Ralf Spindler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
Abstract: Disclosed herein are systems and methods for delivering a medical device to a body vessel of a patient. The medical device may be a stent graft, and the delivery assembly may include at least one loop that connects an end stent of the stent graft to a trigger wire of the delivery assembly, thereby providing indirect connection between the device to be delivered and the trigger wire.
Abstract: An aortic stent graft includes a stent with a framework attached to a fabric tube by a plurality of suture ties. The fabric tube includes a plurality of discrete attachment areas that are at least partially surrounded by at least one permeable graft area. The fabric tube is one of a weave and a knit of thermoplastic yarn. Each of the suture ties associated with the discrete attachment areas at least one of penetrates through and encircles a respective one of the discrete attachment areas. The weave or knit of the discrete attachment areas is identical to that of the permeable graft area with an exception that a wall thickness of each of the discrete attachment areas is flattened relative to, and thinner than, a wall thickness of the permeable graft area.
Abstract: A low profiled stent delivery system includes a balloon catheter with a balloon mounted at a first location, and a balloon expandable stent crimped about the balloon catheter at a second location. The stent expands from a crimped state to a less than fully expanded state responsive to movement of an auxiliary expander from a first configuration to a second configuration. An inner diameter of the stent in the less than fully expanded state is greater than an outer diameter of the balloon in a deflated state. After repositioning the balloon within the less than fully expanded state, the balloon is inflated to fully expand the stent.
Abstract: A stent delivery system includes a self expanding stent positioned about a distal support segment of a catheter, which includes a proximal segment. A constraint has a wrapped configuration, which has a hollow elongated shape, and an unwrapped configuration, which is a continuous length of a strip. The stent is in contact with, and held in a compressed state by, the constraint in the wrapped configuration, and the stent is in an expanded state out of contact with the constraint in the unwrapped configuration. The constraint may move from the wrapped configuration toward the unwrapped configuration responsive to tension in a control line connected to one end of the strip.
Abstract: The present embodiments provide a system for controlled release of a portion of a stent. In one example, the system comprises a stent having proximal and distal regions, and a first barb coupled to the stent. A trigger wire restrains a portion of the stent in a delivery state. The system further comprises a barb release wire having proximal and distal regions, and an engagement region disposed therebetween. The distal region of the barb release wire is coupled to the trigger wire, and the engagement region of the barb release wire is disposed around a portion of the first barb to restrain the first barb in the delivery state. In one example, distal retraction of the trigger wire causes a simultaneous distal retraction of the barb release wire.
Abstract: An active implantable medical device comprises an expandable stent, a flexible cover material positioned on at least an outer surface of the expandable stent, a nanoscale source of electrical energy embedded within the cover material, where the nanoscale source of electrical energy is mechanically activatable to produce the electrical energy, and antimicrobial particles distributed on or within a surface region of the cover material. The antimicrobial particles are electrically connected to the nanoscale source of electrical energy. When the active implantable medical device is placed in a body vessel and exposed to pressure changes and/or mechanical stresses, mechanical activation of the nanoscale source occurs, thereby enabling production of the electrical energy and powering of the antimicrobial particles.
Abstract: A medical device, such as a prosthesis, and method of forming the same are disclosed. The medical device includes a cover material and a reinforcement element, and may include a stent frame structure. The reinforcement element includes a plurality of bends disposed about a pattern axis. The pattern axis is arranged helically along the cover material.
Abstract: The disclosure is directed to a system for maintaining hemostasis during introducing or withdrawing an interventional device. The system includes a housing. The housing includes a first end, a second end and a side wall defining a housing chamber. The system also includes a first funnel-shaped member disposed at least partially within the housing chamber. The first funnel-shaped member includes an inner portion, a middle portion and an outer portion. The inner portion of the first funnel-shaped member includes an elastic orifice, which is aligned with the through channel of the housing. The first funnel-shaped member includes an open configuration and a closed configuration. When the first funnel-shaped member is in the closed configuration, the elastic orifice is substantially closed, and when the first funnel-shaped member is in the open configuration, an interventional device is introduced through the system and the elastic orifice is open.
June 3, 2019
December 3, 2020
Cook Medical Technologies LLC
Ralf SPINDLER, Dennis MADDOX, Becky BAUMGARTNER
Abstract: The present disclosure relates to woven and knitted fabrics including boron nitride nanotubes and to methods of manufacturing and using such materials. In one embodiment, these materials are incorporated into implantable medical devices such as stent graft devices and the like.
Abstract: A bifurcated stent graft includes a stent graft body that defines exactly one main body opening and at least two exit openings. The stent graft body includes at least one stent attached to a graft fabric material, and includes a dividing wall that divides a combined flow path, into a first flow path and a second flow path that each terminate at one of the respective exit openings. The dividing wall includes a thickness profile that terminates at a leading edge radius that extends across a width of the combined flow path.
Abstract: In one aspect, a radiopaque marker for a medical implant, such as a stent graft for aortic aneurism repair, includes a first radiopaque component connected to a second radiopaque component by a connection. The first radiopaque component includes a non-biodegradable radiopaque body. The radiopaque marker has a first configuration and a second configuration that differ from one another in at least one of volume and shape such that the first and second configurations produce different radiographic images. This change in radiopacity can provide useful information to a surgeon in the event that reintervention becomes necessary.
Abstract: The present disclosure relates to a graft material including a self-healing polymer layer and to implantable medical devices including such a graft material. The invention also relates to methods of using and manufacturing such graft materials and devices. In one embodiment, the implantable medical device is a stent graft.
Abstract: The present disclosure relates to a graft material including a reinforced layer and to implantable medical devices including such a graft material. The invention also relates to methods of using and manufacturing such graft materials and devices. In one embodiment the implantable medical device is a stent graft.
Abstract: The disclosure is directed to a system, device and method for data storage on implantable magnetizable fabric. The system includes implantable magnetizable fabric coupled to a graft segment of a prosthesis for being delivered into a body of a subject. The system includes information written on the implantable magnetizable fabric. The system further includes a magnetic detection device capable of, after the prosthesis is delivered into the body of the subject, detecting the implantable magnetizable fabric and accessing at least a portion of the information.
Abstract: The present disclosure relates to a layered graft material and to implantable medical devices including such a graft material. In one embodiment, the device is a stent-graft. In other embodiments, the invention relates to methods of manufacturing and using such devices. In one embodiment the graft is formed of at least three layers, including a folded central layer.
Abstract: A balloon expanded stent delivery system includes an inflation constraint, such as a wire, spirally wound about the longitudinal axis in contact with a balloon and attached to an underlying catheter. A balloon expanded stent is mounted about the balloon and the inflation constraint. The delivery system has a predeployment configuration with the balloon deflated and the stent unexpanded. The system has a deployment configuration in which the inflation constraint constrains the inflated balloon to a spiral shape, the stent is expanded and in contact with the balloon, and the stent has a flow directing surface with a spiral contour that matches the spiral shape of the balloon. In a postdeployment configuration, the stent retains the flow directing surface with the spiral contour.
Abstract: A multi-stage balloon catheter has a deflated state, a first inflation state at a first pressure and a second inflation state at a higher fluid pressure. In the first inflation state, the multi-stage balloon has a plurality of bulb segments separated by waist hoops that allow the multi-stage balloon to conform to match the curvature of a passageway. When pressure is increased in the multi-stage balloon from the first inflation state to the second inflation state, the waist locations expand either by breaking or stretching the waist restraints or by overcoming expansion resistance incorporated into the balloon material at the waist locations. The multi-stage balloon catheter may be used to implant a stent in a manner to conform and match a curved passageway rather than tending to straighten the passageway.
July 2, 2019
October 24, 2019
James Merk, Brent Mayle, Ralf Spindler, Davorin Skender
Abstract: A medical device, such as a prosthesis, may include a graft material and a pocket disposed along at least one of luminal and abluminal surfaces of the graft material. The pocket may include a pocket opening leading into an enclosed cavity. The enclosed cavity may be sized to receive at least a portion of a microsystem, and the pocket may be accessible in vivo for removal of the microsystem from the pocket.
Abstract: A balloon catheter includes a first balloon positioned inside of a second balloon, both of which are mounted about a catheter and fluidly connected to respective inflation lumens. In a first inflated configuration, the second balloon is inflated and has a shape that includes a plurality of bulb segments, with each two consecutive bulb segments being separated by a waist hoop. In a second inflated configuration both the inner and outer balloons are inflated, and the inner balloon bears radially outwardly against the waist hoop of the outer balloon such that the waist hoop of the outer balloon has a larger diameter in the second inflated configuration than in the first inflated configuration. The bulb segment separated by waist hoops enable the balloon catheter to conform to curved passageways, such as during the implementation of a stent.
September 18, 2017
Date of Patent:
October 8, 2019
Cook Medical Technologies LLC
Ralf Spindler, James Merk, Brent Mayle, Thomas Lysgaard
Abstract: A bifurcated stent graft includes a stent graft body that defines exactly one main body opening and two exit openings. The stent graft body includes at least one stent attached to a graft fabric material, and includes a dividing wall that divides a combined flow path, into a first flow path and a second flow path that each terminate at one of the respective exit openings. The dividing wall includes a thickness profile that is equal to or thinner than a wall thickness of the graft fabric material, terminates a leading rounded surface, and extends across a width of the combined flow path.