Patents by Inventor Ralf Devant

Ralf Devant has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 4-amino-quinazolines
    Patent number: 7829566
    Abstract: Quinazolines of the formula I in which R, R1, R2, R3, R4 and Y have the meaning indicated in Patent Claim 1, and their salts or solvates as glycoprotein IbIX antagonists.
    Type: Grant
    Filed: December 14, 2005
    Date of Patent: November 9, 2010
    Inventors: Werner Mederski, Ralf Devant, Gerhard Barnickel, Sabine Bernotat-Danielowski, James Vickers, Bertram Cezanne, Daljit Dhanoa, Bao-Ping Zhao, James Rinker, Mark R. Player, Edward Jaeger, Richard Soll
  • Use of substituted aminomethyl chromans
    Patent number: 7618988
    Abstract: Compounds of formula I in which R has a meaning as indicated in claim 1, or one of their optical isomers or pharmaceutically acceptable salts, used for the treatment of extrapyramidal movement disorders and/or adverse effects in extrapyramidal movement disorders and/or for the treatment of extrapyramidal symptoms (EPS) induced by neuroleptics.
    Type: Grant
    Filed: August 12, 2002
    Date of Patent: November 17, 2009
    Assignee: Merck Patentgesellschaft
    Inventors: Henning Böttcher, Ralf Devant, Maria Devant, legal representative, Gerd Bartoszyk, Hermann Russ, Frank Weber, Christoph Seyfried
  • 4-amino-quinazolines
    Patent number: 7547702
    Abstract: Quinazolines of the formula (I) in which R, R1, R2, R3, R4 and Y have the meaning indicated in Patent claim 1, and their salts or solvates as glycoprotein 1bIX antagonists.
    Type: Grant
    Filed: September 17, 2001
    Date of Patent: June 16, 2009
    Assignee: Ortho-McNeil Pharmaceutical, Inc.
    Inventors: Werner Mederski, Maria Devant, legal representative, Gerhard Barnickel, Sabine Bernotat-Danielowski, James Vickers, Bertram Cezanne, Daljit Dhanoa, Bao-Ping Zhao, James Rinker, Mark R. Player, Edward Jaegar, Richard Soll, Ralf Devant
  • 4-Amino-quinazolines
    Publication number: 20070293667
    Abstract: Quinazolines of the formula I in which R, R1, R2, R3, R4 and Y have the meaning indicated in Patent Claim 1, and their salts or solvates as glycoprotein IbIX antagonists.
    Type: Application
    Filed: December 14, 2005
    Publication date: December 20, 2007
    Inventors: Werner Mederski, Ralf Devant, Gerhard Barnickel, Sabine Bernotat-Danielowski, James Vickers, Bertram Cezanne, Daljit Dhanoa, Bao-Ping Zhao, James Rinker, Mark Player, Edward Jaeger, Richard Soll
  • Novel use of substituted aminomethyl chromans
    Publication number: 20060229339
    Abstract: Compounds of formula I in which R has a meaning as indicated in claim 1, or one of their optical isomers or pharmaceutically acceptable salts, used for the treatment of extrapyramidal movement disorders and/or adverse effects in extrapyramidal movement disorders and/or for the treatment of extrapyramidal symptoms (EPS) induced by neuroleptics.
    Type: Application
    Filed: August 12, 2002
    Publication date: October 12, 2006
    Inventors: Henning Böttcher, Ralf Devant, Maria Devant, Gerd Bartoszyk, Hermann Russ, Frank Weber, Christoph Seyfried
  • Quinazolinones
    Patent number: 7060706
    Abstract: Quinazolinones of formula (I) in which R, R1, R2, R3, R4, Y, n and m have the meaning indicated in Patent claim 1, and their salts or solvates as glycoprotein IbIX antagonists
    Type: Grant
    Filed: September 13, 2000
    Date of Patent: June 13, 2006
    Assignee: 3-Dimensional Pharmaceuticals, Inc.
    Inventors: Werner Mederski, Ralf Devant, Gerhard Barnickel, Sabine Bernotat-Danielowski, Guido Melzer, Bertram Cezanne, Daljit Dhanoa, Bao-Ping Zhao, James Rinker, Mark Player, Richard Soll
  • Method for producing-2[-5-(4-fluorophenyl)-3-pyridylmethylaminomethyl]-chromane
    Patent number: 7045629
    Abstract: The present invention relates to a process for the preparation of 2-[5-(4-fluorophenyl)-3-pyridylmethylaminomethyl]chroman, the enantiomers and its salts, characterised in that 5-(4-fluorophenyl)pyridine-3-carbaldehyde is reacted directly with aminomethylchroman or its salts under reducing conditions to give 2-[5-(4-fluorophenyl)-3-pyridylmethylaminomethyl]chroman, and the latter is, if desired, converted into one of its physiologically acceptable salts by treatment with an acid.
    Type: Grant
    Filed: April 8, 2002
    Date of Patent: May 16, 2006
    Assignee: Merck Patent GmbH
    Inventors: Heinz-Hermann Bokel, Steffen Neuenfeld, Ludwig Gantzert, Ralf Knierieme, Elke Simon, Ralf Devant, Udo Helm, Helmut Reubold
  • 4-Amino-quinazolines
    Publication number: 20060019974
    Abstract: Quinazolines of the formula (I) in which R, R1, R2, R3, R4 and Y have the meaning indicated in Patent claim 1, and their salts or solvates as glycoprotein IbIX antagonists.
    Type: Application
    Filed: September 17, 2001
    Publication date: January 26, 2006
    Inventors: Werner Mederski, Ralf Devant, Maria Devant, Gerhard Barnickel, Sabine Bernotat-Danielowski, James Vickers, Bertram Cezanne, Daljit Dhanoa, Bao-Ping Zhao, James Rinker, Mark Player, Edward Jaeger, Richard Soll
  • Quinazolinones
    Patent number: 6890930
    Abstract: Quinazolinones of formula (I) in which R, R1, R2, R3, R4, Y, Z, and m have the meaning indicated in patent claim 1, and their salts or solvates as glycoprotein IbIX antagonists.
    Type: Grant
    Filed: September 13, 2000
    Date of Patent: May 10, 2005
    Assignee: 3-Dimensional Pharmaceuticals, Inc.
    Inventors: Werner Mederski, Maria Devant, Gerhard Barnickel, Sabine Bernotat-Danielowski, Guido Melzer, Bertram Cezane, Dalijit Dhanoa, Bao-Ping Zhoa, James Rinker, Mark Player, Richard Soll, Ralf Devant
  • Method for producing-2[-5-(4-fluorophenyl)-3-pyridylmethylaminomethyl]-chromane
    Publication number: 20040138266
    Abstract: The present invention relates to a process for the preparation of 2-[5-(4-fluorophenyl)-3-pyridylmethylaminomethyl]chroman, the enantiomers and its salts, characterised in that 5-(4-fluorophenyl)pyridine-3-carbaldehyde is reacted directly with aminomethylchroman or its salts under reducing conditions to give 2-[5-(4-fluorophenyl)-3-pyridylmethylaminomethyl]chroman, and the latter is, if desired, converted into one of its physiologically acceptable salts by treatment with an acid.
    Type: Application
    Filed: October 27, 2003
    Publication date: July 15, 2004
    Inventors: Heinz-Hermann Bokel, Steffen Neuenfeld, Ludwig Gantzert, Ralf Knierieme, Elke Simon, Ralf Devant, Udo Helm, Helmut Reubold
  • 4-amino-quinazolines
    Publication number: 20040044204
    Abstract: Quinazolines of the formula I, in which R, R1, R2, R3, R4 and Y have the meaning indicated in Patent claim 1, and their salts or solvates as glycoprotein IbIX antagonists.
    Type: Application
    Filed: March 20, 2003
    Publication date: March 4, 2004
    Inventors: Werner Mederski, Ralf Devant, Gerhard Barnickel, Sabine Bernotat-Danielowski, James Vickers, Bertram Cezanne, Daljit Dhanoa, Bao-Ping Zhao, James Rinker, Mark R Player, Edward Jaeger, Richard Soll
  • Pyridyl chroman
    Patent number: 5767132
    Abstract: Amino(thio)ether derivatives of formula I ##STR1## wherein R.sup.0, R.sup.1, R.sup.2, R.sup.3, R.sup.6, R.sup.7, R.sup.8, R.sup.9, X and Z are as defined herein, and their salts, are active on the central nervous system.
    Type: Grant
    Filed: October 16, 1995
    Date of Patent: June 16, 1998
    Assignee: Merck Patent Gesellschaft Mit Beschrankter Haftung
    Inventors: Henning Bottcher, Ralf DeVant, Hartmut Greiner, Gerd Bartoszyk, Jean-Jacques Berthelon, Marc Noblet, Jean-Jacques Zeiller, Michel Brunet
  • Process for the resolution of enantiomers of benzopyran derivatives
    Patent number: 5103025
    Abstract: The invention relates to a process for the resolution of enantiomers of 3,4-epoxy-3,4-dihydro-2,2-dimethyl-3-R-2H-1-benzopyran-6-carbonitriles (I), in which R is H or CH.sub.3, characterized in that racemic I is dissolved in an inert solvent or solvent mixture together with a small amount of (-)-I [or (+)-I], the solution is seeded with (-)-I [or (+)-I], the precipitated (-)-I [or (+)-I] is isolated, further racemic I is dissolved in the filtrate, seeded with (+)-I [or (-)-I], the precipitated (+)-I [or (-)-I] is isolated and, if desired, this crystallization cycle is repeated one or more times.
    Type: Grant
    Filed: November 2, 1990
    Date of Patent: April 7, 1992
    Assignee: Merck Patent Gesellschaft Mit Beschrankter Haftung
    Inventors: Ralf Devant, Rolf Gericke