Patents by Inventor Ralf Anderskewitz

Ralf Anderskewitz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR TREATING PULMONARY EMPHYSEMA USING SUBSTITUTED 2-AZA-BICYCLO[2.2.1]HEPTANE-3-CARBOXYLIC ACID (BENZYL-CYANO-METHYL)-AMIDES INHIBITORS OF CATHEPSIN C
    Publication number: 20230310373
    Abstract: This invention relates to 2-Aza-bicyclo[2.2.1]heptane-3-carboxylic acid (benzyl-cyano-methyl)-amides of formula 1 and their use as inhibitors of Cathepsin C, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of diseases connected with dipeptidyl peptidase I activity, e.g. respiratory diseases.
    Type: Application
    Filed: June 8, 2023
    Publication date: October 5, 2023
    Inventors: Ralf ANDERSKEWITZ, Florian BINDER, Matthias GRAUERT, Marc GRUNDL, Peter Wilhelm HAEBEL, Thorsten OOST, Alexander PAUTSCH, Stefan PETERS, Viktor VINTONYAK
  • METHODS FOR TREATING PULMONARY EMPHYSEMA USING SUBSTITUTED 2-AZA-BICYCLO[2.2.1]HEPTANE-3-CARBOXYLIC ACID (BENZYL-CYANO-METHYL)-AMIDES INHIBITORS OF CATHEPSIN C
    Publication number: 20210260027
    Abstract: This invention relates to 2-Aza-bicyclo[2.2.1]heptane-3-carboxylic acid (benzyl-cyano-methyl)-amides of formula 1 and their use as inhibitors of Cathepsin C, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of diseases connected with dipeptidyl peptidase I activity, e.g. respiratory diseases.
    Type: Application
    Filed: April 19, 2021
    Publication date: August 26, 2021
    Inventors: Ralf ANDERSKEWITZ, Florian BINDER, Matthias GRAUERT, Marc GRUNDL, Peter Wilhelm HAEBEL, Thorsten OOST, Alexander PAUTSCH, Stefan PETERS, Viktor VINTONYAK
  • METHODS FOR TREATING PULMONARY EMPHYSEMA USING SUBSTITUTED 2-AZA-BICYCLO[2.2.1]HEPTANE-3-CARBOXYLIC ACID (BENZYL-CYANO-METHYL)-AMIDES INHIBITORS OF CATHEPSIN C
    Publication number: 20200138780
    Abstract: This invention relates to 2-Aza-bicyclo[2.2.1]heptane-3-carboxylic acid (benzyl-cyano-methyl)-amides of formula 1 and their use as inhibitors of Cathepsin C, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of diseases connected with dipeptidyl peptidase I activity, e.g. respiratory diseases.
    Type: Application
    Filed: December 19, 2019
    Publication date: May 7, 2020
    Inventors: Ralf ANDERSKEWITZ, Florian BINDER, Matthias GRAUERT, Marc GRUNDL, Peter Wilhelm HAEBEL, Thorsten OOST, Alexander PAUTSCH, Stefan PETERS, Viktor VINTONYAK
  • METHODS FOR TREATING PULMONARY EMPHYSEMA USING SUBSTITUTED 2-AZA-BICYCLO[2.2.1]HEPTANE-3-CARBOXYLIC ACID (BENZYL-CYANO-METHYL)-AMIDES INHIBITORS OF CATHEPSIN C
    Publication number: 20190167636
    Abstract: This invention relates to 2-Aza-bicyclo[2.2.1]heptane-3-carboxylic acid (benzyl-cyano-methyl)-amides of formula 1 and their use as inhibitors of Cathepsin C, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of diseases connected with dipeptidyl peptidase I activity, e.g. respiratory diseases.
    Type: Application
    Filed: February 8, 2019
    Publication date: June 6, 2019
    Inventors: Ralf ANDERSKEWITZ, Florian BINDER, Matthias GRAUERT, Marc GRUNDL, Peter Wilhelm HAEBEL, Thorsten OOST, Alexander PAUTSCH, Stefan PETERS, Viktor VINTONYAK
  • Methods for treating pulmonary emphysema using substituted 2-Aza-bicyclo[2.2.1]heptane-3-carboxylic acid (benzyl-cyano-methyl)-amides inhibitors of Cathepsin C
    Patent number: 10238633
    Abstract: This invention relates to 2-Aza-bicyclo[2.2.1]heptane-3-carboxylic acid (benzyl-cyano-methyl)-amides of formula 1 and their use as inhibitors of Cathepsin C, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of diseases connected with dipeptidyl peptidase I activity, e.g. respiratory diseases.
    Type: Grant
    Filed: June 6, 2017
    Date of Patent: March 26, 2019
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Ralf Anderskewitz, Florian Binder, Matthias Grauert, Marc Grundl, Peter Wilhelm Haebel, Thorsten Oost, Alexander Pautsch, Stefan Peters, Viktor Vintonyak
  • METHODS FOR TREATING PULMONARY EMPHYSEMA USING SUBSTITUTED 2-AZA-BICYCLO[2.2.1]HEPTANE-3-CARBOXYLIC ACID (BENZYL-CYANO-METHYL)-AMIDES INHIBITORS OF CATHEPSIN C
    Publication number: 20170266160
    Abstract: This invention relates to 2-Aza-bicyclo[2.2.1]heptane-3-carboxylic acid (benzyl-cyano-methyl)-amides of formula 1 and their use as inhibitors of Cathepsin C, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of diseases connected with dipeptidyl peptidase I activity, e.g. respiratory diseases.
    Type: Application
    Filed: June 6, 2017
    Publication date: September 21, 2017
    Inventors: Ralf ANDERSKEWITZ, Florian BINDER, Matthias GRAUERT, Marc GRUNDL, Peter Wilhelm HAEBEL, Thorsten OOST, Alexander PAUTSCH, Stefan PETERS, Viktor VINTONYAK
  • Methods for treating pulmonary emphysema using substituted 2-Aza-bicyclo[2.2.1]heptane-3-carboxylic acid (benzyl-cyano-methyl)-amides inhibitors of cathepsin C
    Patent number: 9713606
    Abstract: This invention relates to 2-Aza-bicyclo[2.2.1]heptane-3-carboxylic acid (benzyl-cyano-methyl)-amides of formula 1 and their use as inhibitors of Cathepsin C, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of diseases connected with dipeptidyl peptidase I activity, e.g. respiratory diseases.
    Type: Grant
    Filed: December 1, 2015
    Date of Patent: July 25, 2017
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Ralf Anderskewitz, Florian Binder, Matthias Grauert, Marc Grundl, Peter Wilhelm Haebel, Thorsten Oost, Alexander Pautsch, Stefan Peters, Viktor Vintonyak
  • Substituted bicyclic dihydropyrimidinones and their use as inhibitors of neutrophil elastase activity
    Patent number: 9657015
    Abstract: Substituted bicyclic dihydropyrimidinones of formula 1 which are inhibitors of neutrophil elastase activity and useful as medicaments for the treatment of, inter alia, COPD.
    Type: Grant
    Filed: July 27, 2015
    Date of Patent: May 23, 2017
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Christian Gnamm, Ralf Anderskewitz, Holger Hoesch, Gerd Morschhaeuser, Thorsten Oost, Stefan Peters, Uwe Joerg Ries
  • Substituted bicyclic dihydropyrimidinones and their use as inhibitors of neutrophil elastase activity
    Patent number: 9475779
    Abstract: Substituted bicyclic dihydropyrimidinones of formula 1 which are inhibitors of neutrophil elastase and useful as medicaments for the treatment of, inter alia, COPD.
    Type: Grant
    Filed: July 27, 2015
    Date of Patent: October 25, 2016
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Thorsten Oost, Ralf Anderskewitz, Christian Gnamm, Holger Hoesch, Gerd Morschhaeuser, Stefan Peters, Uwe Joerg Ries
  • Substituted bicyclic dihydropyrimidinones and their use as inhibitors of neutrophil elastase activity
    Patent number: 9458113
    Abstract: Substituted dihydropyrimidinones of formula 1 which are neutrophil elastase inhibitors and useful as medicaments for the treatment of, inter alia, COPD.
    Type: Grant
    Filed: July 27, 2015
    Date of Patent: October 4, 2016
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Stefan Peters, Ralf Anderskewitz, Christian Gnamm, Holger Hoesch, Gerd Morschhaeuser, Thorsten Oost, Uwe Joerg Ries
  • Substituted oxetanes and their use as inhibitors of cathepsin C
    Patent number: 9440960
    Abstract: This invention relates to a compound of formula I and their use as inhibitors of Cathepsin C, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of diseases connected with dipeptidyl peptidase I activity, e.g. respiratory diseases.
    Type: Grant
    Filed: July 31, 2015
    Date of Patent: September 13, 2016
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Matthias Grauert, Ralf Anderskewitz, Achim Bixenmann, Marc Grundl, Peter Wilhelm Haebel, Alexander Pautsch
  • Substituted bicyclic dihydropyrimidinones and their use as inhibitors of neutrophil elastase activity
    Patent number: 9440930
    Abstract: Substituted bicyclic dihydropyrimidinones of formula 1 and their use as inhibitors of neutrophil elastase activity.
    Type: Grant
    Filed: July 27, 2015
    Date of Patent: September 13, 2016
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Thorsten Oost, Ralf Anderskewitz, Christian Gnamm, Gerd Morschhaeuser, Stefan Peters, Uwe Joerg Ries
  • METHODS FOR TREATING PULMONARY EMPHYSEMA USING SUBSTITUTED 2-AZA-BICYCLO[2.2.1]HEPTANE-3-CARBOXYLIC ACID (BENZYL-CYANO-METHYL)-AMIDES INHIBITORS OF CATHEPSIN C
    Publication number: 20160081982
    Abstract: This invention relates to 2-Aza-bicyclo[2.2.1]heptane-3-carboxylic acid (benzyl-cyano-methyl)-amides of formula 1 and their use as inhibitors of Cathepsin C, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of diseases connected with dipeptidyl peptidase I activity, e.g. respiratory diseases.
    Type: Application
    Filed: December 1, 2015
    Publication date: March 24, 2016
    Inventors: Ralf ANDERSKEWITZ, Florian BINDER, Matthias GRAUERT, Marc GRUNDL, Peter Wilhelm HAEBEL, Thorsten OOST, Alexander PAUTSCH, Stefan PETERS, Viktor VINTONYAK
  • Substituted dihydropyrimidinones and their use as inhibitors of neutrophil elastase activity
    Patent number: 9290457
    Abstract: Substituted dihydropyrimidinones of formula 1 which are inhibitors of neutrophil elastase activity and which are useful as medicaments for the treatment of, inter alia, COPD.
    Type: Grant
    Filed: July 27, 2015
    Date of Patent: March 22, 2016
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Stefan Peters, Ralf Anderskewitz, Gerd Morschhaeuser, Thorsten Oost
  • SUBSTITUTED BICYCLIC DIHYDROPYRIMIDINONES AND THEIR USE AS INHIBITORS OF NEUTROPHIL ELASTASE ACTIVITY
    Publication number: 20160039812
    Abstract: Substituted bicyclic dihydropyrimidinones of formula 1 which are inhibitors of neutrophil elastase activity and useful as medicaments for the treatment of, inter alia, COPD.
    Type: Application
    Filed: July 27, 2015
    Publication date: February 11, 2016
    Inventors: Christian GNAMM, Ralf ANDERSKEWITZ, Holger HOESCH, Gerd MORSCHHAEUSER, Thorsten OOST, Stefan PETERS, Uwe Joerg RIES
  • SUBSTITUTED DIHYDROPYRIMIDINONES AND THEIR USE AS INHIBITORS OF NEUTROPHIL ELASTASE ACTIVITY
    Publication number: 20160031825
    Abstract: Substituted dihydropyrimidinones of formula 1 which are inhibitors of neutrophil elastase activity and which are useful as medicaments for the treatment of, inter alia, COPD.
    Type: Application
    Filed: July 27, 2015
    Publication date: February 4, 2016
    Inventors: Stefan PETERS, Ralf ANDERSKEWITZ, Gerd MORSCHHAEUSER, Thorsten OOST
  • SUBSTITUTED BICYCLIC DIHYDROPYRIMIDINONES AND THEIR USE AS INHIBITORS OF NEUTROPHIL ELASTASE ACTIVITY
    Publication number: 20160031831
    Abstract: Substituted bicyclic dihydropyrimidinones of formula 1 and their use as inhibitors of neutrophil elastase activity.
    Type: Application
    Filed: July 27, 2015
    Publication date: February 4, 2016
    Inventors: Thorsten OOST, Ralf ANDERSKEWITZ, Christian GNAMM, Gerd MORSCHHAEUSER, Stefan PETERS, Uwe Joerg RIES
  • SUBSTITUTED BICYCLIC DIHYDROPYRIMIDINONES AND THEIR USE AS INHIBITORS OF NEUTROPHIL ELASTASE ACTIVITY
    Publication number: 20160031830
    Abstract: Substituted dihydropyrimidinones of formula 1 which are neutrophil elastase inhibitors and useful as medicaments for the treatment of, inter alia, COPD.
    Type: Application
    Filed: July 27, 2015
    Publication date: February 4, 2016
    Inventors: Stefan PETERS, Ralf ANDERSKEWITZ, Christian GNAMM, Holger HOESCH, Gerd MORSCHHAEUSER, Thorsten OOST, Uwe Joerg RIES
  • SUBSTITUTED OXETANES AND THEIR USE AS INHIBITORS OF CATHEPSIN C
    Publication number: 20160031861
    Abstract: This invention relates to a compound of formula I and their use as inhibitors of Cathepsin C, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of diseases connected with dipeptidyl peptidase I activity, e.g. respiratory diseases.
    Type: Application
    Filed: July 31, 2015
    Publication date: February 4, 2016
    Inventors: Matthias GRAUERT, Ralf ANDERSKEWITZ, Achim BIXENMANN, Marc GRUNDL, Peter Wilhelm HAEBEL, Alexander PAUTSCH
  • SUBSTITUTED BICYCLIC DIHYDROPYRIMIDINONES AND THEIR USE AS INHIBITORS OF NEUTROPHIL ELASTASE ACTIVITY
    Publication number: 20160031829
    Abstract: Substituted bicyclic dihydropyrimidinones of formula 1 which are inhibitors of neutrophil elastase and useful as medicaments for the treatment of, inter alia, COPD.
    Type: Application
    Filed: July 27, 2015
    Publication date: February 4, 2016
    Inventors: Thorsten OOST, Ralf ANDERSKEWITZ, Christian GNAMM, Holger HOESCH, Gerd MORSCHHAEUSER, Stefan PETERS, Uwe Joerg RIES