Patents by Inventor Ralf Heim

Ralf Heim has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11167933
    Abstract: A method for transferring medical products comprises the steps of conveying medical products on an oscillating conveyor having a plurality of conveying lanes arranged next to each other to a delivery area of the conveyor lanes and from the delivery area into at least one shaft; detecting a defective product in one of the conveying lanes; and activating a diverter device for defective products, which is arranged adjacent to the delivery area of this conveying lane, when a defective product is detected, wherein the diverter device, upon activation, is shifted or pivoted into an activated position, in which the diverter device is located in a transport path of the defective product.
    Type: Grant
    Filed: June 19, 2020
    Date of Patent: November 9, 2021
    Assignee: Uhlmann Pac-Systeme Gmb H & Co. KG
    Inventors: Ralf Heim, Michael Kronawitter
  • Publication number: 20200399074
    Abstract: A method for transferring medical products comprises the steps of conveying medical products on an oscillating conveyor having a plurality of conveying lanes arranged next to each other to a delivery area of the conveyor lanes and from the delivery area into at least one shaft; detecting a defective product in one of the conveying lanes; and activating a diverter device for defective products, which is arranged adjacent to the delivery area of this conveying lane, when a defective product is detected, wherein the diverter device, upon activation, is shifted or pivoted into an activated position, in which the diverter device is located in a transport path of the defective product.
    Type: Application
    Filed: June 19, 2020
    Publication date: December 24, 2020
    Inventors: Ralf Heim, Michael Kronawitter
  • Patent number: 10336516
    Abstract: Childproof safety cap has two opposite bead-like threads on its inner wall. Each thread has a widened end region, a stop surface thus being formed. The associated bottle has two opposite groove-like threads on a connecting piece of the bottle, each of which threads has a widened region in the end region, an undercut thus being formed in the groove by the widened region. When the safety cap is screwed on, the stop surfaces on the two bead-like threads hook in behind the undercuts on the groove-like threads. The stop surfaces can be released from each other only if the safety cap is pressed down toward the bottle onto the connecting-piece neck. Connecting-piece neck forms a slipping surface that conically expands downwards. The safety cap can then be unscrewed while simultaneously being rotated.
    Type: Grant
    Filed: December 17, 2015
    Date of Patent: July 2, 2019
    Assignee: AERO PUMP GMBH
    Inventors: Ralf Heim, Andreas Mersmann
  • Publication number: 20180016067
    Abstract: Childproof safety cap having two opposite bead-like threads on its inner wall. Each thread has a widened end region, a stop surface thus being formed. The associated bottle has two opposite groove-like threads on a connecting piece of said bottle, each of which threads has a widened region in the end region, an undercut thus being formed in the groove by the widened region. When the safety cap is screwed on, the stop surfaces on the two bead-like threads hook in behind the undercuts on the groove-like threads. The stop surfaces can be released from each other only if the safety cap is pressed down toward the bottle onto the connecting-piece neck. Connecting-piece neck forms a slipping surface that conically expands downwards. The safety cap can then be unscrewed while simultaneously being rotated.
    Type: Application
    Filed: December 17, 2015
    Publication date: January 18, 2018
    Applicant: AERO PUMP GMBH
    Inventors: Ralf HEIM, Andreas MERSMANN
  • Patent number: 9745282
    Abstract: This invention relates to indoline compounds of the structural formula: or their pharmaceutically acceptable salts, wherein the variables are defined herein. The inventive compounds selectively inhibit aldosterone synthase. This invention also provides for pharmaceutical compositions comprising the compounds of Formula I or their salts as well as potentially to methods for the treatment, amelioration or prevention of conditions that could be treated by inhibiting aldosterone synthase.
    Type: Grant
    Filed: June 30, 2016
    Date of Patent: August 29, 2017
    Assignees: Merck Sharp & Dohme Corp, ElexoPharm GmbH
    Inventors: Amjad Ali, Michael Man-Chu Lo, Edward Metzger, Lina Yin, Rolf Hartmann, Qingzhong Hu, Ralf Heim, Christina Zimmer
  • Patent number: 9550750
    Abstract: This invention relates to indo line compounds of the structural formula I, or their pharmaceutically acceptable salts, wherein the variables are defined herein. The inventive compounds selectively inhibit aldosterone synthase. This invention also provides for pharmaceutical compositions comprising the compounds of Formula I or their salts as well as potentially to methods for the treatment amelioration or prevention of conditions that could be treated by inhibiting aldosterone synthase.
    Type: Grant
    Filed: October 2, 2013
    Date of Patent: January 24, 2017
    Assignees: Merck Sharp & Dohme Corp., Elexopharm GMBH
    Inventors: Amjad Ali, Michael Man-Chu Lo, Edward Metzger, Lina Yin, Rolf Hartmann, Qingzhong Hu, Ralf Heim, Christina Zimmer
  • Publication number: 20160304486
    Abstract: This invention relates to indoline compounds of the structural formula: or their pharmaceutically acceptable salts, wherein the variables are defined herein. The inventive compounds selectively inhibit aldosterone synthase. This invention also provides for pharmaceutical compositions comprising the compounds of Formula I or their salts as well as potentially to methods for the treatment, amelioration or prevention of conditions that could be treated by inhibiting aldosterone synthase.
    Type: Application
    Filed: June 30, 2016
    Publication date: October 20, 2016
    Inventors: Amjad Ali, Michael Man-Chu Lo, Edward Metzger, Lina Yin, Rolf Hartmann, Qingzhong Hu, Ralf Heim, Christina Zimmer
  • Patent number: 9399532
    Abstract: The invention pertains to a system for filling bottle-like containers with tablets, which comprises various devices for specific processes, wherein most of the devices have a transport mechanism for positively guiding the movement of each container by itself in a continuous manner, whereas at least the device for dosing the pharmaceutical products and for introducing the pharmaceutical products into the containers has a transport mechanism for positively guiding the movement of each container by itself in a clocked manner in certain sections. The transport mechanisms of the devices are connected to each other in series, which ensures the positive guidance of each individual container by itself through the entire system.
    Type: Grant
    Filed: June 6, 2008
    Date of Patent: July 26, 2016
    Assignee: Uhlmann Pac-Systeme GmbH & Co. KG
    Inventors: Joachim Noe, Michael Kronawitter, Ralf Heim, Rita Hagel, Rolf Armbruster
  • Publication number: 20150225365
    Abstract: This invention relates to indo line compounds of the structural formula I, or their pharmaceutically acceptable salts, wherein the variables are defined herein. The inventive compounds selectively inhibit aldosterone synthase. This invention also provides for pharmaceutical compositions comprising the compounds of Formula I or their salts as well as potentially to methods for the treatment amelioration or prevention of conditions that could be treated by inhibiting aldosterone synthase.
    Type: Application
    Filed: October 2, 2013
    Publication date: August 13, 2015
    Applicants: ElexoPharm GmbH, Merck Sharp & Dohme Corp.
    Inventors: Amjad Ali, Michael Man-Chu Lo, Edward Metzger, Lina Yin, Rolf Hartmann, Qingzhong Hu, Ralf Heim, Christina Zimmer
  • Patent number: 9073929
    Abstract: This invention relates to tricyclic triazole analogs of the formula I or their pharmaceutically acceptable salts, wherein the variable are defined herein. The inventive compounds selectively inhibit aldosterone synthetase. This invention also provides for pharmaceutical compositions comprising the compounds of Formula I or their salts as well as to methods for the treatment, amelioration or prevention of conditions that could be treated by inhibiting aldosterone synthetase.
    Type: Grant
    Filed: April 20, 2012
    Date of Patent: July 7, 2015
    Assignees: ElexoPharm GmbH, Merck Sharp & Dohme Corp.
    Inventors: Scott B. Hoyt, Whitney Lane Petrilli, Clare London, Yusheng Xiong, Jerry Andrew Taylor, Amjad Ali, Michael Man-Chu Lo, Timothy J. Henderson, Qingzhong Hu, Rolf Hartmann, Lina Yin, Ralf Heim, Emmanuel Bey, Rohit Saxena, Swapan Kumar Samanta, Bheemashankar A. Kulkarni
  • Patent number: 8685960
    Abstract: The invention provides compounds of the general formula (I) which are inhibitors of the human aldosterone synthase, and also pharmaceutical compositions containing these compounds, and the use of these compounds and other heteroaryl substituted quinolinone derivatives for the treatment of hyperaldosteronism and/or disorders or diseases that are mediated by 11 ?-hydroxylase (CYP11 B1).
    Type: Grant
    Filed: May 5, 2009
    Date of Patent: April 1, 2014
    Assignee: Elexopharm GmbH
    Inventors: Rolf W. Hartmann, Ralf Heim, Simon Lucas
  • Patent number: 8678175
    Abstract: The device for channeling out upright containers from a first transport device, which moves the container in a transport direction, includes a lateral guide section, which extends in the transport direction, and a gripper unit, which has a plurality of grippers for gripping the containers. The lateral guide section and the gripper unit are moved from a pickup position for the containers jointly in a direction transverse to the transport direction. After this joint movement the gripper unit is moved towards a discharge position for the containers. The lateral guide section and the gripper unit are then moved back to the pickup position.
    Type: Grant
    Filed: February 9, 2012
    Date of Patent: March 25, 2014
    Assignee: Uhlmann Pac-Systeme GmbH & Co. KG.
    Inventors: Ralf Heim, Joachim Noe
  • Publication number: 20140045819
    Abstract: This invention relates to tricyclic triazole analogues of the formula I or their pharmaceutically acceptable salts, wherein the variable are defined herein. The inventive compounds selectively inhibit aldosterone synthetase. This invention also provides for pharmaceutical compositions comprising the compounds of Formula I or their salts as well as to methods for the treatment, amelioration or prevention of conditions that could be treated by inhibiting aldosterone synthetase.
    Type: Application
    Filed: April 20, 2012
    Publication date: February 13, 2014
    Applicants: ElexoPharm GmbH, SCHERING CORPORATION
    Inventors: Scott B. Hoyt, Whitney Lane Petrilli, Clare London, Yusheng Xiong, Jerry Andrew Taylor, Amjad Ali, Michael Man-Chu Lo, Timothy J. Henderson, Qingzhong Hu, Rolf Hartmann, Lina Yin, Ralf Heim, Emmanuel Bey, Rohit Saxena, Swapan Kumar Samanta, Bheemashankar A. Kulkarni
  • Patent number: 8541404
    Abstract: The invention provides compounds of the general formula (I) which are inhibitors of the human aldosterone synthase, and also pharmaceutical compositions containing these compounds, and a method of treating of hyperaldosteronism and/or disorders or diseases that are mediated by 11?-hydroxylase (CYP11B1) with these compounds.
    Type: Grant
    Filed: November 3, 2010
    Date of Patent: September 24, 2013
    Assignee: ElexoPharm GmbH
    Inventors: Rolf W. Hartmann, Ralf Heim, Simon Lucas
  • Patent number: 8534453
    Abstract: The device for transporting upright containers in a straight line includes a rake conveyor comprising multiple receiving sections for the containers and an opposing support element for the containers carried in the receiving sections. The rake conveyor is connected to two drives by at least two pivot systems, each with two arms, in such a way that the rake conveyor can be pushed back and forth both in the transport direction of the containers and also in the direction perpendicular to the transport direction of the containers.
    Type: Grant
    Filed: February 9, 2012
    Date of Patent: September 17, 2013
    Assignee: Uhlmann Pac-Systeme GmbH & Co. KG
    Inventors: Juergen Liebhardt, Michael Kronawitter, Ralf Heim
  • Patent number: 8403009
    Abstract: A method for filling a plurality of containers in cycles at a predetermined number of stationary filling units arranged in a row with a first spacing from each other. The method includes providing a plurality of positively guided containers in a row, one-by-one, wherein the containers have a uniform second spacing from each other, wherein the first spacing of the individual filling units is a whole-number multiple of the second spacing of the containers, and filling a predetermined number of the containers simultaneously at the filling units. The containers are shifted in cycles along the filling units in a transport direction by a step length, which is a whole-number multiple of the second spacing of the containers and which is shorter than a third spacing between a first filling unit and a last filling unit steps of filling and shifting are repeated over a predetermined number of iterations.
    Type: Grant
    Filed: August 10, 2009
    Date of Patent: March 26, 2013
    Assignee: Uhlmann Pac-Systems GmbH & Co. KG
    Inventors: Joachim Noe, Thomas Ruelker, Ralf Heim
  • Publication number: 20120222939
    Abstract: The device for channeling out upright containers from a first transport device, which moves the container in a transport direction, includes a lateral guide section, which extends in the transport direction, and a gripper unit, which has a plurality of grippers for gripping the containers. The lateral guide section and the gripper unit are moved from a pickup position for the containers jointly in a direction transverse to the transport direction. After this joint movement the gripper unit is moved towards a discharge position for the containers. The lateral guide section and the gripper unit are then moved back to the pickup position.
    Type: Application
    Filed: February 9, 2012
    Publication date: September 6, 2012
    Applicant: UHLMANN PAC-SYSTEME GMBH & CO. KG.
    Inventors: Ralf Heim, Joachim Noe
  • Publication number: 20120222941
    Abstract: The device for transporting upright containers in a straight line includes a rake conveyor comprising multiple receiving sections for the containers and an opposing support element for the containers carried in the receiving sections. The rake conveyor is connected to two drives by at least two pivot systems, each with two arms, in such a way that the rake conveyor can be pushed back and forth both in the transport direction of the containers and also in the direction perpendicular to the transport direction of the containers.
    Type: Application
    Filed: February 9, 2012
    Publication date: September 6, 2012
    Applicant: UHLMANN PAC-SYSTEME GMBH & CO. KG
    Inventors: Juergen Liebhardt, Michael Kronawitter, Ralf Heim
  • Publication number: 20110118241
    Abstract: The invention provides compounds of the general formula (I) which are inhibitors of the human aldosterone synthase, and also pharmaceutical compositions containing these compounds, and the use of these compounds and other heteroaryl substituted quinolinone derivatives for the treatment of hyperaldosteronism and/or disorders or diseases that are mediated by 11 ?-hydroxylase (CYP11 B1).
    Type: Application
    Filed: May 5, 2009
    Publication date: May 19, 2011
    Applicant: Universitat des Saarlandes
    Inventors: Rolf W. Hartmann, Ralf Heim, Simon Lucas
  • Publication number: 20110112067
    Abstract: The invention provides compounds of the general formula (I) which are inhibitors of the human aldosterone synthase, and also pharmaceutical compositions containing these compounds, and a method of treating of hyperaldosteronism and/or disorders or diseases that are mediated by 11?-hydroxylase (CYP11B1) with these compounds.
    Type: Application
    Filed: November 3, 2010
    Publication date: May 12, 2011
    Applicant: Universitat des Saarlandes
    Inventors: Rolf W. Hartmann, Ralf Heim, Simon Lucas