Patents by Inventor Ralf Wyrwa

Ralf Wyrwa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Estriol and estetrol prodrugs
    Publication number: 20050277625
    Abstract: This invention provides estriol and estetrol prodrugs of general formula (I), in which group Y is bonded to the steroid process for their production, pharmaceutical compositions that contain these compounds, as well as their use for the production of pharmaceutical agents with estrogenic action.
    Type: Application
    Filed: May 23, 2005
    Publication date: December 15, 2005
    Inventors: Ralf Wyrwa, Sven Ring, Peter Droescher, Alexander Hillisch, Walter Elger, Birgitt Schneider, Gudrun Reddersen
  • D-homo-17-chlor-16(17)-ene steroids
    Publication number: 20050234111
    Abstract: The invention relates to D-homo-17-chlor-16(17)-ene steroids of formula I with androgenic activity process for their production and pharmaceutical compositions that contain these compounds, as well as their use for the production of pharmaceutical agents.
    Type: Application
    Filed: April 8, 2005
    Publication date: October 20, 2005
    Inventors: Sven Ring, Ralf Wyrwa, Guenter Kaufmann
  • Delta15-D-Homosteroids with androgenic action
    Publication number: 20050131076
    Abstract: The invention relates to ?15-D-homosteroids of general formula (I) process for their production and pharmaceutical compositions that contain these compounds. The compounds of general formula I according to the invention have androgenic activity.
    Type: Application
    Filed: August 23, 2004
    Publication date: June 16, 2005
    Inventors: Ralf Wyrwa, Sven Ring, Guenter Kaufmann, Walter Elger, Birgitt Schneider
  • 17Alpha fluoroalkyl steroids, method for producing the same and pharmaceutical compositions containing said compounds
    Publication number: 20040024231
    Abstract: The invention relates to 17&agr; fluoroalkyl steroids of the general formula (I). STEROID (I), wherein R3 represents a group of the formula CnFmHo, wherein n=1, 2, 3, 4, 5 or 6, m>1 and m+o=2n+1. The invention further relates to methods for producing the same and to compositions that contain said compounds. The inventive composition of the general formula (I) possess androgenic activity.
    Type: Application
    Filed: August 12, 2003
    Publication date: February 5, 2004
    Inventors: Sven Ring, Guenter Kaufmann, Ralf Wyrwa, Walter Elger
  • Ergoline amine derivatives with blood pressure lowering effect
    Patent number: 6358967
    Abstract: The invention relates to novel derivatives of ergoline of the general formula 1 in which R1 together with the two adjacent N atoms is the residue of a diamine and R4 together with the two adjacent carbonyl groups is the residue of a dicarboxylic acid. R2, R3, R6, R7, R8 can be H or an organic radical. R7 and R8 are H or together are a bond. The compounds show a strong antihypertensive effect. These effects moreover occur after intravenous and enteral administration even at dosages in the region of a few &mgr;g/kg (body weight). The compounds can accordingly be used as pharmaceuticals for hypertensive diseases in human medicine.
    Type: Grant
    Filed: April 19, 2001
    Date of Patent: March 19, 2002
    Assignee: CyBio Screening GmbH
    Inventors: Ralf Wyrwa, Albert Haertl, Erika Glusa, Susanne Grabley, Ralf Thiericke
  • Olefin polymerization with group 4 metal-containing organosilicon dendrimers
    Patent number: 6313239
    Abstract: Group 4 metal-containing organosilicon dendrimers are described. Also described are methods for synthesizing the dendrimers. The dendrimers can be useful in several applications including as olefin polymerization and copolymerization catalysts and as silane polymerization catalysts.
    Type: Grant
    Filed: March 5, 1996
    Date of Patent: November 6, 2001
    Assignees: Bayer Corporation, Bayer A.G., Massachusetts Institute of Technology
    Inventors: Dietmar Seyferth, Ralf Wyrwa, Uli W. Franz, Sigurd Becke
  • Group 4 metal-containing organosilicon dendrimers and method for synthesizing organosilicon denrimers
    Patent number: 5969073
    Abstract: Group 4 metal-containing organosilicon dendrimers are described. Also described are methods for synthesizing the dendrimers. The dendrimers can be useful in several applications including as olefin polymerization and copolymerization catalysts and as silane polymerization catalysts.
    Type: Grant
    Filed: April 10, 1997
    Date of Patent: October 19, 1999
    Assignee: Massachusetts Institute of Technology
    Inventors: Dietmar Seyferth, Ralf Wyrwa