Patents by Inventor Ralf-Michael Schmidt

Ralf-Michael Schmidt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20110113494
    Abstract: The present invention relates to serine hydroxymethyltransferase (E.C. 2.1.2.1) as novel target for herbicides, and to nucleic acid sequences encoding a polypeptide with the biological activity of a serine hydroxymethyltransferase, which, when not present, bring about growth retardation symptoms and chlorotic leaves, comprising the nucleic acid sequence SEQ ID No:3, and functional equivalents of the abovementioned nucleic acid sequence or the nucleic acid sequence SEQ ID NO:7 and functional equivalents of the abovementioned nucleic acid sequence. Moreover, the present invention relates to the use of the abovementioned nucleic acid sequences, of functional analogs of the SEQ ID NO:3 or SEQ ID NO:7 or of polypeptides encoded by one of the abovementioned nucleic acid sequences in a method for identifying herbicidally active compounds which inhibit serine hydroxymethyltransferases, and to the use of these compounds which have been identified by the method as herbicides.
    Type: Application
    Filed: December 23, 2009
    Publication date: May 12, 2011
    Applicant: BASF Aktiengesellschaft
    Inventors: Uwe Sonnewald, Frederik Börnke, Kirsten Deist, Marc Stitt Nigel, Wolfgang Lein, Thomas Ehrhardt, Andreas Reindl, Ralf-Michael Schmidt, Annette Freund
  • Patent number: 7799971
    Abstract: The present invention relates to a method for the production of transgenic plants and/or plant cells, respectively, with increased pathogen resistance, characterized in that a DNA sequence, which encodes a protein with the activity of a peroxidase, is inserted into the plant and expressed therein. The invention at hand also relates to the use of nucleic acids encoding a peroxidase for the production of transgenic plants, or plant cells, respectively, with increased pathogen resistance. Further, the invention at hand relates to nucleic acid sequences encoding a peroxidase of barley.
    Type: Grant
    Filed: June 14, 2005
    Date of Patent: September 21, 2010
    Assignee: BASF Plant Sciences GmbH
    Inventors: Markus Frank, Ralf-Michael Schmidt, Sandra Stauder
  • Patent number: 7662603
    Abstract: The present invention relates to serine hydroxymethyltransferase (E.C. 2.1.2.1) as novel target for herbicides, and to nucleic acid sequences encoding a polypeptide with the biological activity of a serine hydroxymethyltransferase, which, when not present, bring about growth retardation symptoms and chlorotic leaves, comprising the nucleic acid sequence SEQ ID No:3, and functional equivalents of the abovementioned nucleic acid sequence or the nucleic acid sequence SEQ ID NO:7 and functional equivalents of the abovementioned nucleic acid sequence. Moreover, the present invention relates to the use of the abovementioned nucleic acid sequences, of functional analogs of the SEQ ID NO:3 or SEQ ID NO:7 or of polypeptides encoded by one of the abovementioned nucleic acid sequences in a method for identifying herbicidally active compounds which inhibit serine hydroxymethyltransferases, and to the use of these compounds which have been identified by the method as herbicides.
    Type: Grant
    Filed: December 4, 2007
    Date of Patent: February 16, 2010
    Assignee: BASF Aktiengesellschaft
    Inventors: Uwe Sonnewald, Frederik Boernke, Kirsten Deist, Marc Stitt Nigel, Wolfgang Lein, Thomas Ehrhardt, Andreas Reindl, Ralf-Michael Schmidt, Annette Freund
  • Publication number: 20080282425
    Abstract: The present invention relates to a method for the production of transgenic plants and/or plant cells, respectively, with increased pathogen resistance, characterized in that a DNA sequence, which encodes a protein with the activity of a peroxidase, is inserted into the plant and expressed therein. The invention at hand also relates to the use of nucleic acids encoding a peroxidase for the production of transgenic plants, or plant cells, respectively, with increased pathogen resistance. Further, the invention at hand relates to nucleic acid sequences encoding a peroxidase of barley.
    Type: Application
    Filed: June 14, 2005
    Publication date: November 13, 2008
    Inventors: Markus Frank, Ralf-Michael Schmidt, Sandra Stauder
  • Publication number: 20080155716
    Abstract: The present invention relates to serine hydroxymethyltransferase (E.C. 2.1.2.1) as novel target for herbicides, and to nucleic acid sequences encoding a polypeptide with the biological activity of a serine hydroxymethyltransferase, which, when not present, bring about growth retardation symptoms and chlorotic leaves, comprising the nucleic acid sequence SEQ ID No:3, and functional equivalents of the abovementioned nucleic acid sequence or the nucleic acid sequence SEQ ID NO:7 and functional equivalents of the abovementioned nucleic acid sequence. Moreover, the present invention relates to the use of the abovementioned nucleic acid sequences, of functional analogs of the SEQ ID NO:3 or SEQ ID NO:7 or of polypeptides encoded by one of the abovementioned nucleic acid sequences in a method for identifying herbicidally active compounds which inhibit serine hydroxymethyltransferases, and to the use of these compounds which have been identified by the method as herbicides.
    Type: Application
    Filed: December 4, 2007
    Publication date: June 26, 2008
    Applicant: BASF Aktiengesellschaft
    Inventors: Uwe SONNEWALD, Frederik BORNKE, Kirsten DEIST, Marc Stitt NIGEL, Wolfgang LEIN, Thomas EHRHARDT, Andreas REINDL, Ralf-Michael SCHMIDT, Annette FREUND
  • Publication number: 20080120740
    Abstract: A process for increasing the resistance against mesophyllic cell-penetrating pathogens in a plant, or an organ, tissue or a cell thereof, wherein the callose synthase activity in the plant or an organ, tissue or a cell thereof is reduced in comparison to control plants.
    Type: Application
    Filed: May 6, 2005
    Publication date: May 22, 2008
    Applicant: BASF Plant Science GmbH
    Inventors: Markus Frank, Ralf-Michael Schmidt
  • Patent number: 7319013
    Abstract: The present invention relates to serine hydroxymethyltransferase (E.C. 2.1.2.1) as novel target for herbicides, and to nucleic acid sequences encoding a polypeptide with the biological activity of a serine hydroxymethyltransferase, which, when not present, bring about growth retardation symptoms and chlorotic leaves, comprising the nucleic acid sequence SEQ ID No:3, and functional equivalents of the abovementioned nucleic acid sequence or the nucleic acid sequence SEQ ID NO:7 and functional equivalents of the abovementioned nucleic acid sequence. Moreover, the present invention relates to the use of the abovementioned nucleic acid sequences, of functional analogs of the SEQ ID NO:3 or SEQ ID NO:7 or of polypeptides encoded by one of the abovementioned nucleic acid sequences in a method for identifying herbicidally active compounds which inhibit serine hydroxymethyltransferases, and to the use of these compounds which have been identified by the method as herbicides.
    Type: Grant
    Filed: March 13, 2003
    Date of Patent: January 15, 2008
    Assignee: BASF Aktiengesellschaft
    Inventors: Uwe Sonnewald, Frederik Börnke, Kirsten Deist, Marc Stitt Nigel, Wolfgang Lein, Thomas Ehrhardt, Andreas Reindl, Ralf-Michael Schmidt, Annette Freund
  • Publication number: 20070113300
    Abstract: The present invention relates to Clp-protease, which, when absent, brings about reduced growth and chlorotic leaves as target for herbicides. For this purpose, novel nucleic acid sequences encompassing SEQ ID NO:3, SEQ ID NO:11 and SEQ ID NO: 17 and functional equivalents of SEQ ID NO:3, SEQ ID NO:11 and SEQ ID NO: 17 are provided. Moreover, the present invention relates to the use of Clp-protease in a method for identifying compounds with herbicidal or growth-regulatory activity, and to the use of the compounds identified by this method as herbicides or growth regulators.
    Type: Application
    Filed: November 30, 2004
    Publication date: May 17, 2007
    Applicant: BASF Aktiengesellschaft
    Inventors: Thomas Ehrhardt, Andreas Reindl, Annette Freund, Ralf-Michael Schmidt, Uwe Sonnewald, Marc Nigel, Wolfgang Lein, Frederik Bornke, Kirsten Deist
  • Publication number: 20070042451
    Abstract: The invention relates to the use of glycine decarboxylase complex, which is used as a target for herbicides in the absence of growth retardations and chlorotic leaves. Novel nucleic acid sequences comprising SEQ ID NO:1 and functional equivalents of SEQ ID NO:1 are thus disclosed. The invention also relates to the use of glycine decarboxylase complex and the functional equivalents thereof in a method for identifying compounds having a herbicidal or growth-regulatory effect, in addition to the use of said compounds identified via said method as herbicides or growth regulators.
    Type: Application
    Filed: October 27, 2004
    Publication date: February 22, 2007
    Applicant: BASF Aktiengesellschaft
    Inventors: Thomas Ehrhardt, Andreas Reindl, Annette Freund, Ralf-Michael Schmidt, Uwe Sonnewald, Marc Nigel, Wolfgang Lein, Frederik Bornke, Kirsten Deist
  • Publication number: 20070003934
    Abstract: The present invention relates to the use of 2-methyl-6-solanylbenzoquinone methyltransferase which, when absent, brings about retarded growth and chlorotic leaves, as target for herbicides. In this context, there are provided novel nucleic acid sequences comprising SEQ ID NO:5 and SEQ ID NO:7 and corresponding functional equivalents. Moreover, the present invention relates to the use of 2-methyl-6-solanylbenzoquinone methyltransferase and its functional equivalents in a method for identifying herbicidal or growth-regulatory compounds, and to the use of the compounds identifed via the method as herbicides or growth regulators.
    Type: Application
    Filed: November 30, 2004
    Publication date: January 4, 2007
    Applicant: BASF AKIENGESELLSCHAFT
    Inventors: Thomas Ehrhardt, Andreas Reindl, Annette Freund, Ralf-Michael Schmidt, Uwe Sonnewald, Marc Nigel, Wolfgang Lein, Frederik Bornke
  • Publication number: 20060160223
    Abstract: The invention relates to novel plasmid vectors for transformation of filamentous fungi and to a method of modifiying the genome of filamentous fungi based on these vectors. The invention furthermore relates to the modification of a specific gene via the process of homologous recombination, to recombinant expression of foreign genes in filamentous fungi and to new selection markers for detecting succesfull transfer of the target gene in filamentous fungi.
    Type: Application
    Filed: July 2, 2003
    Publication date: July 20, 2006
    Inventors: Thierry Lacour, Jan Rether, Annette Freund, Ralf-Michael Schmidt, Wilhelm Schafer, Frank Maier, Sascha Malz
  • Publication number: 20060068393
    Abstract: The present invention relates to the provision of mevalonate kinase as target for fungicides, to the provision of novel nucleic acid sequences, of functional equivalents of the abovementioned nucleic acid sequences and to the use of the gene products of the abovementioned nucleic acid sequences as novel targets for fungicides. Moreover, the present invention relates to methods for identifying fungicides which inhibit a polypeptide with the biological activity of a mevalonate kinase and to the use of these compounds identified via the abovementioned method as fungicides.
    Type: Application
    Filed: January 28, 2004
    Publication date: March 30, 2006
    Inventors: Thierry Lacour, Jan Rether, Annette Freund, Ralf-Michael Schmidt
  • Publication number: 20060058190
    Abstract: The present invention relates to malate dehydrogenase, which, when absent, brings about reduced growth and chlorotic leaves and is encoded by the nucleic acid sequence SEQ ID NO:2 or by a functional equivalent of this nucleic acid sequence, as target for herbicides. For this purpose, novel nucleic acid sequences encompassing SEQ ID NO:2 and functional equivalents of SEQ ID NO:2 are provided. Moreover, the present invention relates to the use of the abovementioned malate dehydrogenase and its functional equivalents in a method for identifying compounds with herbicidal or growth-regulatory activity, and to the use of the compounds identified by this method as herbicides or growth regulators.
    Type: Application
    Filed: December 17, 2003
    Publication date: March 16, 2006
    Inventors: Thomas Ehrhardt, Andreas Reindl, Annette Freund, Ralf-Michael Schmidt, Kirsten Deist, Uwe Sonnewald, Marc Nigel, Wolfgang Lein, Frederik Bornke
  • Publication number: 20050142553
    Abstract: The present invention relates to serine hydroxymethyltransferase (E.C. 2.1.2.1) as novel target for herbicides, and to nucleic acid sequences encoding a polypeptide with the biological activity of a serine hydroxymethyltransferase, which, when not present, bring about growth retardation symptoms and chlorotic leaves, comprising the nucleic acid sequence SEQ ID No:3, and functional equivalents of the abovementioned nucleic acid sequence or the nucleic acid sequence SEQ ID NO:7 and functional equivalents of the abovementioned nucleic acid sequence. Moreover, the present invention relates to the use of the abovementioned nucleic acid sequences, of functional analogs of the SEQ ID NO:3 or SEQ ID NO:7 or of polypeptides encoded by one of the abovementioned nucleic acid sequences in a method for identifying herbicidally active compounds which inhibit serine hydroxymethyltransferases, and to the use of these compounds which have been identified by the method as herbicides.
    Type: Application
    Filed: March 13, 2003
    Publication date: June 30, 2005
    Inventors: Uwe Sonnewald, Frederik Bornke, Kirsten Deist, Marc Nigel, Wolfgang Lein, Thomas Ehrhardt, Andreas Reindl, Ralf-Michael Schmidt, Annette Freund
  • Patent number: 6610840
    Abstract: The present invention relates to a method of isolating a promoter, which causes, in plants, permanent Mesophyll-specific expression of an operably linked encoding nucleotide sequence, for example a sequence which imparts resistance or an increase in the photosynthetic performance.
    Type: Grant
    Filed: March 7, 2001
    Date of Patent: August 26, 2003
    Assignee: BASF Aktiengesellschaft
    Inventors: Uwe Sonnewald, Marcus Ebneth, Ralf-Michael Schmidt
  • Publication number: 20030157592
    Abstract: Isolated nucleic acid molecules, designated TCMRP nucleic acid molecules, which encode novel TCMRPs from e.g. Phycomitrella patens are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing TCMRP nucleic acid molecules, and host cells into which the expression vectors have been introduced. The invention still further provides isolated TCMRPs, mutated TCMRPs, fusion proteins, antigenic peptides and methods for the improvement of production of a desired compound from transformed cells, organisms or plants based on genetic engineering of TCMRP genes in these organisms.
    Type: Application
    Filed: June 13, 2002
    Publication date: August 21, 2003
    Inventors: Jens Lerchl, Andreas Renz, Thomas Ehrhardt, Andreas Reindl, Petra Cirpus, Friedrich Bischoff, Markus Frank, Annette Freund, Elke Duwenig, Ralf-Michael Schmidt, Ralf Reski, Ralf Badur
  • Publication number: 20030024003
    Abstract: Isolated nucleic acid molecules, designated GDRP nucleic acid molecules, which encode novel GDRPs from Physcomitrella patens are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing GDRP nucleic acid molecules, and host cells and organisms into which the expression vectors have been introduced. The invention still further provides isolated GDRPs, mutated GDRPs, fusion proteins, antigenic peptides and methods for the improvement of production of a desired compound from transformed cells based on genetic engineering of GDRP genes in this organism.
    Type: Application
    Filed: January 25, 2001
    Publication date: January 30, 2003
    Inventors: Markus Frank, Andreas Reindl, Ralf-Michael Schmidt, Annette Freund, Thomas Ehrhardt, Friedrich Bischoff, Andreas Renz, Elke Duwenig, Petra Cirpus, Jens Lerchl, Ralf Reski
  • Patent number: 6472587
    Abstract: Process for production of herbicide-tolerant plants by expressing an exogenous herbicide-binding polypeptide in plants or plant organs. The invention furthermore relates to the use of the corresponding nucleic acids which encode a polypeptide, an antibody or parts of an antibody with herbicide-binding properties in transgenic plants, and the thus transformed plant itself.
    Type: Grant
    Filed: September 21, 1999
    Date of Patent: October 29, 2002
    Assignee: BASF Aktiengesellschaft
    Inventors: Jens Lerchl, Achim Möller, Ralf-Michael Schmidt, Helmut Schiffer, Udo Rabe, Udo Conrad
  • Publication number: 20020142422
    Abstract: Isolated nucleic acid molecules, designated MP protein nucleic acid molecules, which encode novel MP proteins from e.g. Phycomitrella patens are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing MP protein nucleic acid molecules, and host cells into which the expression vectors have been introduced. The invention still further provides isolated MP proteins, mutated MP proteins, fusion proteins, antigenic peptides and methods for the improvement of production of a desired compound from transformed cells, organisms or plants based on genetic engineering of MP protein genes in these organisms.
    Type: Application
    Filed: December 12, 2000
    Publication date: October 3, 2002
    Inventors: Jens Lerchl, Andreas Renz, Thomas Ehrhardt, Andreas Reindl, Petra Cirpus, Friedrich Bischoff, Markus Frank, Annette Freund, Elke Duwenig, Ralf-Michael Schmidt, Ralf Reski
  • Publication number: 20020120955
    Abstract: Leaf-specific expression of genes in transgenic plants The present invention relates to promoters which cause, in plants, permanent leaf-specific expression of an encoding nucleotide sequence under the control of said promoters, for example a sequence which imparts resistance or an increase in the photosynthetic performance.
    Type: Application
    Filed: March 7, 2001
    Publication date: August 29, 2002
    Inventors: Uwe Sonnewald, Marcus Ebneth, Ralf-Michael Schmidt