Patents by Inventor Ralf Reski

Ralf Reski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10174334
    Abstract: The field of the invention relates to a method for the production of a recombinant protein in a plant-based system comprising the steps of providing a plant-based system comprising a modulation for a plant endogenous prolyl-4-hydroxylase gene, delivering a gene encoding the recombinant protein into the plant-based system, and cultivating the plant-based system for the expression of the gene encoding the recombinant protein. The field of the invention further relates to a recombinant protein, which has been produced in a plant-based system. A plant-based system and use of the recombinant protein are also provided.
    Type: Grant
    Filed: May 5, 2014
    Date of Patent: January 8, 2019
    Assignees: ALBERT-LUDWIGS-UNIVERSITAET FREIBURG, UNIVERSITAET FUER BODENKULTUR WIEN
    Inventors: Ralf Reski, Juliana Parsons, Friedrich Altmann, Manuela Graf, Eva Decker, Johannes Stadlmann
  • Patent number: 9611441
    Abstract: The present invention relates to an improved process for the preparation of unsaturated fatty acids and to a process for the preparation of triglycerides with an increased content of unsaturated fatty acids. The invention relates to the generation of transgenic microorganism, with an increased content of fatty acids, oils or lipids with ?6 double bonds owing to the expression of a moss ?6-desaturase. The invention furthermore relates to transgenic organisms comprising a ?6-desaturase gene, and to the use of unsaturated fatty acids ort of the triglycerides with an increased content if unsaturated fatty acids prepared in the process.
    Type: Grant
    Filed: May 2, 2014
    Date of Patent: April 4, 2017
    Assignee: BASF Plant Science GmbH
    Inventors: Ernst Heinz, Thomas Girke, Jodi Scheffler, Oswaldo Da Costa e Silva, Hermann Schmidt, Ulrich Zähringer, Ralf Reski
  • Publication number: 20170066994
    Abstract: The present invention relates to an improved process for the preparation of unsaturated fatty acids and to a process for the preparation of triglycerides with an increased content of unsaturated fatty acids. The invention relates to the generation of transgenic microorganism, with an increased content of fatty acids, oils or lipids with ?6 double bonds owing to the expression of a moss ?6-desaturase. The invention furthermore relates to transgenic organisms comprising a ?6-desaturase gene, and to the use of unsaturated fatty acids ort of the triglycerides with an increased content if unsaturated fatty acids prepared in the process.
    Type: Application
    Filed: May 2, 2014
    Publication date: March 9, 2017
    Applicant: BASF Plant Science GmbH
    Inventors: Ernst Heinz, Thomas Girke, Jodi Scheffler, Oswaldo Da Costa e Silva, Hermann Schmidt, Ulrich Zähringer, Ralf Reski
  • Publication number: 20160208275
    Abstract: The field of the invention relates to a method for the production of a recombinant protein in a plant-based system comprising the steps of providing a plant-based system comprising a modulation for a plant endogenous prolyl-4-hydroxylase gene, delivering a gene encoding the recombinant protein into the plant-based system, and cultivating the plant-based system for the expression of the gene encoding the recombinant protein. The field of the invention further relates to a recombinant protein, which has been produced in a plant-based system. A plant-based system and use of the recombinant protein are also provided.
    Type: Application
    Filed: May 5, 2014
    Publication date: July 21, 2016
    Inventors: Ralf Reski, Juliana Parsons, Friedrich Altmann, Manuela Graf, Eva Decker, Johannes Stadlmann
  • Patent number: 8835715
    Abstract: The present invention relates to an improved process for the preparation of unsaturated fatty acids and to a process for the preparation of triglycerides with an increased content of unsaturated fatty acids. The invention relates to the generation of transgenic organism, preferably of a transgenic plant or of a transgenic microorganism, with an increased content of fatty acids, oils or lipids with ?6 double bonds owing to the expression of a moss ?-6-desaturase [sic]. The invention furthermore relates to transgenic organisms comprising a ?6-desaturase gene, and to the use of the unsaturated fatty acids or of the triglycerides with an increased content of unsaturated fatty acids prepared in the process.
    Type: Grant
    Filed: July 4, 2000
    Date of Patent: September 16, 2014
    Assignee: BASF Plant Science GmbH
    Inventors: Ernst Heinz, Thomas Girke, Jodi Scheffler, Oswaldo Da Costa E Silva, Hermann Schmidt, Ulrich Zähringer, Ralf Reski
  • Publication number: 20140235733
    Abstract: The present invention relates to an improved process for the preparation of unsaturated fatty acids and to a process for the preparation of triglycerides with an increased content of unsaturated fatty acids. The invention relates to the generation of transgenic microorganism, with an increased content of fatty acids, oils or lipids with ?6 double bonds owing to the expression of a moss ?6-desaturase. The invention furthermore relates to transgenic organisms comprising a ?6-desaturase gene, and to the use of unsaturated fatty acids ort of the triglycerides with an increased content if unsaturated fatty acids prepared in the process.
    Type: Application
    Filed: May 2, 2014
    Publication date: August 21, 2014
    Applicant: BASF Plant Science GmbH
    Inventors: Ernst Heinz, Thomas Girke, Jodi Scheffler, Oswaldo Da Costa e Silva, Hermann Schmidt, Ulrich Zähringer, Ralf Reski
  • Patent number: 7781197
    Abstract: Bryophyte plants and bryophyte plant cells comprising dysfunctional fucT and xylT genes and an introduced glycosyltransferase gene, methods for the production of glycosylated proteins therewith, vectors and uses thereof.
    Type: Grant
    Filed: December 18, 2003
    Date of Patent: August 24, 2010
    Assignee: greenovation Biotech GmbH
    Inventors: Ralf Reski, Gilbert Gorr, Eva Decker, Christian Stemmer, Otmar Lienhart, Anna Koprivova
  • Publication number: 20100050292
    Abstract: The invention discloses DNA molecules encoding galactosyltransferases, recombinant host cells, tissues or organisms comprising dysfunctional galactosyltransferase gene(s), recombinant host cells, tissues or organisms comprising an introduced functional galactosyltransferase gene, methods for the production of proteins therewith, methods for the production of galactosyltransferase and vectors and uses thereof.
    Type: Application
    Filed: September 28, 2007
    Publication date: February 25, 2010
    Applicant: GREENOVATION BIOTECH GMBH
    Inventors: Heike Launhardt, Christian Stemmer, Wolfgang Jost, Gilbert Gorr, Ralf Reski, Stefan Rensing
  • Publication number: 20080141387
    Abstract: Bryophyte plants and bryophyte plant cells comprising dysfunctional fucT and xylT genes and an introduced glycosyl transferase gene, methods for the production of glycosylated proteins therewith, vectors and uses thereof.
    Type: Application
    Filed: December 18, 2003
    Publication date: June 12, 2008
    Applicant: Greenovation Biotech GmbH
    Inventors: Ralf Reski, Gilbert Gorr, Eva Decker, Christian Stemmer, Otmar Lienhart, Anna Koprivova
  • Publication number: 20060058189
    Abstract: The present invention relates to nucleic acids containing a nucleotide sequence encoding a polypeptide as a target for herbicidal compounds, to said polypeptides or biologically active derivatives thereof, and to a mehotd for developing herbicidal compounds using test systems containing said polypeptides.
    Type: Application
    Filed: December 12, 2003
    Publication date: March 16, 2006
    Inventors: Ralf Reski, Eva Decker, Justine Kiessling
  • Publication number: 20060051773
    Abstract: The invention relates to a method for the mutagenesis of eukaryotic nucleotide sequences, preferably from plants, algae and/or fungi and a method for the production of genetically modified eukaryotic cells. The subject of the invention is the genetically altered nucleotide sequences of the type disclosed, vectors containing such nucleotide sequences, as well as genetically altered eukaryotic cells, tissue and/or parts of plants, algae and/or fungi and/or regenerated whole plants and the use thereof.
    Type: Application
    Filed: November 29, 2004
    Publication date: March 9, 2006
    Inventors: Bodo Rak, Ralf Reski, Susanne Zimmermann, Marie-Christine Guitton, Elke Duwenig, Annette Freund
  • Patent number: 6824983
    Abstract: The invention relates to a method for the mutagenesis of eucaryotic nucleotide sequences, preferably from plants, algae and/or fungi and a method for the production of genetically modified eucaryotic cells. The subject of the invention is the genetically altered nucleotide sequences of the type disclosed, vectors containing such nucleotide sequences, as well as genetically altered eucaryotic cells, tissue and/or parts of plants, algea and/or fungi and/or regenerated whole plants and the use thereof.
    Type: Grant
    Filed: May 17, 2002
    Date of Patent: November 30, 2004
    Assignees: BASF Plant Science GmbH, Albert-Ludwigs-Universitat Freiburg
    Inventors: Bodo Rak, Ralf Reski, Susanne Zimmermann, Marie-Christine Guitton, Elke Duwenig, Annette Freund
  • Publication number: 20030157592
    Abstract: Isolated nucleic acid molecules, designated TCMRP nucleic acid molecules, which encode novel TCMRPs from e.g. Phycomitrella patens are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing TCMRP nucleic acid molecules, and host cells into which the expression vectors have been introduced. The invention still further provides isolated TCMRPs, mutated TCMRPs, fusion proteins, antigenic peptides and methods for the improvement of production of a desired compound from transformed cells, organisms or plants based on genetic engineering of TCMRP genes in these organisms.
    Type: Application
    Filed: June 13, 2002
    Publication date: August 21, 2003
    Inventors: Jens Lerchl, Andreas Renz, Thomas Ehrhardt, Andreas Reindl, Petra Cirpus, Friedrich Bischoff, Markus Frank, Annette Freund, Elke Duwenig, Ralf-Michael Schmidt, Ralf Reski, Ralf Badur
  • Publication number: 20030024003
    Abstract: Isolated nucleic acid molecules, designated GDRP nucleic acid molecules, which encode novel GDRPs from Physcomitrella patens are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing GDRP nucleic acid molecules, and host cells and organisms into which the expression vectors have been introduced. The invention still further provides isolated GDRPs, mutated GDRPs, fusion proteins, antigenic peptides and methods for the improvement of production of a desired compound from transformed cells based on genetic engineering of GDRP genes in this organism.
    Type: Application
    Filed: January 25, 2001
    Publication date: January 30, 2003
    Inventors: Markus Frank, Andreas Reindl, Ralf-Michael Schmidt, Annette Freund, Thomas Ehrhardt, Friedrich Bischoff, Andreas Renz, Elke Duwenig, Petra Cirpus, Jens Lerchl, Ralf Reski
  • Publication number: 20020142422
    Abstract: Isolated nucleic acid molecules, designated MP protein nucleic acid molecules, which encode novel MP proteins from e.g. Phycomitrella patens are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing MP protein nucleic acid molecules, and host cells into which the expression vectors have been introduced. The invention still further provides isolated MP proteins, mutated MP proteins, fusion proteins, antigenic peptides and methods for the improvement of production of a desired compound from transformed cells, organisms or plants based on genetic engineering of MP protein genes in these organisms.
    Type: Application
    Filed: December 12, 2000
    Publication date: October 3, 2002
    Inventors: Jens Lerchl, Andreas Renz, Thomas Ehrhardt, Andreas Reindl, Petra Cirpus, Friedrich Bischoff, Markus Frank, Annette Freund, Elke Duwenig, Ralf-Michael Schmidt, Ralf Reski
  • Publication number: 20020064816
    Abstract: Isolated nucleic acid molecules, designated CMRP nucleic acid molecules, which encode novel CMRPs from Physcomitrella patens are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing CMRP nucleic acid molecules, and host cells and organisms into which the expression vectors have been introduced. The invention still further provides isolated CMRPs, mutated CMRPs, fusion proteins, antigenic peptides and methods for the improvement of production of a desired compound from transformed cells based on genetic engineering of CMRP genes in this organism.
    Type: Application
    Filed: December 13, 2000
    Publication date: May 30, 2002
    Inventors: Jens Lerchl, Andreas Renz, Thomas Ehrhardt, Andreas Reindl, Petra Cirpus, Friedrich Bischoff, Markus Frank, Annette Freund, Elke Duwenig, Ralf-Michael Schmidt, Ralf Reski