Patents by Inventor Ralf Thiericke

Ralf Thiericke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Device for fully automated solid phase extraction
    Patent number: 7223370
    Abstract: Device for automatically implementing the SPE method, with a two-dimensional needle arrangement which is suitable for removing substances from different two-dimensional specimen vessel arrangements and dispensing them under pressure into a two-dimensional cartridge arrangement.
    Type: Grant
    Filed: August 20, 2001
    Date of Patent: May 29, 2007
    Assignee: CyBio AG
    Inventors: Thomas Moore, Uwe Naumann, Wolfgang Kraemer, Peter Zimmermann, Sebastian Pobering, Holger Licht, Gerd Ebert, Ralf Thiericke, Ingrid Schmid
  • Device for fully automated solid phase extraction
    Publication number: 20040013572
    Abstract: Device for automatically implementing the SPE method, with a two-dimensional needle arrangement which is suitable for removing substances from different two-dimensional specimen vessel arrangements and dispensing them under pressure into a two-dimensional cartridge arrangement.
    Type: Application
    Filed: July 16, 2003
    Publication date: January 22, 2004
    Inventors: Thomas Moore, Uwe Naumann, Wolfgang Kraemer, Peter Zimmermann, Sebastian Pobering, Holger Licht, Gerd Bert, Ralf Thiericke, Ingrid Schmid
  • Ergoline amine derivatives with blood pressure lowering effect
    Patent number: 6358967
    Abstract: The invention relates to novel derivatives of ergoline of the general formula 1 in which R1 together with the two adjacent N atoms is the residue of a diamine and R4 together with the two adjacent carbonyl groups is the residue of a dicarboxylic acid. R2, R3, R6, R7, R8 can be H or an organic radical. R7 and R8 are H or together are a bond. The compounds show a strong antihypertensive effect. These effects moreover occur after intravenous and enteral administration even at dosages in the region of a few &mgr;g/kg (body weight). The compounds can accordingly be used as pharmaceuticals for hypertensive diseases in human medicine.
    Type: Grant
    Filed: April 19, 2001
    Date of Patent: March 19, 2002
    Assignee: CyBio Screening GmbH
    Inventors: Ralf Wyrwa, Albert Haertl, Erika Glusa, Susanne Grabley, Ralf Thiericke
  • Oasomycins
    Patent number: 5189150
    Abstract: Novel macrolactones with pharmacological effects can be prepared with the aid of Streptoverticillium and Streptomycetes strains.
    Type: Grant
    Filed: October 24, 1991
    Date of Patent: February 23, 1993
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Axel Zeeck, Siegrid Philipps, Susanne Grabley, Ernold Granzer, Klaus Hutter, Ralf Thiericke, Joachim Wink
  • Manumycin derivatives and the use thereof
    Patent number: 5079263
    Abstract: R.sup.2 is H or OH;R.sup.3 is H, OH, OCH.sub.3, CH.sub.3 or NH.sub.2 ;Rhu 4 is H, OH, OCH.sub.3, NH.sub.2 or ##STR2## The compounds of the formula I are prepared by fermentation of the strain Streptomyces parvulus DSM 40722 in the presence of substituted benzoic acids of the general formula II ##STR3## where R.sup.1 is H or OH;R.sup.2 is H or OH;R.sup.3 is H, OH, OCH.sub.3, CH.sub.3 or NH.sub.2 ;R.sup.4 is H, OH, OCH.sub.3 or NH.sub.2,and they inhibit Leukocyte elastase and can be used as pharmaceuticals.
    Type: Grant
    Filed: December 2, 1988
    Date of Patent: January 7, 1992
    Assignee: Behringwerke Aktiengesellschaft
    Inventors: Axel Zeeck, Ralf Thiericke, Hans Zahner, Gerhard Dickneite, Hans H. Sedlacek