Patents by Inventor Ralph Brattsand

Ralph Brattsand has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of rofleponide in the treatment of irritable bowel syndrome (ibs)
    Publication number: 20030004214
    Abstract: The invention provides the use of rofleponide, its esters and salts in the manufacture of a medicament for use in the treatment of irritable bowel syndrome (IBS) and pharmaceutical formulations for use in such treatment.
    Type: Application
    Filed: July 19, 2002
    Publication date: January 2, 2003
    Inventor: Ralph Brattsand
  • Estrogens
    Patent number: 6043236
    Abstract: Compounds of the formula I ##STR1## a process for their preparation, their use in the treatment of autoimmune disorders as well as new intermediates for their preparation.
    Type: Grant
    Filed: April 23, 1997
    Date of Patent: March 28, 2000
    Assignee: Astra Aktiebolag
    Inventors: Ralph Brattsand, Rikard Holmdahl, Liselotte Jansson, Marjana Loncar, Lars Pettersson
  • Processes for the production of anti-inflammatory steroids
    Patent number: 5939409
    Abstract: Disclosed are processes for preparing the 22R and 22S epimers of the compound ##STR1## The processes involve acetalization, transacetalization, hydrolysis (of an ester) or hydrogenation (of a diene) of an appropriate starting material. Also disclosed are pharmaceutical compositions comprising the compounds produced by the processes and methods of treatment of inflammatory and allergic conditions employing the compounds.
    Type: Grant
    Filed: October 7, 1997
    Date of Patent: August 17, 1999
    Assignee: Astra Aktiebolag
    Inventors: Paul Andersson, Bengt Axelsson, Ralph Brattsand, Arne Thalen
  • Fluorinated steroids
    Patent number: 5674861
    Abstract: Disclosed are the 22R and 22S epimers of compounds of the formula ##STR1## wherein X.sub.1 represents a fluorine atom, and X.sub.2 represents a hydrogen atom or a fluorine atom. Also disclosed are processes for the preparation of the compounds, pharmaceutical compositions comprising the compounds and methods of treatment of inflammatory and allergic conditions employing the compounds.
    Type: Grant
    Filed: August 31, 1993
    Date of Patent: October 7, 1997
    Assignee: Astra Aktiebolag
    Inventors: Paul Andersson, Bengt Axelsson, Ralph Brattsand, Arne Thalen
  • Steroid esters
    Patent number: 5614514
    Abstract: Compounds of the general formula (I), ##STR1## in which formula the 1,2-position is saturated or is a double bond, R.sub.1 is hydrogen or a straight or branched hydrocarbon chain, R.sub.2 is hydrogen or a straight or branched hydrocarbon chain, R.sub.3 is acyl, X.sub.1 is hydrogen or halogen, X.sub.2 is hydrogen or halogen and provided that 1) R.sub.1 and R.sub.2 are not simultaneously hydrogen, 2) X.sub.1 and X.sub.2 are not simultaneously hydrogen, 3) when the 1,2-position is a double bond, R.sub.1 and R.sub.2 are not simultaneously methyl groups, 4) when the 1,2-position is a double, R.sub.1 is a hydrogen atom and R.sub.2 is a straight or branched hydrocarbon chain having 1-10 carbon atoms R.sub.3 is acyl having 11-20 carbon atoms, processes for their preparation, pharmaceutical preparations containing them and the use of the compounds in the treatment of inflammatory and allergic conditions.
    Type: Grant
    Filed: August 24, 1993
    Date of Patent: March 25, 1997
    Assignee: Aktiebolaget Astra
    Inventors: Bengt Axelsson, Ralph Brattsand, Leif Kallstrom, Arne Thalen