Abstract: A laser therapy device comprising a pulsed laser light source. Each triggering of tissue irradiation causes application of a first heating laser pulse of a first power and a first pulse duration and at least a second heating laser pulse of a second power and a second pulse duration to the tissue. Changes in volume resulting from the rising and the decreasing power gradient of the first laser pulse are detected. The therapy device, on the basis of the measured values relative to the change in volume and taking into consideration at least the predetermined rises of the power gradients of the first heating laser pulse, determines an estimated value for the temperature increase in the tissue during irradiation of the first heating laser pulse, and generates, from the estimated value, a command that causes adjustment of the second power and/or the second pulse duration of the second laser pulse.

Abstract: A medical device may include an ablation device configured to deliver ablation energy to a treatment site. The medical device may further include a probe device configured to deliver excitation radiation to the treatment site. Further the medical device may include a radiation-receiving device configured to receive photoluminescence radiation emitted from the treatment site in response to the treatment site being illuminated by the excitation radiation and to generate a detection signal in response to the received photoluminescence radiation. Additionally, the excitation radiation may be different from the ablation energy.

Abstract: A medical device may include an ablation device configured to deliver ablation energy to a treatment site. The medical device may further include a probe device configured to deliver excitation radiation to the treatment site. Further the medical device may include a radiation-receiving device configured to receive photoluminescence radiation emitted from the treatment site in response to the treatment site being illuminated by the excitation radiation and to generate a detection signal in response to the received photoluminescence radiation. Additionally, the excitation radiation may be different from the ablation energy.

Abstract: A measuring method for optically determining a distance (z) of a surface located in a medium from an end of an optical waveguide is described and has the following steps: emitting electromagnetic measuring radiation of a first wavelength (?1) and of a second wavelength (?2) from the end of the waveguide towards the surface, wherein the medium more strongly absorbs the electromagnetic measuring radiation of the second wavelength (?2) than the electromagnetic measuring radiation of the first wavelength (?1); measuring a first reflection signal (I1) of the electromagnetic measuring radiation of the first wavelength (?1) reflected from the surface, and measuring a second reflection signal (I2) of the electromagnetic measuring radiation of the second wavelength (?2) reflected from the surface, and determining the distance (z) from a ratio (I2:I1) of the second and the first reflection signal. Furthermore, a measuring device and a laser lithotripsy device are described.

Abstract: A medical device may include an ablation device configured to deliver ablation energy to a treatment site. The medical device may further include a probe device configured to deliver excitation radiation to the treatment site. Further the medical device may include a radiation-receiving device configured to receive photoluminescence radiation emitted from the treatment site in response to the treatment site being illuminated by the excitation radiation and to generate a detection signal in response to the received photoluminescence radiation. Additionally, the excitation radiation may be different from the ablation energy.

Abstract: A medical device may include an ablation device configured to deliver ablation energy to a treatment site. The medical device may further include a probe device configured to deliver excitation radiation to the treatment site. Further the medical device may include a radiation-receiving device configured to receive photoluminescence radiation emitted from the treatment site in response to the treatment site being illuminated by the excitation radiation and to generate a detection signal in response to the received photoluminescence radiation. Additionally, the excitation radiation may be different from the ablation energy.

Abstract: A method and a system for detecting a movement of a surface on an irradiated sample involves a light source for irradiating the surface with a coherent light beam, a detector for detecting variations caused by the movement in a speckle pattern produced by reflections of the light beam at the surface, selecting a single speckle from the speckle pattern, and detecting the variations at the selected speckle.

Abstract: A medical device may include an ablation device configured to deliver ablation energy to a treatment site. The medical device may further include a probe device configured to deliver excitation radiation to the treatment site. Further the medical device may include a radiation-receiving device configured to receive photoluminescence radiation emitted from the treatment site in response to the treatment site being illuminated by the excitation radiation and to generate a detection signal in response to the received photoluminescence radiation. Additionally, the excitation radiation may be different from the ablation energy.

Abstract: The invention relates to a method for photoacoustic tomography of a sample, deformations on a measurement surface of the sample being measured as a function of location and time, the deformations resulting from the absorption of a pulsed excitation radiation on at least one spectrally addressable target structure in the sample interior while emitting thermomechanical pressure waves in the direction of the measurement surface, and the measured deformations being fed to a reconstruction method for determining the position of the target structure in the sample interior.

Abstract: A therapeutic laser with a source of pulsed electromagnetic radiation, a control device for controlling the intensity and/or the duration of the therapeutic laser applied to the tissue, and a detection device for detecting optoacoustic signals triggered by irradiating the living tissue with the pulsed electromagnetic radiation. The therapeutic laser is characterized by an evaluation device that acts on the control device and is used for calculating a degree of quality B(t) from the optoacoustic signals detected by the detection device for individual laser pulses applied to a predetermined laser spot and determining a fit function f(t) at a predetermined point in time ?t1, the fit function f(t) approximating the mean curve of B(t) for 0?t??t1. The intensity and/or the irradiation time of the therapeutic laser is defined by the parameters for the predetermined laser spot, the parameters being determined for the fit function f(t).

Abstract: A method and a system for detecting a movement of a surface on an irradiated sample involves a light source for irradiating the surface with a coherent light beam, a detector for detecting variations caused by the movement in a speckle pattern produced by reflections of the light beam at the surface, selecting a single speckle from the speckle pattern, and detecting the variations at the selected speckle.

Abstract: The invention relates to a method for photoacoustic tomography of a sample, deformations on a measurement surface of the sample being measured as a function of location and time, the deformations resulting from the absorption of a pulsed excitation radiation on at least one spectrally addressable target structure in the sample interior while emitting thermomechanical pressure waves in the direction of the measurement surface, and the measured deformations being fed to a reconstruction method for determining the position of the target structure in the sample interior.

Abstract: A device for examining or treating living tissue by means of local heating of the tissue by absorbing electromagnetic radiation, with at least one radiation source emitting electromagnetic radiation, a control unit for controlling the irradiation parameters of the radiation source, and at least one FD-OCT apparatus with a light source emitting a measurement light for illuminating that tissue region in which the electromagnetic radiation is absorbed by the tissue, characterized by a computational unit for carrying out the following steps: determining the depth-resolved tissue velocity in the radiation direction of the measurement light at a predetermined measurement point of the tissue from the phase information from the FD-OCT interference light, integrating the established tissue velocity over time, differentiating the calculated time integral with respect to space, and displaying the spatial derivative as a function of space and time and/or feeding the spatial derivative as a function of space and time to a

Abstract: An apparatus for the treatment of biological, in particular living tissue comprising a treatment laser device 1 for generating a pulsed treatment radiation directed on to a target tissue, in an embodiment additionally including a measurement laser device 2, 3 for generating a pulsed measurement radiation directed on to the target tissue of lower energy and shorter pulse duration than the treatment radiation, a detector device 4 for measuring pressure transients induced by the measurement radiation and a control device 6 for controlling the treatment radiation in dependence on the pressure transients evaluated in respect of a tissue change, wherein a regulating or control algorithm for controlling the treatment radiation is formed from the pressure transients.

Abstract: A device for examining or treating living tissue by means of local heating of the tissue by absorbing electromagnetic radiation, with at least one radiation source emitting electromagnetic radiation, a control unit for controlling the irradiation parameters of the radiation source, and at least one FD-OCT apparatus with a light source emitting a measurement light for illuminating that tissue region in which the electromagnetic radiation is absorbed by the tissue, characterized by a computational unit for carrying out the following steps: determining the depth-resolved tissue velocity in the radiation direction of the measurement light at a predetermined measurement point of the tissue from the phase information from the FD-OCT interference light, integrating the established tissue velocity over time, differentiating the calculated time integral with respect to space, and displaying the spatial derivative as a function of space and time and/or feeding the spatial derivative as a function of space and time to a

Abstract: An apparatus for the treatment of biological, in particular living tissue comprising a treatment laser device 1 for generating a pulsed treatment radiation directed on to a target tissue, in an embodiment additionally including a measurement laser device 2, 3 for generating a pulsed measurement radiation directed on to the target tissue of lower energy and shorter pulse duration than the treatment radiation, a detector device 4 for measuring pressure transients induced by the measurement radiation and a control device 6 for controlling the treatment radiation in dependence on the pressure transients evaluated in respect of a tissue change, wherein a regulating or control algorithm for controlling the treatment radiation is formed from the pressure transients.

Abstract: This invention relates to a method for operation of an irradiation laser whereby laser pulse sequences or pulses of varying length are modified during application such that the comparability of recorded transients is retained.

Abstract: Disclosed is an apparatus for treating living tissue with laser, comprising a therapeutic laser with a source of pulsed electromagnetic radiation, a control device for controlling the intensity and/or the duration of the therapeutic laser applied to the tissue, and a detection device for detecting optoacoustic signals triggered by irradiating the living tissue with the pulsed electromagnetic radiation. Said apparatus is characterized by an evaluation device that acts on the control device and is used for calculating a degree of quality B(t) from the optoacoustic signals detected by the detection device for individual laser pulses applied to a predetermined laser spot and determining a fit function f(t) at a predetermined point in time ?tl, said fit function f(t) approximating the mean curve of B(t) for 0 =t =?tl.; The intensity and/or the irradiation time of the therapeutic laser is defined by the parameters for the predetermined laser spot, said parameters being determined for the fit function f(t).

Abstract: A method and a system for the non-invasive temperature determination on biological tissue, particularly at the fundus of the eye, treated by a treatment radiation, particularly laser radiation, wherein, during the respective irradiation time, at essentially identical time intervals, additional radiation pulses of a shorter pulse duration and a lower energy are aimed at the treated biological tissue, the resulting tissue expansions and/or contractions being detected by a pressure measurement or optical measurement and, from the measuring signals, the absolute temperature values are determined and optionally the treatment radiation is controlled as a function thereof.

Abstract: A method and a system for the non-invasive temperature determination on biological tissue, particularly at the fundus of the eye, treated by a treatment radiation, particularly laser radiation, wherein, during the respective irradiation time, at essentially identical time intervals, additional radiation pulses of a shorter pulse duration and a lower energy are aimed at the treated biological tissue, the resulting tissue expansions and/or contractions being detected by a pressure measurement or optical measurement and, from the measuring signals, the absolute temperature values are determined and optionally the treatment radiation is controlled as a function thereof.