Abstract: A method for treating cachecia, liver disease, and other wasting syndromes is provided. The treatment method comprises administering a therapeutically effective amount of a compound that is able to reduce the production, absorption and/or the effect of an endotoxin. Examples of such compounds include, but are not limited to, bile acids; bactericidal/permeability increasing proteins; lipoproteins; antibodies capable of binding to endotoxins; LPS binding protein; activated charcoal, Fuller's earth, attapulgite, kaolin or bentonite or a clay; a drug blocking effectively signaling through toll-like receptors; and calostrum or human, bovine or other mammals.