Patents by Inventor Ralf Warrass
Ralf Warrass has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20240058366Abstract: This invention relates to methods of treatment and prevention of mastitis in animals by orthosomycin antimicrobial compounds.Type: ApplicationFiled: December 23, 2021Publication date: February 22, 2024Applicant: Intervet Inc.Inventors: Ralf Warrass, Joachim Ullrich
-
Publication number: 20230000813Abstract: The present invention provides compounds for use in the treatment of respiratory diseases of animals, especially Bovine or Swine Respiratory disease (BRD and SRD).Type: ApplicationFiled: June 21, 2022Publication date: January 5, 2023Applicant: Intervet Inc.Inventors: Thorsten Meyer, Ralf Warrass, Joachim Ullrich, Michael Berger, Michael Linder
-
Patent number: 11406617Abstract: The present invention provides compounds for use in the treatment of respiratory diseases of animals, especially Bovine or Swine Respiratory disease (BRD and SRD).Type: GrantFiled: December 22, 2017Date of Patent: August 9, 2022Assignee: Intervet Inc.Inventors: Thorsten Meyer, Ralf Warrass, Joachim Ullrich, Michael Berger, Michael Linder
-
Publication number: 20220041547Abstract: The present invention discloses compounds that are useful in the treatment of respiratory diseases of animals, especially Bovine or Swine Respiratory disease (BRD and SRD).Type: ApplicationFiled: May 10, 2021Publication date: February 10, 2022Applicant: Intervet Inc.Inventors: Michael Berger, Thorsten Meyer, Joachim Ullrich, Ralf Warrass
-
Publication number: 20210347730Abstract: The present invention provides compounds of formula (I) for use in the treatment of respiratory diseases of animals, especially Bovine or Swine Respiratory disease (BRD and SRD).Type: ApplicationFiled: June 24, 2019Publication date: November 11, 2021Applicant: Intervet Inc.Inventors: Thorsten Meyer, Michael Berger, Ralf Warrass, Joachim Ullrich
-
Publication number: 20210292284Abstract: The present invention discloses compounds that are useful in the treatment of respiratory diseases of animals, especially Bovine or Swine Respiratory disease (BRD and SRD)Type: ApplicationFiled: June 24, 2019Publication date: September 23, 2021Applicant: Intervet Inc.Inventors: Thorsten Meyer, Michael Berger, Ralf Warrass, Joachim Ullrich
-
Patent number: 11034650Abstract: The present invention discloses compounds of formula (I) that are useful in the treatment of respiratory diseases of animals, especially Bovine or Swine Respiratory disease (BRD and SRD).Type: GrantFiled: December 22, 2017Date of Patent: June 15, 2021Assignee: Intervet Inc.Inventors: Michael Berger, Thorsten Meyer, Joachim Ullrich, Ralf Warrass
-
Publication number: 20200085779Abstract: The present invention provides compounds for use in the treatment of respiratory diseases of animals, especially Bovine or Swine Respiratory disease (BRD and SRD).Type: ApplicationFiled: December 22, 2017Publication date: March 19, 2020Applicant: Intervet Inc.Inventors: Thorsten Meyer, Ralf Warrass, Joachim Ullrich, Michael Berger, Michael Linder
-
Publication number: 20190352256Abstract: The present invention discloses compounds of formula (I) that are useful in the treatment of respiratory diseases of animals, especially Bovine or Swine Respiratory disease (BRD and SRD).Type: ApplicationFiled: December 22, 2017Publication date: November 21, 2019Applicant: Intervet Inc.Inventors: Michael Berger, Thorsten Meyer, Joachim Ullrich, Ralf Warrass
-
Publication number: 20140088032Abstract: The invention relates to a veterinary composition for intramammary administration comprising a combination of an antibacterial agent and a Toll-Like-Receptor (TLR) agonist and to the use of said composition for the treatment of mastitis in lactating ruminants.Type: ApplicationFiled: May 11, 2012Publication date: March 27, 2014Inventors: Thomas Simon Ilg, Ralf Warrass, Peter Gerardus Franciscus Cox, Carlos De Sa, Karine Pere
-
Patent number: 8518900Abstract: Described are methods for making macrolides, and, in particular, a method for making optionally substituted 20,23-dipiperidinyl-5-O-mycaminosyl-tylonolide and derivatives thereof, as well as uses of macrolides to make medicaments, methods of treatment using macrolides, and methods for making intermediates that, among other uses, may be used to make macrolides. Also described are solvated and non-solvated crystalline forms of 20,23-dipiperidinyl-5-O-mycaminosyl-tylonolide, as well as methods for making such crystalline forms, medicaments comprising (or derived from) such crystalline forms, methods for making medicaments comprising (or derived from) such crystalline forms, methods of treatment using such crystalline forms, and kits comprising such crystalline forms.Type: GrantFiled: January 26, 2012Date of Patent: August 27, 2013Assignee: Intervet International B.V.Inventors: Ralf Warrass, Fritz Blatter, Meinrad Brenner, Guixan Hu, Timo Rager
-
Patent number: 8461121Abstract: Described are methods for making macrolides, and, in particular, a method for making optionally substituted 20,23-dipiperidinyl-5-O-mycaminosyl-tylonolide and derivatives thereof, as well as uses of macrolides to make medicaments, methods of treatment using macrolides, and methods for making intermediates that, inter alia, may be used to make macrolides. Also described are solvated and non-solvated crystalline forms of 20,23-dipiperidinyl-5-O-mycaminosyl-tylonolide, as well as methods for making such crystalline forms, medicaments comprising (or derived from) such crystalline forms, methods for making medicaments comprising (or derived from) such crystalline forms, methods of treatment using such crystalline forms, and kits comprising such crystalline forms.Type: GrantFiled: February 22, 2012Date of Patent: June 11, 2013Assignee: Intervet International B.V.Inventors: Ralf Warrass, Fritz Blatter, Timo Rager
-
Patent number: 8263753Abstract: This invention relates to a method for making macrolides, and, in particular, a method for making optionally substituted 20,23-dipiperidinyl-5-O-mycaminosyl-tylonolide and derivatives thereof, as well as uses of macrolides to make medicaments, methods of treatment using macrolides, and methods for making intermediates that, inter alia, may be used to make macrolides. This invention also relates to solvated and non-solvated crystalline forms of 20,23-dipiperidinyl-5-O-mycaminosyl-tylonolide, as well as methods for making such crystalline forms, medicaments comprising (or derived from) such crystalline forms, methods for making medicaments comprising (or derived from) such crystalline forms, methods of treatment using such crystalline forms, and kits comprising such crystalline forms.Type: GrantFiled: July 30, 2010Date of Patent: September 11, 2012Assignee: Intervet International B.V.Inventors: Monika Brink, Hans P. Niedermann, Tanja Schweisel, Stephan Veit, Kerstin Fleischhauer, Ralf Warrass, Heinz-Jorg Wennesheimer
-
Patent number: 8227429Abstract: This invention relates to a method for making macrolides, and, in particular, a method for making optionally substituted 20,23-dipiperidinyl-5-O-mycaminosyl-tylonolide and derivatives thereof, as well as uses of macrolides to make medicaments, methods of treatment using macrolides, and methods for making intermediates that, inter alia, may be used to make macrolides. This invention also relates to solvated and non-solvated crystalline forms of 20,23-dipiperidinyl-5-O-mycaminosyl-tylonolide, as well as methods for making such crystalline forms, medicaments comprising (or derived from) such crystalline forms, methods for making medicaments comprising (or derived from) such crystalline forms, methods of treatment using such crystalline forms, and kits comprising such crystalline forms.Type: GrantFiled: July 26, 2007Date of Patent: July 24, 2012Assignee: Intervet International B.V.Inventors: Ralf Warrass, Fritz Blatter, Meinrad Brenner, Guixan Hu, Tamo Rager
-
Publication number: 20120122808Abstract: Described are methods for making macrolides, and, in particular, a method for making optionally substituted 20,23-dipiperidinyl-5-O-mycaminosyl-tylonolide and derivatives thereof, as well as uses of macrolides to make medicaments, methods of treatment using macrolides, and methods for making intermediates that, among other uses, may be used to make macrolides. Also described are solvated and non-solvated crystalline forms of 20,23-dipiperidinyl-5-O-mycaminosyl-tylonolide, as well as methods for making such crystalline forms, medicaments comprising (or derived from) such crystalline forms, methods for making medicaments comprising (or derived from) such crystalline forms, methods of treatment using such crystalline forms, and kits comprising such crystalline forms.Type: ApplicationFiled: January 26, 2012Publication date: May 17, 2012Applicant: INTERVET INTERNATIONAL B.V.Inventors: Ralf Warrass, Fritz Blatter, Meinrad Brenner, Guixan Hu, Timo Rager
-
Publication number: 20110288286Abstract: A process is disclosed for the production of cyclic di-guanosine monophosphate (c-di-GMP) without the use of protecting groups by means of an enzymatic synthesis. The process comprises the coupling of two guanosine triphosphate (GTP) molecules so as to form a c-di-GMP molecule. This is done under the influence of a mutant diguanylate cyclase (DGC) comprising the amino acid sequence V153M154G155G156. It has been found that the DGC is obtainable from inclusion bodies, and therewith can be made available in amounts sufficient to improve the c-di-GMP synthesis. Particularly, the latter synthesis can be conducted in a one-pot method starting from commercially available bulk chemicals and allows upscaling to a commercial production scale.Type: ApplicationFiled: December 7, 2009Publication date: November 24, 2011Inventors: Thomas Simon Ilg, Volker Spehr, Ralf Warrass
-
Publication number: 20110053875Abstract: This invention relates to a method for making macrolides, and, in particular, a method for making optionally substituted 20,23-dipiperidinyl-5-O-mycaminosyl-tylonolide and derivatives thereof, as well as uses of macrolides to make medicaments, methods of treatment using macrolides, and methods for making intermediates that, inter alia, may be used to make macrolides. This invention also relates to solvated and non-solvated crystalline forms of 20,23-dipiperidinyl-5-O-mycaminosyl-tylonolide, as well as methods for making such crystalline forms, medicaments comprising (or derived from) such crystalline forms, methods for making medicaments comprising (or derived from) such crystalline forms, methods of treatment using such crystalline forms, and kits comprising such crystalline forms.Type: ApplicationFiled: July 30, 2010Publication date: March 3, 2011Inventors: Fritz Blatter, Meinrad Brenner, Monika Brink, Kerstin Fleischhauer, Guixian Hu, Hans Peter Niedermann, Timo Rager, Tanja Schweisel, Stephan Veit, Ralf Warrass, Heinz-Jörg Wennesheimer
-
Publication number: 20090042815Abstract: This invention relates to a method for making macrolides, and, in particular, a method for making optionally substituted 20,23-dipiperidinyl-5-O-mycaminosyl-tylonolide and derivatives thereof, as well as uses of macrolides to make medicaments, methods of treatment using macrolides, and methods for making intermediates that, inter alia, may be used to make macrolides. This invention also relates to solvated and non-solvated crystalline forms of 20,23-dipiperidinyl-5-O-mycaminosyl-tylonolide, as well as methods for making such crystalline forms, medicaments comprising (or derived from) such crystalline forms, methods for making medicaments comprising (or derived from) such crystalline forms, methods of treatment using such crystalline forms, and kits comprising such crystalline forms.Type: ApplicationFiled: July 26, 2007Publication date: February 12, 2009Applicant: Intervet International B.V.Inventors: Fritz Blatter, Meinrad Brenner, Monika Brink, Kerstin Fleischhauer, Guixian Hu, Hans Peter Niedermann, Timo Rager, Tanja Schweisel, Stephan Veit, Ralf Warrass, Heinz-Jorg Wennesheimer