Patents by Inventor Ralf D. Schoepfer

Ralf D. Schoepfer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Recombinant DNA encoding neuronal .alpha.-bungarotoxin-binding proteins
    Patent number: 5599709
    Abstract: An isolated DNA molecule encoding an .alpha.-bungarotoxin-binding protein (.alpha.BgtBP) subtype or a fragment of such .alpha. subunit is provided. The fragment of the .alpha. subunit is sufficiently homologous to specified DNA (FIG. 2A or FIG. 2B) so as to hybridize thereto under conditions of low stringency. Identification, characterization, isolation and sequencing of cDNA clones which encode two neuronal .alpha.BgtBP subunits, .alpha.1 and .alpha.2, is made possible. Such clones may be used as probes to identify further neuronal .alpha.BgtBP subunits, or as diagnostic tools to screen cholinergic agents and other drugs that may affect ligand binding, ion channel or other activity of intact neuronal .alpha.BgtBP subtypes.
    Type: Grant
    Filed: September 28, 1989
    Date of Patent: February 4, 1997
    Assignee: The Salk Institute for Biological Studies
    Inventors: Jon M. Lindstrom, Ralf D. Schoepfer