Patents by Inventor Ralf Wolleschensky

Ralf Wolleschensky has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7463344
    Abstract: Arrangement and method for the optical detection of light radiation which is excited and/or backscattered in a specimen, wherein the illumination of the specimen and/or the detection of the specimen light is carried out by at least two objectives arranged on different sides of the specimen. The specimen illumination is focused in or in the vicinity of a pupil plane of the beam path between the specimen plane and the detection plane at least on one axis and an element for the spatial separation of the illumination light from the detection light are provided in this plane.
    Type: Grant
    Filed: July 9, 2004
    Date of Patent: December 9, 2008
    Assignee: Carl Zeiss MicroImaging GmbH
    Inventors: Ralf Wolleschensky, Michael Kempe
  • Publication number: 20080285123
    Abstract: Raster scanning light microscope with line pattern scanning with at least one illumination module, in which the means to achieve a variable partition of the laser light into least two illumination channels are envisioned and joint illumination of a sample takes place at the same or at different areas of the sample.
    Type: Application
    Filed: November 28, 2007
    Publication date: November 20, 2008
    Inventors: Joerg-Michael Funk, Ralf Wolleschensky, Bernhard Zimmermann, Stefan Wilhelm, Ralf Engelmann
  • Publication number: 20080252945
    Abstract: A device for generating an image of an object is provided, comprising an illumination module, by means of which the object can be illuminated with a pattern whose phase is altered temporally a recording module by means of which a plurality of recordings of the object are carried out during the phase change of the patter, and a processing module, which generates the image from the recordings, wherein the illumination module moves a light beam over the object and modulates its intensity synchronously with the movement such that the beam generates the pattern in scanning fashion.
    Type: Application
    Filed: September 14, 2006
    Publication date: October 16, 2008
    Inventors: Michael Kempe, Ralf Wolleschensky
  • Publication number: 20080192128
    Abstract: A device for generating an image of an object is provided, comprising an illumination module, by means of which the object can be illuminated with a pattern whose phase is altered temporally, a recording module, by means of which a plurality of recordings of the object are carried out during the phase change of the pattern, and a processing module, which generates the image from the recordings, wherein the illumination module moves a light beam over the object and modulates its intensity synchronously with the movement such that the beam generates the pattern in scanning fashion.
    Type: Application
    Filed: March 26, 2008
    Publication date: August 14, 2008
    Inventors: Michael Kempe, Ralf Wolleschensky
  • Patent number: 7411166
    Abstract: A Device for coupling a short pulse laser into a microscope beam path, wherein the spectral components of the laser radiation are spatially separated by means of a dispersive element, the individual spectral components are manipulated and are then spatially superimposed again by means of another dispersive element.
    Type: Grant
    Filed: April 18, 2006
    Date of Patent: August 12, 2008
    Assignee: Carl Zeiss MicroImaging GmbH
    Inventors: Ralf Wolleschensky, Thomas Feurer, Roland Sauerbrey
  • Patent number: 7400433
    Abstract: Adjustable pinhole, particularly for the illumination beam path and/or detection beam path of a laser scanning microscope, wherein the pinhole is defined by foil edges which are adjustable relative to one another, and at least two foils, each with at least one straight edge, are advantageously arranged relative to one another and/or connected to one another in such a way that their edges describe an L-shape and the L-shaped connection pieces are arranged on one another in such a way that they define a rhombic or square light passage and they are moved relative to one another for adjusting the pinhole.
    Type: Grant
    Filed: October 29, 2007
    Date of Patent: July 15, 2008
    Assignee: Carl Zeiss MicroImaging GmbH
    Inventors: Karlheinz Bartzke, Ralf Wolleschensky, Karl-Heinz Klopfleisch, Jens Hofmann
  • Publication number: 20080166041
    Abstract: A device for optically sensing a specimen with a large depth of field has a lighting module which illuminates a zone of the specimen during a predetermined measurement period with a pattern whose phase is modified in time during the measurement period, generating a specimen light to which a corresponding time-variable phase is imparted. The device also includes a detection module having a space-resolving detection zone which records the specimen zone and has multiple recording pixels, two analysis channels which can be connected to the recording pixels, and an analysis unit is connected to both analysis channels.
    Type: Application
    Filed: March 19, 2008
    Publication date: July 10, 2008
    Inventor: Ralf Wolleschensky
  • Publication number: 20080149818
    Abstract: Procedure for the image acquisition of objects by means of a light raster microscope with line by line scanning, whereas a scanning of the specimen for the creation of a specimen image occurs in scanning steps and the distance between at least two scanning steps is variably adjustable and at least a second scanning of the specimen occurs, during which the position of the scanning steps is shifted with regard to the scanning direction, whereas preferably a line by line scanning of the specimen is carried out.
    Type: Application
    Filed: November 28, 2007
    Publication date: June 26, 2008
    Inventors: Ralf Wolleschensky, Frank Hecht, Ralf Engelmann
  • Patent number: 7388713
    Abstract: Optical scanning microscope with linear scanning and with illumination of a specimen via a beam splitter, which is arranged in an objective pupil and includes at least a reflecting first portion and at least a transmitting second portion, whereby the reflecting portion serves to couple in the illumination light and the transmitting portion serves to pass the detection light in the detection direction or the transmitting portion serves to couple in the illumination light and the reflecting portion serves to couple out the detection light, with a first scanning arrangement, whereby mechanism is provided in the detection light path for the overlay of at least one further scanning arrangement for illumination and detection.
    Type: Grant
    Filed: October 19, 2004
    Date of Patent: June 17, 2008
    Assignee: Carl Zeiss Jena GmbH
    Inventor: Ralf Wolleschensky
  • Patent number: 7369307
    Abstract: In a light raster scanning microscope with a spot illumination arrangement (2) which provides an illumination beam for the illumination of a sample (23) in the form of points or point groups, a scanning arrangement (3, 4) which guides the illumination beam in the form of points or point groups over the sample in a manner so as to scan, a spot detector arrangement (5) which images, via the scanning arrangement (3, 4), the illuminated point or point group spot of the sample (23) by means of at least one confocal aperture (26) on at least one detector unit (28), and a control unit which controls the scanning arrangement (3, 4) and reads out the spot detector arrangement (5), it is provided that, in addition, a wide-field illumination source (29, 34) is provided which illuminates the sample (23) and that the control unit controls the scanning arrangement (3, 4) during the operation of the wide-field illumination source (29, 34) and reads out the spot detector arrangement (5) in such a manner that an image of the
    Type: Grant
    Filed: October 19, 2004
    Date of Patent: May 6, 2008
    Assignee: Carl Zeiss Jena GmbH
    Inventor: Ralf Wolleschensky
  • Patent number: 7369305
    Abstract: For a confocal scanning electron microscope (1) an optical zoom system (41) is provided, which not only makes a zoom function possible, in that a variable magnification of an image is possible, but rather which additionally produces a pupil image in the illuminating beam path (IB) [BS] and thereby makes a variable imaging length possible (distance between the original pupil (En.P) [EP] and the imaged/reproduced pupil (Ex.P) [AP]) so that axially varying objective pupil positions can thereby be compensated.
    Type: Grant
    Filed: October 19, 2004
    Date of Patent: May 6, 2008
    Assignee: Carl Zeiss Jena GmbH
    Inventors: Ralf Wolleschensky, Joerg Steinert, Michael Goelles, Kristina Uhlendorf
  • Publication number: 20080088907
    Abstract: Device for controlling light radiation, which is excited in a specimen and/or which is backscattered and/or reflected and which contains one or more wavelengths, at a plurality of light outlets, wherein a separation of the light radiation into differently polarized components is carried out; and the components of the excitation radiation and/or detection radiation are affected in their polarization by means of a preferably birefringent, preferably acousto-optic or electro-optic medium, which changes the ordinary and extraordinary refractive index.
    Type: Application
    Filed: November 30, 2007
    Publication date: April 17, 2008
    Inventor: Ralf Wolleschensky
  • Publication number: 20080088920
    Abstract: Microscope, in particular an optical scanning microscope with illumination of a specimen via a beam splitter, which is arranged in an objective pupil and includes at least a reflecting first portion and at least a transmitting second portion, whereby the reflecting portion serves to couple in the illumination light and the transmitting portion serves to pass the detection light in the detection direction or the transmitting portion serves to couple in the illumination light and the reflecting portion serves to couple out the detection light, with a first scanning arrangement. Means are provided in the detection light path for the overlay of at least one further scanning arrangement for illumination and detection.
    Type: Application
    Filed: October 19, 2007
    Publication date: April 17, 2008
    Inventor: Ralf WOLLESCHENSKY
  • Publication number: 20080068710
    Abstract: Arrangement for microscopic observation and/or detection of a sample that is at least partially transparent by way of a microscope objective, whereby an illumination of the sample outside the objective is carried out from at least from one side at an angle to the optical axis of the objective and the illumination light is focused on the sample with a smaller aperture than that of the viewing objective and that a coupling of the illumination light over a beam splitter, preferably in the objective pupil, is carried out for coupling, at its circumference, slightly expanding transmitting or reflecting areas for steering the illumination light to the sample, but otherwise is designed so that it is reflecting or transmitting for the sample light on the rest of the area.
    Type: Application
    Filed: June 11, 2007
    Publication date: March 20, 2008
    Applicant: CARL ZEISS JENA GMBH
    Inventor: Ralf Wolleschensky
  • Publication number: 20080062511
    Abstract: Laser scanning microscope for fluorescence testing, in which the illumination and detection rays are bound optically through a dichroic main beam splitter, the detected probe light being led to several detectors by means of a secondary beam splitter and the angle of incidence of the illumination light and/or the angle of incidence of the probe light at the splitter surface of at least the main beam splitter or at least the secondary splitter is less than 45 degrees.
    Type: Application
    Filed: July 30, 2007
    Publication date: March 13, 2008
    Inventor: Ralf Wolleschensky
  • Publication number: 20080049893
    Abstract: A rotary device (1) is provided for an optic tomograph, with the sample carrier (4) with the object (5) to be examined being rotational around a predetermined axis (6) of the object, with the rotary device (1) having a rotary module (8; 15), which can cause a rotation around a first rotary axis (10), a first positioning module (7) connected to the rotary module (8), by which the first rotary module (8; 15) can be positioned along the first rotary axis (10), and a second positioning module (9; 11; 12; 16; 17) connected to the rotary module (8; 15), at which the sample carrier (4) with the object (5) to be examined can be fastened, allowing the axis (6) of the object to be positioned in reference to the first rotary axis (10) by the second positioning module (9; 11, 12; 16; 17) such that a rotation of the rotary module (8; 15) rotates the object (5) around the axis (6) of the object.
    Type: Application
    Filed: August 27, 2007
    Publication date: February 28, 2008
    Inventors: Karlheinz BARTZKE, Georg GUENTHER, Ralf WOLLESCHENSKY, Michael WEGWERTH
  • Publication number: 20080049221
    Abstract: Method and arrangement for changing the spectral composition and/or intensity of illumination light and/or specimen light in an adjustable manner, wherein a spatial separation into radiation components of different polarization is carried out with a first polarizing device, a spectral, spatial splitting of at least one radiation component is carried out with first dispersion device, the polarization state of at least one part of the spectrally spatially split radiation component is changed, and a spatial separation and/or combination of radiation components of different polarization are/is carried out by a second polarizing device, wherein a spatial combination of radiation components which are changed and not changed with respect to their polarization state is advantageously carried out by a second dispersion device.
    Type: Application
    Filed: August 3, 2007
    Publication date: February 28, 2008
    Inventor: RALF WOLLESCHENSKY
  • Publication number: 20080049294
    Abstract: Adjustable pinhole, particularly for the illumination beam path and/or detection beam path of a laser scanning microscope, wherein the pinhole is defined by foil edges which are adjustable relative to one another, and at least two foils, each with at least one straight edge, are advantageously arranged relative to one another and/or connected to one another in such a way that their edges describe an L-shape and the L-shaped connection pieces are arranged on one another in such a way that they define a rhombic or square light passage and they are moved relative to one another for adjusting the pinhole.
    Type: Application
    Filed: October 29, 2007
    Publication date: February 28, 2008
    Inventors: KARLHEINZ BARTZKE, Ralf Wolleschensky, Karl-Heinz Klopfleisch, Jens Hofmann
  • Publication number: 20080048105
    Abstract: Procedure for the image acquisition of objects by means of a light raster microscope, whereas a scanning of the probe for the creation of a probe image occurs in scanning steps and the distance between at least two scanning steps is variably adjustable and at least a second scanning of the probe occurs, during which the position of the scanning steps is shifted with regard to the scanning direction, whereas preferably a line by line scanning of the probe is carried out.
    Type: Application
    Filed: March 12, 2007
    Publication date: February 28, 2008
    Applicant: CARL ZEISS JENA GMBH
    Inventors: Ralf Wolleschensky, Frank Hecht, Ralf Engelmann
  • Publication number: 20080030850
    Abstract: Arrangement for microscopic observation and/or detection of a sample that is at least partially transparent by way of a microscope objective in a light scanning microscope with line-shaped illumination, whereby an illumination of the sample outside the objective is carried out from at least from one side at an angle to the optical axis of the objective and the illumination light is focused on the sample with a smaller aperture than that of the viewing objective and that a coupling of the illumination light over a beam splitter, preferably in the objective pupil, is carried out for coupling, at its circumference, slightly expanding transmitting or reflecting areas for steering the illumination light to the sample, but otherwise is designed so that it is reflecting or transmitting for the sample light on the rest of the area.
    Type: Application
    Filed: June 22, 2007
    Publication date: February 7, 2008
    Applicant: CARL ZEISS JENA GMBH
    Inventor: Ralf Wolleschensky