Patents by Inventor Ralf A. Lange

Ralf A. Lange has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bioequivalence test for iron-containing formulations
    Patent number: 7169359
    Abstract: A rapid method for assessing the bioequivalence of iron in iron-supplement formulations, particularly iron-sucrose formulations is described, which is based upon the kinetics of reduction of iron (III) to iron (II) in a sample of the formulation. Quality control methods and associated kits also are described.
    Type: Grant
    Filed: November 2, 2004
    Date of Patent: January 30, 2007
    Assignee: Luitpold Pharmaceuticals, Inc.
    Inventors: Mary Jane Helenek, Ralf A. Lange, Richard P. Lawrence
  • Methods and compositions for administration of iron for the treatment of restless leg syndrome
    Patent number: 6960571
    Abstract: A method of treating Restless Leg Syndrome, includes administering to a subject an iron complex having an iron release rate greater than IDI. The iron release rate is determined at a concentration of at least 2,000 ?g/dl.
    Type: Grant
    Filed: March 14, 2003
    Date of Patent: November 1, 2005
    Assignee: Luitpold Pharmaceuticals, Inc.
    Inventors: Mary Jane Helenek, Ralf A. Lange, Fred B. Oldham, Marc L. Tokars
  • Bioequivalence test for iron-containing formulations
    Patent number: 6911342
    Abstract: A rapid method for assessing the bioequivalence of iron in iron-supplement formulations, particularly iron-sucrose formulations is described, which is based upon the kinetics of reduction of iron (III) to iron (II) in a sample of the formulation. Quality control methods and associated kits also are described.
    Type: Grant
    Filed: August 26, 2002
    Date of Patent: June 28, 2005
    Assignee: Luitpold Pharmaceuticals, Inc.
    Inventors: Mary Jane Helenek, Ralf A. Lange, Richard P. Lawrence
  • Methods and compositions for administration of iron for the treatment of restless leg syndrome
    Publication number: 20040180849
    Abstract: A method of treating Restless Leg Syndrome, includes administering to a subject an iron complex having an iron release rate greater than IDI. The iron release rate is determined at a concentration of at least 2,000 &mgr;g/dl.
    Type: Application
    Filed: March 14, 2003
    Publication date: September 16, 2004
    Inventors: Mary Jane Helenek, Ralf A. Lange, Fred B. Oldham, Marc L. Tokars
  • Bioequivalence test for iron-containing formulations
    Publication number: 20040038416
    Abstract: A rapid method for assessing the bioequivalence of iron in iron-supplement formulations, particularly iron-sucrose formulations is described, which is based upon the kinetics of reduction of iron (III) to iron (II) in a sample of the formulation. Quality control methods and associated kits also are described.
    Type: Application
    Filed: August 26, 2002
    Publication date: February 26, 2004
    Applicant: Luitpold Pharmaceuticals, Inc.
    Inventors: Mary Jane Helenek, Ralf A. Lange, Richard P. Lawrence
  • Iron dextran formulations
    Patent number: 5624668
    Abstract: Ferric oxyhydroxide-dextran compositions for treating iron deficiency having ellipsoidal particles with a preferred molecular weight range of about 250,000 to 300,000 daltons.
    Type: Grant
    Filed: September 29, 1995
    Date of Patent: April 29, 1997
    Assignee: Luitpold Pharmaceuticals, Inc.
    Inventors: Richard P. Lawrence, Ralf A. Lange, Chin Wu, Mary J. Helenek