Patents by Inventor Ralf Looser

Ralf Looser has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20090032462
    Abstract: The present invention relates to a process for extracting constituents from organic material, comprising the step of extracting with a monophasic mixture of 50% by volume to 90% by volume of methanol and 50 to 10% by volume of water and optionally 0% by volume to 40% by volume of a further solvent or solvent mixture.
    Type: Application
    Filed: October 1, 2008
    Publication date: February 5, 2009
    Applicant: Metanomics GmbH and Co. KGaA
    Inventors: Michael Manfred Herold, Martin Dostler, Ralf Looser, Tilmann B. Walk, Achim Fegert, Martin Kluttig, Britta Lehmann, Silke Heidemann, Annette Hennig, Joachim Kopka
  • Patent number: 7431841
    Abstract: The invention relates to a method for the extraction of components made from organic material, comprising the step of extraction with a single-phase mixture of 50 to 90 vol. % methanol and 50 to 10 vol. % water and optionally 0 to 40 vol. % of a further solvent or solvent mixture.
    Type: Grant
    Filed: November 11, 2002
    Date of Patent: October 7, 2008
    Assignee: Metanomics GmbH & Co. KGaA
    Inventors: Michael Manfred Herold, Martin Dostler, Ralf Looser, Tilmann B. Walk, Achim Fegert, Martin Kluttig, Britta Lehmann, Silke Heidemann, Annette Hennig, Joachim Kopka
  • Publication number: 20080234945
    Abstract: The present invention relates to a method for analyzing at least one test sample, wherein said test sample comprises at least one compound, said method comprising the steps of: a) providing at least one test sample comprising at least one compound; b) determining said at least one compound in said test sample whereby raw results are generated; and c) analyzing the raw results obtained in step b), wherein the analysis of said at least one test sample is accompanied by an analysis of at least one reference sample; and wherein the test sample and the reference sample are analyzed in an identical sequence in each step of the method.
    Type: Application
    Filed: July 25, 2006
    Publication date: September 25, 2008
    Applicant: METANOMICS GMBH
    Inventors: Tilmann B. Walk, Ralf Looser, Bianca Bethan, Michael Manfred Herold, Beate Kamlage, Oliver Schmitz, Jan C Wiemer, Alexandre Prokoudine, Bennard van Ravenzwaay, Werner Mellert, Georgia Coelho Palermo Cunba, Thomas Ehrhardt, Gerhard Krennrich
  • Publication number: 20080153928
    Abstract: The present invention relates to a method for providing an animal population having an essentially identical metabolome comprising compiling an animal population being of essentially the same age, keeping said animal population for a time period sufficient for acclimatization under the following housing conditions: (i) constant temperature, (ii) constant humidity, (iii) physical separation of the animals of the animal population, (iv) feeding ad libitum, wherein the food to be fed is essentially free of chemical or microbial contaminance, (v) drinking libitum, wherein the drinking liquid is essentially free of chemical or microbial contaminance, (vi) constant illumination period, and providing the animal population after said time period. Further, the present invention relates to methods for the identification of a compound which effects the metabolome of an animal, or methods for the identification of a marker for such compounds.
    Type: Application
    Filed: July 10, 2006
    Publication date: June 26, 2008
    Applicant: BASF Aktiengesellschaft
    Inventors: Bennard van Ravenzwaay, Georgia Coelho Palermo Cunha, Werner Mellert, Ralf Looser, Tilmann B. Walk, Jan C. Wiemer, Volker Haake
  • Patent number: 7311838
    Abstract: The present invention relates to a process for isolating constituents from organic material, comprising the following process steps: a) freeze-drying of the organic material; b) extracting the constituents with a polar solvent or solvent mixture (A) and an organic solvent or solvent mixture (B), it being possible for the extracts of the extraction with (A) and (B) to form one phase; c) combining the extracts (A) and (B) to give one phase; and d) carrying out an esterification/transesterification in the unpolar phase with an alcohol, the esterification/transesterification being carried out in the presence of a volatile acid; the process being a high-throughput process.
    Type: Grant
    Filed: November 11, 2002
    Date of Patent: December 25, 2007
    Assignee: Metanomics GmbH & Co. KGaA
    Inventors: Michael Manfred Herold, Martin Dostler, Ralf Looser, Tilmann B. Walk, Achim Fegert, Martin Kluttig, Britta Lehmann, Silke Heidemann, Annette Hennig, Joachim Kopka
  • Publication number: 20070118916
    Abstract: The present invention relates to a process for the production of the fine chemical in a microorganism, a plant cell, a plant, a plant tissue or in one or more parts thereof, preferably in plastids. The invention furthermore relates to nucleic acid molecules, polypeptides, nucleic acid constructs, vectors, antibodies, host cells, plant tissue, propagation material, harvested material, plants, microorganisms as well as agricultural compositions and to their use.
    Type: Application
    Filed: September 6, 2006
    Publication date: May 24, 2007
    Applicant: Metanomics GmbH
    Inventors: Piotr Puzio, Birgit Wendel, Michael Herold, Ralf Looser, Astrid Blau, Gunnar Plesch, Beate Kamlage, Florian Schauwecker
  • Publication number: 20060137042
    Abstract: The present invention relates to a process for the production of the fine chemical in a microorgansm, a plant cell, a plant, a plant tissue or in one or more parts thereof. The invention furthermore relates to nucleic acid molecules, polypeptides, nucleic acid constructs, vectors, antisense molecules, antibodies, host cells, plant tissue, propagtion material, harvested material, plants, microorganisms as well as agricultural compositions and to their use.
    Type: Application
    Filed: July 21, 2004
    Publication date: June 22, 2006
    Applicant: BASF Plant Science GmbH
    Inventors: Gunnar Plesch, Piotr Puzio, Astrid Blau, Ralf Looser, Birgit Wendel, Beate Kamlage, Agnes Chardonnens, Amber Shirley, Xi-Qing Wang, Rodrigo Sarria-Millan, Bryan McKersie, Ruoying Chen
  • Publication number: 20060117401
    Abstract: The invention relates to a method for producing aminoacids in transgenic organisms. The inventive method consists of the following steps: a) introduction of nucleic acids sequence which codes threonine decomposing protein or lysine decomposing protein or codes threonine decomposing protein and lysine decomposing protein, b) introduction of nucleic acids sequence which improves the decomposition of threonine or lysine or the decomposition of threonine and lysine in the transgenic organisms; c) expression of (a) or (b) nucleic acids sequence in a transgenic organism.
    Type: Application
    Filed: December 19, 2003
    Publication date: June 1, 2006
    Inventors: Oliver Schmitz, Piotr Puzio, Astrid Blau, Ralf Looser, Birgit Wendel, Beate Kamlage, Gunnar Plesch
  • Publication number: 20040262221
    Abstract: The present invention relates to a process for isolating constituents from organic material, comprising the following process steps:
    Type: Application
    Filed: May 5, 2004
    Publication date: December 30, 2004
    Inventors: Michael Manfred Herold, Martin Dostler, Ralf Looser, Tilmann B. Walk, Achim Fegert, Martin Kluttig, Britta Lehmann, Silke Heidemann, Annette Hennig, Joachim Kopka
  • Publication number: 20040260105
    Abstract: The invention relates to a method for the extraction of components made from organic material, comprising the step of extraction with a single-phase mixture of 50 to 90 vol. % methanol and 50 to 10 vol. % water and optionally 0 to 40 vol. % of a further solvent or solvent mixture.
    Type: Application
    Filed: May 5, 2004
    Publication date: December 23, 2004
    Inventors: Michael Manfred Herold, Martin Dostler, Ralf Looser, Tilmann B. Walk, Achim Fegert, Martin Kluttig, Britta Lehmann, Silke Heidemann, Annette Hennig, Joachim Kopka