Patents by Inventor Ralf Knieriemen

Ralf Knieriemen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for producing 5-aryl nicotinaldehydes
    Patent number: 6703509
    Abstract: The invention relates to a process for the preparation of 5-arylnicotinaldehydes by reduction of the corresponding 5-arylnicotinic acids by catalytic hydrogenation in the presence of carboxylic anhydrides in which the catalyst used is a palladium/ligand complex, characterized in that the molar ratio between palladium and ligand is from 1:5 to 1:15 in the case of monodentate ligands and from 1:2.5 to 1:7.5 in the case of bidentate ligands.
    Type: Grant
    Filed: August 6, 2002
    Date of Patent: March 9, 2004
    Assignee: Merck Patent GmbH
    Inventors: Andreas Bathe, Heinz Bokel, Thomas Keil, Ralf Knieriemen, Christoph Murmann
  • Method for producing 5-aryl nicotinaldehydes
    Publication number: 20030055259
    Abstract: The invention relates to a process for the preparation of 5-arylnicotinaldehydes by reduction of the corresponding 5-arylnicotinic acids by catalytic hydrogenation in the presence of carboxylic anhydrides in which the catalyst used is a palladium/ligand complex, characterized in that the molar ratio between palladium and ligand is from 1:5 to 1:15 in the case of monodentate ligands and from 1:2.5 to 1:7.5 in the case of bidentate ligands.
    Type: Application
    Filed: August 6, 2002
    Publication date: March 20, 2003
    Inventors: Andreas Bathe, Heinz Bokel, Thomas Keil, Ralf Knieriemen, Christoph Murmann
  • Method for producing 5-aryl nicotinaldehydes
    Patent number: RE41008
    Abstract: The invention relates to a process for the preparation of 5-arylnicotinaldehydes by reduction of the corresponding 5-arylnicotinic acids by catalytic hydrogenation in the presence of carboxylic anhydrides in which the catalyst used is a palladium/ligand complex, characterized in that the molar ratio between palladium and ligand is from 1:5 to 1:15 in the case of monodentate ligands and from 1:2.5 to 1:7.5 in the case of bidentate ligands.
    Type: Grant
    Filed: January 5, 2001
    Date of Patent: November 24, 2009
    Assignee: Merck Patent GmbH
    Inventors: Andreas Bathe, Heinz Bokel, Ralf Knieriemen, Christoph Muermann, Thomas Keil