Abstract: Systems, methods and devices for the monitoring of the metabolism and the health of cultured cells are disclosed. The devices simplify the loading of cells and enable loading under sterile conditions. The devices also allow for the culture, measuring and monitoring of the metabolism of a population of cells, and in particular, the accurate measuring of metabolic states simultaneously in multiple cell populations.

Abstract: A female connector for releasable coupling with a male connector is disclosed herein. The male connector defines a fluid conduit and includes a male end adapted to be received within the female connector. The male end includes a coupling feature. The female connector comprises an opening, a collet finger, and an actuation element. The opening is adapted to guide the male connector along a first line of action as the male connector passes into the opening to be received within the female connector. The collet finger includes an engagement feature adapted to engage the coupling feature of the male end and displace along a second line of action generally normal to the first line of action. The actuation element is adapted to displace along a third line of action generally normal to the first and second lines of action in order to disengage the engagement feature from the coupling feature of the male end.

Abstract: Apparatus for performing an open wedge, high tibial osteotomy, the apparatus comprising: a wedge-shaped implant for disposition in a wedge-shaped opening created in the tibia, wherein the wedge-shaped implant comprises at least two keys, laterally offset from one another, for disposition in corresponding keyholes formed in the tibia adjacent to the wedge-shaped opening created in the tibia. Apparatus for performing an open wedge, high tibial osteotomy, the apparatus comprising: a wedge-shaped implant for disposition in a wedge-shaped opening created in the tibia, wherein the wedge-shaped implant comprises at least two keys, vertically offset from one another, for disposition in corresponding keyholes formed in the tibia adjacent to the wedge-shaped opening created in the tibia, and a shear rib, laterally offset from the at least two keys, for disposition in a corresponding shear rib keyhole formed in the tibia adjacent to the wedge-shaped opening created in the tibia.

Abstract: Apparatus for performing an open wedge, high tibial osteotomy, the apparatus comprising a wedge-shaped implant for disposition in a wedge-shaped opening created in the tibia, wherein the wedge-shaped implant comprises at least one key for disposition in at least one corresponding keyhole formed in the tibia adjacent to the wedge-shaped opening created in the tibia, wherein each of the at least one keys comprises an interior bore for receiving a fixation screw, at least one fixation screw for disposition in the interior bore of the at least one key, and further wherein the apparatus is configured so that when the at least one fixation screw is received in the interior bore, the at least one fixation screw terminates within the bore.

Abstract: Apparatus for performing an open wedge, high tibial osteotomy, the apparatus comprising: cutting apparatus for forming an osteotomy cut in the tibia, the cutting apparatus comprising: targeting apparatus for identifying a cutting plane through the tibia and a boundary line for terminating a cut made along the cutting plane, wherein the boundary line is located within the tibia, parallel to the anterior-posterior slope of the tibia and parallel to the sagittal plane of the patient.

Abstract: An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations, or modules, in which discrete aspects of the assay are performed on fluid samples contained in reaction receptacles. The analyzer includes stations for automatically preparing a specimen sample, incubating the sample at prescribed temperatures for prescribed periods, preforming an analyte isolation procedure, and ascertaining the presence of a target analyte. An automated receptacle transporting system moves the reaction receptacles from one station to the next.

Abstract: An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations, or modules, in which discrete aspects of the assay are performed on fluid samples contained in reaction receptacles. The analyzer includes stations for automatically preparing a specimen sample, incubating the sample at prescribed temperatures for prescribed periods, preforming an analyte isolation procedure, and ascertaining the presence of a target analyte. An automated receptacle transporting system moves the reaction receptacles from one station to the next.

Abstract: An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations, or modules, in which discrete aspects of the assay are performed on fluid samples contained in reaction receptacles. The analyzer includes stations for automatically preparing a specimen sample, incubating the sample at prescribed temperatures for prescribed periods, preforming an analyte isolation procedure, and ascertaining the presence of a target analyte. An automated receptacle transporting system moves the reaction receptacles from one station to the next.

Abstract: An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations, or modules, in which discrete aspects of the assay are performed on fluid samples contained in reaction receptacles. The analyzer includes stations for automatically preparing a specimen sample, incubating the sample at prescribed temperatures for prescribed periods, preforming an analyte isolation procedure, and ascertaining the presence of a target analyte. An automated receptacle transporting system moves the reaction receptacles from one station to the next.

Abstract: A faucet-mounted water filtration device includes a gate valve that is used to select between discharge options. The gate valve contains a thumb rest which is configured to allow manual valve actuation while supportedly engaging a user's thumb. First discharge option includes a conventional bottom discharge into a sink. A second discharge option exists as a water fountain that is formed as a compact, integral feature of the water filtration device. A flow indicator permits a user to check whether the filtration cartridge is working properly.