Abstract: The various embodiments described herein include methods, devices, and systems for customizing dental care. In one aspect, a personalized dental care device includes a first customized mouthpiece including a top cleaning tray and a bottom cleaning tray, each customized based at least in part on an electronic 3-D dental model of a respective user's mouth. The personalized dental care device includes one or more power mechanisms, configured to couple with the first customized mouthpiece, and to transmit energy to at least one cleaning tray of the first customized mouthpiece. The personalized dental care device is configured to be operated in a plurality of modes. Each respective mode of the plurality of modes is associated with a different method for providing oral care.