding a lipase, wherein the alteration of one or more nucleotides are made in the first polynucleotide and the alteration independently results in a substitution, an insertion or a deletion in the encoded propeptide amino acid sequence.
    Type: Grant
    Filed: May 26, 2015
    Date of Patent: June 16, 2020
    Assignee: Novozymes A/S
    Inventors: Allan Svendsen, Rakhi Saikia, Sohel Dalal, Vikram Kjoeller Bhatia, Lone Baunsgaard
  • LIPASE VARIANTS AND POLYNUCLEOTIDES ENCODING SAME
    Publication number: 20190390182
    Abstract: The present invention relates to a lipase variant of a parent lipase, which variant has lipase activity, at least 75% but less than 100% sequence identity to SEQ ID NO: 3 and comprises a substitution at one or more positions corresponding to positions 1; 2; 3; 4; 5; 6; 7; 9; 10; 11; 12; 13; 14; 15; 17; 18; 29; 30; 33; 34; 36; 37; 38; 40; 41; 43; 44; 45; 46; 47; 49; 50; 51; 52; 54; 55; 57; 58; 59; 60; 69; 70; 71; 72; 81; 82; 85; 86; 87; 89; 90; 91; 92; 94; 95; 96; 97; 99; 100; 101; 102; 103; 105; 108; 111; 115; 116; 118; 119; 120; 122; 123; 124; 126; 127; 128; 129; 130; 131; 132; 133; 134; 136; 144; 152; 155; 157; 158; 159; 161; 162; 163; 177; 178; 181; 182; 184; 185; 187; 189; 191; 196; 197; 199; 203; 205; 206; 207; 208; 209; 211; 215; 220; 221; 222; 223; 224; 226; 229; 230; 232; 235; 236; 240; 242; 243; 244; 247; 248; 252; 254; 255; 257; 260; 261; 262 of SEQ ID NO: 3.
    Type: Application
    Filed: August 14, 2019
    Publication date: December 26, 2019
    Applicant: NOVOZYMES A/S
    Inventors: Rakhi Saikia, Geetha Hiremath Mendez, Sohel Dalal, Padmavathi Balumuri, Santhosh Vasu Mepadam, Lone Baunsgaard, Jesper Vind, Garry Paul Gippert, Kim Borch
  • Lipase Variants and Polynucleotides Encoding Same
    Publication number: 20190338260
    Abstract: The present invention relates to a lipase variant of a parent lipase, which variant has lipase activity, at least 75% but less than 100% sequence identity to SEQ ID NO: 3 and comprises a substitution at one or more positions corresponding to positions 1; 2; 3; 4; 5; 6; 7; 9; 10; 11; 12; 16; 19; 30; 31; 34; 36; 37; 39; 40; 42; 44; 51; 52; 53; 54; 56; 58; 59; 70; 71; 72; 73; 83; 84; 86; 88; 90; 92; 93; 95; 96; 100; 101; 102; 104; 106; 109; 110; 112; 117; 119; 124; 125; 127; 128; 131; 132; 133; 134; 135; 137; 158; 159; 160; 161; 162; 163; 165; 166; 167; 168; 170; 181; 182; 183; 189; 190; 192; 194; 196; 202; 210; 211; 212; 220; 225; 227; 228; 229; 230; 231; 233; 237; 238; 239; 240; 242; 246; 247; 248; 252; 259; 262; 264; 269 of SEQ ID NO: 3. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Application
    Filed: June 13, 2019
    Publication date: November 7, 2019
    Applicant: NOVOZYMES A/S
    Inventors: Padmavathi Balumuri, Rakhi Saikia, Allan Svendsen, Lone Baunsgaard
  • Lipase variants and polynucleotides encoding same
    Patent number: 10358635
    Abstract: The present invention relates to a lipase variant of a parent lipase, which variant has lipase activity, at least 75% but less than 100% sequence identity to SEQ ID NO: 3 and comprises a substitution at one or more positions corresponding to positions 1; 2; 3; 4; 5; 6; 7; 9; 10; 11; 12; 16; 19; 30; 31; 34; 36; 37; 39; 40; 42; 44; 51; 52; 53; 54; 56; 58; 59; 70; 71; 72; 73; 83; 84; 86; 88; 90; 92; 93; 95; 96; 100; 101; 102; 104; 106; 109; 110; 112; 117; 119; 124; 125; 127; 128; 131; 132; 133; 134; 135; 137; 158; 159; 160; 161; 162; 163; 165; 166; 167; 168; 170; 181; 182; 183; 189; 190; 192; 194; 196; 202; 210; 211; 212; 220; 225; 227; 228; 229; 230; 231; 233; 237; 238; 239; 240; 242; 246; 247; 248; 252; 259; 262; 264; 269 of SEQ ID NO: 3. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Grant
    Filed: June 20, 2018
    Date of Patent: July 23, 2019
    Assignee: NOVOZYMES A/S
    Inventors: Padmavathi Balumuri, Rakhi Saikia, Allan Svendsen, Lone Baunsgaard
  • LIPASE VARIANTS AND POLYNUCLEOTIDES ENCODING SAME
    Publication number: 20180371438
    Abstract: The present invention relates to a lipase variant of a parent lipase, which variant has lipase activity, at least 75% but less than 100% sequence identity to SEQ ID NO: 3 and comprises a substitution at one or more positions corresponding to positions 1; 2; 3; 4; 5; 6; 7; 9; 10; 11; 12; 13; 14; 15; 17; 18; 29; 30; 33; 34; 36; 37; 38; 40; 41; 43; 44; 45; 46; 47; 49; 50; 5 51; 52; 54; 55; 57; 58; 59; 60; 69; 70; 71; 72; 81; 82; 85; 86; 87; 89; 90; 91; 92; 94; 95; 96; 97; 99; 100; 101; 102; 103; 105; 108; 111; 115; 116; 118; 119; 120; 122; 123; 124; 126; 127; 128; 129; 130; 131; 132; 133; 134; 136; 144; 152; 155; 157; 158; 159; 161; 162; 163; 177; 178; 181; 182; 184; 185; 187; 189; 191; 196; 197; 199; 203; 205; 206; 207; 208; 209; 211; 215; 220; 221; 222; 223; 224; 226; 229; 230; 232; 235; 236; 240; 242; 243; 244; 247; 248; 252; 254; 255; 257; 10 260; 261; 262 of SEQ ID NO: 3.
    Type: Application
    Filed: July 6, 2016
    Publication date: December 27, 2018
    Applicant: NOVOZYMES A/S
    Inventors: Rakhi Saikia, Geetha Hiremath Mendez, Sohel Dalal, Padmavathi Balmuri, Santhosh Vasu Mepadam, Lone Baunsgaard, Jesper Vind, Garry Paul Gippert, Kim Borch