Patents by Inventor Ralf Proplesch

Ralf Proplesch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FLAVOR AND FRAGRANCE FORMULATION (VII)
    Publication number: 20160340285
    Abstract: The present invention relates to the use of a specific organic compound as flavor and fragrance material. Furthermore the invention relates to flavor and fragrance formulations comprising such a specific organic compound of formula (I).
    Type: Application
    Filed: January 30, 2015
    Publication date: November 24, 2016
    Inventors: Ralf PROPLESCH, Johannes TSCHUMI, Raphael BEUMER
  • Process for the manufacture of substituted 2-cyano cinnamic esters
    Patent number: 8110702
    Abstract: The invention relates to an improved process for the manufacture of substitute 2-cyanocinnamic esters. This novel economical process provides products in high purity and yields.
    Type: Grant
    Filed: September 24, 2010
    Date of Patent: February 7, 2012
    Assignee: DSM IP Assets B.V.
    Inventors: Jing Huang, Shuping Jing, Reinhard Karge, Ralf Proplesch
  • Process for the manufacture of substituted 2-cyano cinnamic esters
    Patent number: 7985870
    Abstract: The invention relates to an improved process for the manufacture of substituted 2-cyanocinnamic esters. This novel economical process provides products in high purity and yields.
    Type: Grant
    Filed: January 18, 2008
    Date of Patent: July 26, 2011
    Assignee: DSM IP Assets B.V.
    Inventors: Jing Huang, Shuping Jing, Reinhard Karge, Ralf Proplesch
  • PROCESS FOR THE MANUFACTURE OF SUBSTITUTED 2-CYANO CINNAMIC ESTERS
    Publication number: 20110014140
    Abstract: The invention relates to an improved process for the manufacture of substitute 2-cyanocinnamic esters. This novel economical process provides products in high purity and yields.
    Type: Application
    Filed: September 24, 2010
    Publication date: January 20, 2011
    Inventors: Jing HUANG, Shuping Jing, Reinhard Karge, Ralf Proplesch
  • PROCESS FOR THE MANUFACTURE OF SUBSTITUTED 2-CYANO CINNAMIC ESTERS
    Publication number: 20100048937
    Abstract: The invention relates to an improved process for the manufacture of substituted 2-cyanocinnamic esters. This novel economical process provides products in high purity and yields.
    Type: Application
    Filed: January 18, 2008
    Publication date: February 25, 2010
    Inventors: Jing Huang, Shuping Jing, Reinhard Karge, Ralf Proplesch
  • Novel Composition Comprising Ligustilide and Process For Their Manufacture
    Publication number: 20080152730
    Abstract: Novel purified extracts from Ligusticum species are obtained by submitting crude extracts from Ligusticum species, particularly from Ligusticum wallichii (chuanxiong) containing less than 50 wt.-% of ligustilide to rectification under specific conditions.
    Type: Application
    Filed: January 26, 2006
    Publication date: June 26, 2008
    Inventors: Ralf Proplesch, Christoph Riegger, Werner Simon, Swen Wolfram
  • Process for preparing 1-(6-methylpyridin-3-yl)-2-[4- (methylsulphonyl)phenyl]ethanone
    Patent number: 7355048
    Abstract: A four-step process for preparing 1-(6-methylpyridin-3-yl)-2-[4-(methylsulfonyl)phenyl]ethanone of the formula: starting from 2-methyl-5-ethylpyridine. 1-(6-Methylpyridin-3yl)-2-[4-(methylsulfonyl)phenyl]ethanone is an intermediate for preparing inhibitors.
    Type: Grant
    Filed: January 6, 2005
    Date of Patent: April 8, 2008
    Assignees: Lonza Ltd., Merck & Co. Inc.
    Inventors: David Kuo, James E. Leresche, Ralf Proplesch, Jean-Paul Roduit, Yves Bessard, Erich Armbruster
  • 1-(6-methylpyridine-3-yl)-2-[4-(methylsulphonyl) phenyl] ethanone and method for its preparation
    Patent number: 7141673
    Abstract: A starting product for the preparation of COX-2 inhibitors, notably the compound 1-(6-methylpyridine-3-yl)-2-[(4-(methylsulfonyl)phenyl]ethanone of the formula (I): A method for making the compound.
    Type: Grant
    Filed: January 13, 2000
    Date of Patent: November 28, 2006
    Assignee: Lonza AG
    Inventors: Erich Armbruster, Yves Bessard, David Kuo, James E. Leresche, Ralf Proplesch, Jean-Paul Roduit
  • Process for preparing 1-( 6-methylpyridin-3-yl)-2-[4- (methylsulfonyl)phenyl]ethanone
    Publication number: 20050159458
    Abstract: A four-step process for preparing 1-(6-methylpyridin-3-yl)-2-[4-(methylsulfonyl)phenyl]ethanone of the formula: starting from 2-methyl-5-ethylpyridine. 1-(6-Methylpyridin-3yl)-2-[4-(methylsulfonyl)phenyl]ethanone is an intermediate for preparing inhibitors.
    Type: Application
    Filed: January 6, 2005
    Publication date: July 21, 2005
    Inventors: David Kuo, James Leresche, Ralf Proplesch, Jean-Paul Roduit, Yves Bessard, Erich Armbruster