Patents by Inventor Ralf Hofer

Ralf Hofer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240092853
    Abstract: The present invention generally relates to pH-dependent mutant interleukin-2 polypeptides that exhibit reduced IL-2 receptor binding at neutral pH and retained IL-2 receptor binding at reduced pH. In addition, the invention relates to immunoconjugates comprising said pH-dependent mutant IL-2 polypeptides, polynucleotide molecules encoding the pH-dependent mutant IL-2 polypeptides or immunoconjugates, and vectors and host cells comprising such polynucleotide molecules. The invention further relates to methods for producing the pH-dependent mutant IL-2 polypeptides or immunoconjugates, pharmaceutical compositions comprising the same, and uses thereof.
    Type: Application
    Filed: December 2, 2021
    Publication date: March 21, 2024
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Lorenzo DEHO, Christian GASSNER, Sylvia HERTER, Thomas HOFER, Ralf HOSSE, Adrian HUGENMATTER, Christian KLEIN, Florian LIMANI, Ekkehard MOESSNER, Melanie OBBA, Bianca SCHERER, Pablo UMANA
  • Publication number: 20030183705
    Abstract: The invention relates to a method for the dry separation of unsorted garbage that contains packaging waste consisting of plastic materials of various polymer groupings that includes the following steps: separation of the materials on the basis of differences in size; separation of the materials on the basis of differences in grain shape, grain size and/or specific weight; separation of the materials on the basis of differences in their magnetic properties; separation of the materials on the basis of differences in their electric properties; and separation of the materials on the basis of differences in their spectroscopic properties.
    Type: Application
    Filed: May 9, 2003
    Publication date: October 2, 2003
    Inventors: Joachim Christiani, Ralf Hofer