Patents by Inventor Ralf Bickel

Ralf Bickel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210172010
    Abstract: The invention relates to devices and methods for the detection of specific interactions between probe and target molecules. In particular, the invention relates to methods for the qualitative and/or quantitative detection of targets, including: introducing a sample containing targets into a reaction chamber formed between a first surface of the device and a second surface of a device, which is preferably located opposite to the first surface, wherein the distance between the first and the second surface is variable; and detecting the targets.
    Type: Application
    Filed: January 21, 2021
    Publication date: June 10, 2021
    Inventors: Ralf Bickel, Alexandra Dworrak, Thomas Ellinger, Eugen Ermantraut, Torsten Schulz, Thomas Ullrich
  • Patent number: 10399260
    Abstract: A method for producing a composite sealing element, in particular for forming a seal at a retractable pane of a vehicle window, wherein the composite sealing element is produced from at least one extruded element portion and at least one element part formed by injection molding in a mold cavity of a mold, with the element part being molded onto an end face, bounding the mold cavity, of the extruded portion. A change in the dimensions of the composite sealing element as a result of the length of the extruded element portion differing from the nominal value is counteracted by changing the arrangement of the end face of the extruded element portion with respect to the mold cavity.
    Type: Grant
    Filed: December 16, 2015
    Date of Patent: September 3, 2019
    Assignee: CQLT SAARGUMMI TECHNOLOGIES S.À.R.L.
    Inventors: Michael Lorig, Ralf Bickel, Suleyman Samanci
  • Patent number: 10365276
    Abstract: The present invention relates to devices and methods for the qualitative and/or quantitative detection of particles. In particular, the invention relates to devices for the detection of particles, comprising a reaction chamber formed within a chamber body between a first surface and a second surface, wherein the second surface is located opposite to the first surface, and one or more displacers, wherein the distance between the first surface and the second surface is variable via the one or more displacers at least in one or more parts of the surface area of the first surface and/or second surface. The invention also relates to corresponding methods for the detection of particles.
    Type: Grant
    Filed: September 28, 2017
    Date of Patent: July 30, 2019
    Assignee: ALERE TECHNOLOGIES GMBH
    Inventors: Eugen Ermantraut, Ralf Bickel, Torsten Schulz, Thomas Ullrich, Jens Tuchscheerer
  • Publication number: 20180135116
    Abstract: The present invention relates to devices and methods for the detection of analytes. In particular, the invention relates to methods for the qualitative and/or quantitative detection of analytes, comprising a microarray on a substrate, onto which probe molecules are immobilized on array elements, said microarray being disposed on a first surface of the device; and a detection chamber formed between the first surface including the microarray disposed thereon and a second surface, wherein the distance between the microarray and the second surface is variable, and wherein the second surface has a displacement structure.
    Type: Application
    Filed: February 27, 2017
    Publication date: May 17, 2018
    Applicant: CLONDIAG GMBH
    Inventors: Eugen Emantraut, Ralf Bickel, Torsten Schulz, Thomas Ullrich
  • Publication number: 20180088115
    Abstract: The present invention relates to devices and methods for the qualitative and/or quantitative detection of particles. In particular, the invention relates to devices for the detection of particles, comprising a reaction chamber formed within a chamber body between a first surface and a second surface, wherein the second surface is located opposite to the first surface, and one or more displacers, wherein the distance between the first surface and the second surface is variable via the one or more displacers at least in one or more parts of the surface area of the first surface and/or second surface. The invention also relates to corresponding methods for the detection of particles.
    Type: Application
    Filed: September 28, 2017
    Publication date: March 29, 2018
    Applicant: CLONDIAG GMBH
    Inventors: Eugen Ermantraut, Ralf Bickel, Torsten Schulz, Thomas Ullrich, Jens Tuchscheerer
  • Publication number: 20170355113
    Abstract: A method for producing a composite sealing element, in particular for forming a seal at a retractable pane of a vehicle window, wherein the composite sealing element is produced from at least one extruded element portion and at least one element part formed by injection molding in a mold cavity of a mold, with the element part being molded onto an end face, bounding the mold cavity, of the extruded portion. A change in the dimensions of the composite sealing element as a result of the length of the extruded element portion differing from the nominal value is counteracted by changing the arrangement of the end face of the extruded element portion with respect to the mold cavity.
    Type: Application
    Filed: December 16, 2015
    Publication date: December 14, 2017
    Inventors: Michael LORIG, Ralf BICKEL, Suleyman SAMANCI
  • Patent number: 9791441
    Abstract: The present invention relates to devices and methods for the qualitative and/or quantitative detection of particles. In particular, the invention relates to devices for the detection of particles, comprising a reaction chamber formed within a chamber body between a first surface and a second surface, wherein the second surface is located opposite to the first surface, and one or more displacers, wherein the distance between the first surface and the second surface is variable via the one or more displacers at least in one or more parts of the surface area of the first surface and/or second surface. The invention also relates to corresponding methods for the detection of particles.
    Type: Grant
    Filed: June 17, 2013
    Date of Patent: October 17, 2017
    Assignee: CLONDIAG GMBH
    Inventors: Eugen Ermantraut, Ralf Bickel, Torsten Schulz, Thomas Ullrich, Jens Tuchscheerer
  • Patent number: 9580745
    Abstract: The present invention relates to devices and methods for the detection of analytes. In particular, the invention relates to methods for the qualitative and/or quantitative detection of analytes, comprising a microarray on a substrate, onto which probe molecules are immobilized on array elements, said microarray being disposed on a first surface of the device; and a detection chamber formed between the first surface including the microarray disposed thereon and a second surface, wherein the distance between the microarray and the second surface is variable, and wherein the second surface has a displacement structure.
    Type: Grant
    Filed: September 1, 2014
    Date of Patent: February 28, 2017
    Assignee: CLONDIAG GMBH
    Inventors: Eugen Ermantraut, Ralf Bickel, Torsten Schulz, Thomas Ullrich
  • Publication number: 20160237482
    Abstract: The invention relates to devices and methods for the detection of specific interactions between probe and target molecules. In particular, the invention relates to methods for the qualitative and/or quantitative detection of targets, including: introducing a sample containing targets into a reaction chamber formed between a first surface of the device and a second surface of a device, which is preferably located opposite to the first surface, wherein the distance between the first and the second surface is variable; and detecting the targets.
    Type: Application
    Filed: December 22, 2014
    Publication date: August 18, 2016
    Applicant: CLONDIAG GMBH
    Inventors: Ralf Bickel, Alexandra Dworrak, Thomas Ellinger, Eugen Ermantraut, Torsten Schulz, Thomas Ullrich
  • Publication number: 20150284785
    Abstract: The present invention relates to devices and methods for the detection of analytes. In particular, the invention relates to methods for the qualitative and/or quantitative detection of analytes, comprising a microarray on a substrate, onto which probe molecules are immobilized on array elements, said microarray being disposed on a first surface of the device; and a detection chamber formed between the first surface including the microarray disposed thereon and a second surface, wherein the distance between the microarray and the second surface is variable, and wherein the second surface has a displacement structure.
    Type: Application
    Filed: September 1, 2014
    Publication date: October 8, 2015
    Inventors: Eugen Ermantraut, Ralf Bickel, Torsten Schulz, Thomas Ullrich
  • Patent number: 8916348
    Abstract: The invention relates to devices and methods for the detection of specific interactions between probe and target molecules. In particular, the invention relates to methods for the qualitative and/or quantitative detection of targets, including: introducing a sample containing targets into a reaction chamber formed between a first surface of the device and a second surface of a device, which is preferably located opposite to the first surface, wherein the distance between the first and the second surface is variable; and detecting the targets.
    Type: Grant
    Filed: November 6, 2006
    Date of Patent: December 23, 2014
    Assignee: Clondiag GmbH
    Inventors: Ralf Bickel, Alexandra Dworrak, Thomas Ellinger, Eugen Ermantraut, Torsten Schulz, Thomas Ullrich
  • Patent number: 8828741
    Abstract: The present invention relates to devices and methods for the detection of analytes. In particular, the invention relates to methods for the qualitative and/or quantitative detection of analytes, comprising a microarray on a substrate, onto which probe molecules are immobilized on array elements, said microarray being disposed on a first surface of the device; and a detection chamber formed between the first surface including the microarray disposed thereon and a second surface, wherein the distance between the microarray and the second surface is variable, and wherein the second surface has a displacement structure.
    Type: Grant
    Filed: November 6, 2006
    Date of Patent: September 9, 2014
    Assignee: Clondiag GmbH
    Inventors: Eugen Ermantraut, Ralf Bickel, Torsten Schulz, Thomas Ullrich
  • Publication number: 20130295657
    Abstract: The present invention relates to devices and methods for the qualitative and/or quantitative detection of particles. In particular, the invention relates to devices for the detection of particles, comprising a reaction chamber formed within a chamber body between a first surface and a second surface, wherein the second surface is located opposite to the first surface, and one or more displacers, wherein the distance between the first surface and the second surface is variable via the one or more displacers at least in one or more parts of the surface area of the first surface and/or second surface. The invention also relates to corresponding methods for the detection of particles.
    Type: Application
    Filed: June 17, 2013
    Publication date: November 7, 2013
    Inventors: Eugen Ermantraut, Ralf Bickel, Torsten Schulz, Thomas Ullrich, Jens Tuchscheerer
  • Patent number: 8467039
    Abstract: The present invention relates to devices and methods for the qualitative and/or quantitative detection of particles. In particular, the invention relates to devices for the detection of particles, comprising a reaction chamber formed within a chamber body between a first surface and a second surface, wherein the second surface is located opposite to the first surface, and one or more displacers, wherein the distance between the first surface and the second surface is variable via the one or more displacers at least in one or more parts of the surface area of the first surface and/or second surface. The invention also relates to corresponding methods for the detection of particles.
    Type: Grant
    Filed: October 14, 2011
    Date of Patent: June 18, 2013
    Assignee: Clondiag GmbH
    Inventors: Eugen Ermantraut, Ralf Bickel, Torsten Schulz, Thomas Ullrich, Jens Tuchscheerer
  • Publication number: 20120088252
    Abstract: The present invention relates to devices and methods for the qualitative and/or quantitative detection of particles. In particular, the invention relates to devices for the detection of particles, comprising a reaction chamber formed within a chamber body between a first surface and a second surface, wherein the second surface is located opposite to the first surface, and one or more displacers, wherein the distance between the first surface and the second surface is variable via the one or more displacers at least in one or more parts of the surface area of the first surface and/or second surface. The invention also relates to corresponding methods for the detection of particles.
    Type: Application
    Filed: October 14, 2011
    Publication date: April 12, 2012
    Applicant: ALERE TECHNOLOGIES GmbH
    Inventors: Eugen Ermantraut, Ralf Bickel, Torsten Schulz, Thomas Ullrich, Jens Tuchscheerer
  • Patent number: 8040494
    Abstract: The present invention relates to devices and methods for the qualitative and/or quantitative detection of particles. In particular, the invention relates to devices for the detection of particles, comprising a reaction chamber formed within a chamber body between a first surface and a second surface, wherein the second surface is located opposite to the first surface, and one or more displacers, wherein the distance between the first surface and the second surface is variable via the one or more displacers at least in one or more parts of the surface area of the first surface and/or the second surface.
    Type: Grant
    Filed: November 6, 2006
    Date of Patent: October 18, 2011
    Assignee: Clondiag GmbH
    Inventors: Eugen Ermantraut, Ralf Bickel, Torsten Schulz, Thomas Ullrich, Jens Tuchscheerer
  • Publication number: 20090082219
    Abstract: The present invention relates to devices and methods for the detection of analytes. In particular, the invention relates to methods for the qualitative and/or quantitative detection of analytes, comprising a microarray on a substrate, onto which probe molecules are immobilized on array elements, said microarray being disposed on a first surface of the device; and a detection chamber formed between the first surface including the microarray disposed thereon and a second surface, wherein the distance between the microarray and the second surface is variable, and wherein the second surface has a displacement structure.
    Type: Application
    Filed: November 6, 2006
    Publication date: March 26, 2009
    Applicant: CLONDIAG GMBH
    Inventors: Eugen Ermantraut, Ralf Bickel, Torsten Schulz, Thomas Ullrich
  • Publication number: 20090079963
    Abstract: The present invention relates to devices and methods for the qualitative and/or quantitative detection of particles. In particular, the invention relates to devices for the detection of particles, comprising a reaction chamber formed within a chamber body between a first surface and a second surface, wherein the second surface is located opposite to the first surface, and one or more displacers, wherein the distance between the first surface and the second surface is variable via the one or more displacers at least in one or more parts of the surface area of the first surface and/or the second surface.
    Type: Application
    Filed: November 6, 2006
    Publication date: March 26, 2009
    Applicant: CLONDIAG GMBH
    Inventors: Eugen Ermantraut, Ralf Bickel, Torsten Schulz, Thomas Ullrich, Jens Tuchscheerer
  • Publication number: 20070254372
    Abstract: The invention relates to devices and methods for the detection of specific interactions between probe and target molecules. In particular, the invention relates to methods for the qualitative and/or quantitative detection of targets, including: introducing a sample containing targets into a reaction chamber formed between a first surface of the device and a second surface of a device, which is preferably located opposite to the first surface, wherein the distance between the first and the second surface is variable; and detecting the targets.
    Type: Application
    Filed: November 6, 2006
    Publication date: November 1, 2007
    Inventors: Ralf Bickel, Alexandra Dworrak, Thomas Ellinger, Eugen Ermantraut, Torsten Schulz, Thomas Ullrich
  • Publication number: 20060201622
    Abstract: Methods, devices and support profiles are configured to match the method and device in profiles used to attach a support section for rubber seals to automobile body parts in the shortest possible time with the minimum of tools and personnel. The methods and devices are adaptable in such a way that modifications to the geometry of the sealing section and to the contours of the body parts are accommodated without long stoppages of the assembly line. The support sections and connecting regions mold to all the contours of automobile bodyworks, in particular corner regions, and permit the attachment of various sealing regions and application of extreme detachment forces. The support section for the sealing section is attached to the support surface in one single operation. The sub-steps of said operation are carried out by an industrial robot. Adhesive is applied to the support section during its production.
    Type: Application
    Filed: March 26, 2002
    Publication date: September 14, 2006
    Inventors: Ralf Sehr, Ralf Bickel