Patents by Inventor Ralf Kleene

Ralf Kleene has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TREATMENT OF NERVE INJURIES
    Publication number: 20120276073
    Abstract: This invention relates to treatment of nerve injuries and regeneration of nerves and nerve function in the acutely and chronically lesioned central and peripheral nervous system. The invention provides a pharmaceutical composition comprising histone, e.g., H1. It was surprisingly shown that histones, in particular histone H1, can be used for the preparation of a pharmaceutical composition for treatment and/or prevention of acute and chronic injuries to the central and peripheral nervous system, for promoting growth and/or regrowth of nerves and enhancing formation of synapses and synaptic plasticity, and for neuroprotection.
    Type: Application
    Filed: November 30, 2010
    Publication date: November 1, 2012
    Applicant: UNIVERSITÄTSKLINIKUM HAMBURG-EPPENDORF
    Inventors: Melitta Schachner, Ralf Kleene, Bibhudatta Mishra
  • Methods for diagnosing dementia-related neurological disorders
    Publication number: 20050019781
    Abstract: The current invention relates to methods for diagnosing and monitoring the progression of a dementia-related neurodegenerative disease in a patient suspected of having such a disease by determining the levels of at least one cell adhesion molecule.
    Type: Application
    Filed: August 22, 2003
    Publication date: January 27, 2005
    Inventors: Carsten Buhmann, John Hemperly, Ralf Kleene, Melitta Schachner, Helen Strekalova, Tomas Muller-Thomsen