Patents by Inventor Ralf Lotz

Ralf Lotz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Alkyne compounds with MCH antagonistic activity and medicaments comprising these compounds
    Publication number: 20050267115
    Abstract: Alkyne compounds of formula I wherein A, B, W, X, Y, Z, R1, and R2 have the meanings given herein, which have MCH-receptor antagonistic activity and are useful for preparing pharmaceutical compositions for the treatment of metabolic disorders and/or eating disorders, particularly obesity and diabetes.
    Type: Application
    Filed: April 13, 2005
    Publication date: December 1, 2005
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Dirk Stenkamp, Stephan Mueller, Philipp Lustenberger, Thorsten Lehmann-Lintz, Gerald Roth, Klaus Rudolf, Marcus Schindler, Leo Thomas, Ralf Lotz
  • Amide compounds with MCH antagonistic activity and medicaments comprising these compounds
    Publication number: 20050267093
    Abstract: Compounds of formula (I) wherein A, B, b, W, X, Y, Z, R1, R2, and R3 have the meanings given in claim 1, pharmaceutical compositions these compounds, and methods of preventing or treating metabolic disorders and/or eating disorders, particularly obesity, bulimia, anorexia, hyperphagia, and diabetes using these compounds.
    Type: Application
    Filed: December 23, 2004
    Publication date: December 1, 2005
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Thorsten Lehmann-Lintz, Ralf Lotz, Philipp Lustenberger, Stephan Mueller, Gerald Roth, Klaus Rudolf, Marcus Schindler, Dirk Stenkamp, Leo Thomas
  • Alkyne compounds with MCH antagonistic activity and medicaments comprising these compounds
    Publication number: 20050267120
    Abstract: Alkyne compounds of formula I wherein A, B, W, X, Y, Z, R1, and R2 have the meanings given herein, which have MCH-receptor antagonistic activity and are useful for preparing pharmaceutical compositions for the treatment of metabolic disorders and/or eating disorders, particularly obesity and diabetes.
    Type: Application
    Filed: April 13, 2005
    Publication date: December 1, 2005
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Dirk Stenkamp, Stephan Mueller, Philipp Lustenberger, Thorsten Lehmann-Lintz, Gerald Roth, Klaus Rudolf, Marcus Schindler, Leo Thomas, Ralf Lotz
  • Beta-ketoamide compounds with MCH antagonistic activity
    Publication number: 20050245500
    Abstract: Compounds of formula I wherein the groups and residues A, B, b, X, Y, Z, R1, R2, R3, R5a and R5b have the meanings given in claim 1. The invention further relates to pharmaceutical compositions containing at least one amide according to the invention. As a result of their MCH-receptor antagonistic activity the pharmaceutical compositions according to the invention are suitable for the treatment of metabolic disorders and/or eating disorders, particularly obesity, bulimia, anorexia, hyperphagia, and diabetes.
    Type: Application
    Filed: March 3, 2005
    Publication date: November 3, 2005
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Gerald Roth, Philipp Lustenberger, Dirk Stenkamp, Stephan Mueller, Thorsten Lehmann-Lintz, Marcus Schindler, Leo Thomas, Ralf Lotz, Marco Santagostino
  • Alkyne compounds with MCH antagonistic activity and medicaments comprising these compounds
    Publication number: 20050245529
    Abstract: Alkyne compounds of formula I wherein A, B, W, X, Y, Z, R1, and R2 have the meanings given herein, which have MCH-receptor antagonistic activity and are useful for preparing pharmaceutical compositions for the treatment of metabolic disorders and/or eating disorders, particularly obesity and diabetes.
    Type: Application
    Filed: April 13, 2005
    Publication date: November 3, 2005
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Dirk Stenkamp, Stephan Mueller, Philipp Lustenberger, Thorsten Lehmann-Lintz, Gerald Roth, Klaus Rudolf, Marcus Schindler, Leo Thomas, Ralf Lotz
  • Alkyne compounds with MCH antagonistic activity and medicaments comprising these compounds
    Publication number: 20050239826
    Abstract: The present invention relates to alkyne compounds of general formula I wherein the groups and radicals A, B, W, X, Y, Z, R1 and R2 have the meanings given in claim 1. Moreover the invention relates to pharmaceutical compositions containing at least one alkyne according to the invention. By virtue of their MCH-receptor antagonistic activity the pharmaceutical compositions according to the invention are suitable for the treatment of metabolic disorders and/or eating disorders, particularly obesity and diabetes.
    Type: Application
    Filed: April 13, 2005
    Publication date: October 27, 2005
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Dirk Stenkamp, Stephan Mueller, Philipp Lustenberger, Thorsten Lehmann-Lintz, Gerald Roth, Klaus Rudolf, Marcus Schindler, Leo Thomas, Ralf Lotz
  • Alkyne compounds with MCH antagonistic activity and medicaments comprising these compounds
    Publication number: 20050234101
    Abstract: Alkyne compounds having MCH-receptor antagonistic activity, which are useful for preparing pharmaceutical compositions for the treatment of metabolic disorders and/or eating disorders, particularly obesity and diabetes.
    Type: Application
    Filed: April 13, 2005
    Publication date: October 20, 2005
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Dirk Stenkamp, Stephan Mueller, Philipp Lustenberger, Thorsten Lehmann-Lintz, Gerald Roth, Klaus Rudolf, Marcus Schindler, Leo Thomas, Ralf Lotz
  • Indolinones substituted by heterocycles, the preparation thereof and their use as medicaments
    Publication number: 20050054710
    Abstract: The present invention relates to heterocyclically substituted indolinones of general formula wherein R1 to R5 and X are defined as in claim 1, the tautomers, the diastereomers, the enantiomers, the mixtures thereof, the prodrugs thereof and the salts thereof, particularly the physiologically acceptable salts thereof which have valuable pharmacological properties, in particular an inhibiting effect on various receptor tyrosine kinases and cyclin/CDK complexes and on the proliferation of endothelial cells and various tumour cells, pharmaceutical compositions containing these compounds, their use and processes for preparing them.
    Type: Application
    Filed: September 5, 2003
    Publication date: March 10, 2005
    Applicant: Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventors: Joerg Kley, Frank Hilberg, Armin Heckel, Gerald Roth, Thorsten Lehmann-Lintz, Ralf Lotz, Ulrike Tontsch-Grunt, Jacobus Van Meel
  • Amide compounds having MCH-antagonistic activity and medicaments comprising these compounds
    Publication number: 20040152742
    Abstract: The present invention relates to amide compounds of general formula I 1
    Type: Application
    Filed: October 31, 2003
    Publication date: August 5, 2004
    Applicant: Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventors: Dirk Stenkamp, Stephan Georg Mueller, Gerald Juergen Roth, Philipp Lustenberger, Klaus Rudolf, Thorsten Lehmann-Lintz, Kirsten Arndt, Ralf Lotz, Martin Lenter, Heike-Andrea Wieland
  • Xanthine derivatives, the preparation thereof and their use as pharmaceutical compositions
    Publication number: 20040087587
    Abstract: The present invention relates to substituted xanthines of general formula 1
    Type: Application
    Filed: October 24, 2003
    Publication date: May 6, 2004
    Applicant: Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventors: Frank Himmelsbach, Michael Mark, Matthias Eckhardt, Elke Langkopf, Roland Maier, Ralf Lotz
  • Xanthine derivatives, the preparation thereof and their use as pharmaceutical compositions
    Publication number: 20020198205
    Abstract: The present invention relates to substituted xanthines of general formula 1
    Type: Application
    Filed: February 22, 2002
    Publication date: December 26, 2002
    Inventors: Frank Himmelsbach, Michael Mark, Matthias Eckhardt, Elke Langkopf, Roland Maier, Ralf Lotz