Patents by Inventor Raksha Acharya

Raksha Acharya has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Geminal substituted aminobenzisoxazole compounds as agonists of ?7-nicotinic acetylcholine receptors
    Patent number: 10428062
    Abstract: The present invention relates to novel geminal substituted aminobenzisoxazole compounds, and pharmaceutical compositions of the same, that are suitable as agonists or partial agonists of ?7-nAChR, and methods of preparing these compounds and compositions, and the use of these compounds and compositions in methods of maintaining, treating and/or improving cognitive function. In particular, methods of administering the compound or composition to a patient in need thereof, for example a patient with a cognitive deficiency and/or a desire to enhance cognitive function, that may derive a benefit therefrom.
    Type: Grant
    Filed: August 10, 2016
    Date of Patent: October 1, 2019
    Assignee: Axovant Sciences GmbH
    Inventors: Raksha Acharya, Duane A. Burnett, Matthew Gregory Bursavich, Andrew Simon Cook, Bryce Alden Harrison, Andrew J. McRiner
  • Aminobenzisoxazole compounds as agonists of ?7-nicotinic acetylcholine receptors
    Patent number: 10370370
    Abstract: The present invention relates to novel aminobenzisoxazole compounds, and pharmaceutical compositions of the same, that are suitable as agonists or partial agonists of Alpha7-nAChR, and methods of preparing these compounds and compositions, and the use of these compounds and compositions in methods of maintaining, treating and/or improving cognitive function. In particular, methods of administering the compound or composition to a patient in need thereof, for example a patient with a cognitive deficiency and/or a desire to enhance cognitive function, that may derive a benefit therefrom.
    Type: Grant
    Filed: June 9, 2016
    Date of Patent: August 6, 2019
    Assignee: Axovant Sciences GmbH
    Inventors: Raksha Acharya, Duane A. Burnett, Matthew Gregory Bursavich, Andrew Simon Cook, Bryce Alden Harrison, Andrew J. McRiner
  • Geminal substituted quinuclidine amide compounds as agonists of ?-7 nicotonic acetylcholine receptors
    Patent number: 10183938
    Abstract: The present invention relates to novel geminal substituted quinuclidine amide compounds, and pharmaceutical compositions of the same, that are suitable as agonists or partial agonists of ?7-nAChR, and methods of preparing these compounds and compositions, and the use of these compounds and compositions in methods of maintaining, treating and/or improving cognitive function. In particular, methods of administering the compound or composition to a patient in need thereof, for example a patient with a cognitive deficiency and/or a desire to enhance cognitive function, that may derive a benefit therefrom.
    Type: Grant
    Filed: December 14, 2015
    Date of Patent: January 22, 2019
    Assignee: Axovant Sciences GmbH
    Inventors: Raksha Acharya, Duane A. Burnett, Matthew Gregory Bursavich, Andrew Simon Cook, Bryce Alden Harrison, Gerhard Koenig, Andrew J. Mcriner
  • Aminobenzisoxazole Compounds as Agonists of Alpha7-Nicotinic Acetylcholine Receptors
    Publication number: 20180134696
    Abstract: The present invention relates to novel aminobenzisoxazole compounds, and pharmaceutical compositions of the same, that are suitable as agonists or partial agonists of Alpha7-nAChR, and methods of preparing these compounds and compositions, and the use of these compounds and compositions in methods of maintaining, treating and/or improving cognitive function. In particular, methods of administering the compound or composition to a patient in need thereof, for example a patient with a cognitive deficiency and/or a desire to enhance cognitive function, that may derive a benefit therefrom.
    Type: Application
    Filed: June 9, 2016
    Publication date: May 17, 2018
    Inventors: Raksha Acharya, Duane A. Burnett, Matthew Gregory Bursavich, Andrew Simon Cook, Bryce Alden Harrison, Andrew J. McRiner
  • GEMINAL SUBSTITUTED QUINUCLIDINE AMIDE COMPOUNDS AS AGONISTS OF ALPHA-7 NICOTONIC ACETYLCHOLINE RECEPTORS
    Publication number: 20170369486
    Abstract: The present invention relates to novel geminal substituted quinuclidine amide compounds, and pharmaceutical compositions of the same, that are suitable as agonists or partial agonists of ?7-nAChR, and methods of preparing these compounds and compositions, and the use of these compounds and compositions in methods of maintaining, treating and/or improving cognitive function. In particular, methods of administering the compound or composition to a patient in need thereof, for example a patient with a cognitive deficiency and/or a desire to enhance cognitive function, that may derive a benefit therefrom.
    Type: Application
    Filed: December 14, 2015
    Publication date: December 28, 2017
    Applicant: AXOVANT SCIENCES GMBH
    Inventors: Raksha ACHARYA, Duane A. BURNETT, Matthew Gregory BURSAVICH, Andrew Simon COOK, Bryce Alden HARRISON, Gerhard KOENIG, Andrew J. MCRINER
  • Oxadiazine compounds and methods of use thereof
    Patent number: 9802927
    Abstract: The present disclosure relates to oxadiazine compounds, pharmaceutical compositions comprising an effective amount of an oxadiazine compound and methods for using an oxadiazine compound in the treatment of a neurodegenerative disease, comprising administering to a subject in need thereof an effective amount of an oxadiazine compound.
    Type: Grant
    Filed: June 10, 2016
    Date of Patent: October 31, 2017
    Assignee: DENALI THERAPEUTICS, INC.
    Inventors: Raksha Acharya, Duane A. Burnett, Matthew Gregory Bursavich, Andrew Simon Cook, Bryce Alden Harrison, Andrew J. McRiner
  • Aminoisoxazoline Compounds as Agonists of Alpha7-Nicotinic Acetylcholine Receptors
    Publication number: 20170247393
    Abstract: The present invention relates to novel aminoisoxazoline compounds, and pharmaceutical compositions of the same, that are suitable as agonists or partial agonists of ?7-nAChR, and methods of preparing these compounds and compositions, and the use of these compounds and compositions in methods of maintaining, treating and/or improving cognitive function. In particular, methods of administering the compound or composition to a patient in need thereof, for example a patient with a cognitive deficiency and/or a desire to enhance cognitive function, that may derive a benefit therefrom.
    Type: Application
    Filed: October 12, 2016
    Publication date: August 31, 2017
    Inventors: Raksha Acharya, Duane A. Burnett, Matthew Gregory Bursavich, Andrew Simon Cook, Bryce Alden Harrison, Andrew J. McRiner
  • OXADIAZINE COMPOUNDS AND METHODS OF USE THEREOF
    Publication number: 20170066753
    Abstract: The present disclosure relates to oxadiazine compounds, pharmaceutical compositions comprising an effective amount of an oxadiazine compound and methods for using an oxadiazine compound in the treatment of a neurodegenerative disease, comprising administering to a subject in need thereof an effective amount of an oxadiazine compound.
    Type: Application
    Filed: June 10, 2016
    Publication date: March 9, 2017
    Inventors: Raksha Acharya, Duane A. Burnett, Matthew Gregory Bursavich, Andrew Simon Cook, Bryce Alden Harrison, Andrew J. McRiner
  • Geminal Substituted Aminobenzisoxazole Compounds as Agonists of Alpha7-Nicotinic Acetylcholine Receptors
    Publication number: 20170044155
    Abstract: The present invention relates to novel geminal substituted aminobenzisoxazole compounds, and pharmaceutical compositions of the same, that are suitable as agonists or partial agonists of ?7-nAChR, and methods of preparing these compounds and compositions, and the use of these compounds and compositions in methods of maintaining, treating and/or improving cognitive function. In particular, methods of administering the compound or composition to a patient in need thereof, for example a patient with a cognitive deficiency and/or a desire to enhance cognitive function, that may derive a benefit therefrom.
    Type: Application
    Filed: August 10, 2016
    Publication date: February 16, 2017
    Inventors: Raksha Acharya, Duane A. Burnett, Matthew Gregory Bursavich, Andrew Simon Cook, Bryce Alden Harrison, Andrew J. McRiner
  • AZAINDOLES AS JANUS KINASE INHIBITORS
    Publication number: 20140303142
    Abstract: The instant invention provides compounds of formula I which are JAK inhibitors, and as such are useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer.
    Type: Application
    Filed: September 28, 2012
    Publication date: October 9, 2014
    Inventors: John W. Butcher, David Witter, Christopher Dinsmore, June Kim, John Hendrix, Raksha Acharya, Sean P. Ahearn, Joon Jung, Alexey Rivkin, Philip Jones
  • Chemical compounds
    Publication number: 20080070866
    Abstract: The invention provides compounds of formula I and formula II, their preparation, and their use as pharmaceutically active immunosuppressive agents for the treatment of autoimmune disorders, organ transplant rejection, disorders associated with an activated immune system, as well as other disorders modulated by lymphopenia or S1P receptors.
    Type: Application
    Filed: August 1, 2007
    Publication date: March 20, 2008
    Applicant: Praecis Pharmaceuticals Incorporated
    Inventors: Hongfeng Deng, Ghotas Evindar, Sylvie Bernier, Gang Yao, Aaron Coffin, Hongfang Yang, Raksha Acharya
  • Methods for identifying compounds of interest using encoded libraries
    Publication number: 20070224607
    Abstract: The present invention provides a method for identifying a compound of interest by screening libraries of molecules which include an encoding oligonucleotide tag.
    Type: Application
    Filed: October 23, 2006
    Publication date: September 27, 2007
    Applicant: Praecis Pharmaceuticals Incorporated
    Inventors: Barry Morgan, Stephen Hale, Christopher Arico-Muendel, Matthew Clark, Richard Wagner, David Israel, Malcolm Gefter, Dennis Benjamin, Nils Hansen, Malcolm Kavarana, Steffen Creaser, George Franklin, Paolo Centrella, Raksha Acharya
  • Methods for synthesis of encoded libraries
    Publication number: 20070042401
    Abstract: The present invention provides a method of synthesizing libraries of molecules which include an encoding oligonucleotide tag.
    Type: Application
    Filed: June 9, 2006
    Publication date: February 22, 2007
    Applicant: Praecis Pharmaceuticals, Inc.
    Inventors: Barry Morgan, Stephen Hale, Christopher Arico-Muendel, Matthew Clark, Richard Wagner, David Israel, Malcolm Gefter, Dennis Benjamin, Nils Hansen, Malcolm Kavarana, Steffen Creaser, George Franklin, Paolo Centrella, Raksha Acharya
  • Methods for synthesis of encoded libraries
    Publication number: 20050158765
    Abstract: The present invention provides a method of synthesizing libraries of molecules which include an encoding oligonucleotide tag.
    Type: Application
    Filed: December 17, 2004
    Publication date: July 21, 2005
    Applicant: Praecis Pharmaceuticals, Inc.
    Inventors: Barry Morgan, Stephen Hale, Christopher Arico-Muendel, Matthew Clark, Richard Wagner, David Israel, Malcolm Gefter, Dennis Benjamin, Nils Hansen, Malcolm Kavarana, Steffen Creaser, George Franklin, Paolo Centrella, Raksha Acharya