Patents by Inventor Ralph Dewey

Ralph Dewey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR GENERATING MALE STERILE PLANTS
    Publication number: 20240141311
    Abstract: Disclosed herein are recombinant meganucleases engineered to bind and cleave a recognition sequence in the mitochondrial DNA (mtDNA) of a eukaryotic cell, such as a plant cell. The disclosure further relates to the use of such recombinant meganucleases in methods for producing genetically-modified eukaryotic cells, and to a population of genetically-modified eukaryotic cells wherein the mtDNA has been having modified or edited.
    Type: Application
    Filed: April 22, 2022
    Publication date: May 2, 2024
    Applicant: North Carolina State University
    Inventors: Ralph Dewey, Derek Jantz, James Jefferson Smith, Ginger H. Tomberlin, John Morris, Anna Matthiadis, Wendy Shoop
  • Reducing tobacco specific nitrosamines through alteration of the nitrate assimilation pathway
    Patent number: 11666082
    Abstract: Provided are modified tobacco plants having reduced nitrate levels and tobacco products generated from the modified tobacco plants having reduced tobacco specific nitrosamines (TSNAs).
    Type: Grant
    Filed: September 23, 2015
    Date of Patent: June 6, 2023
    Assignees: Philip Morris Products S.A., North Carolina State University
    Inventors: Jianli Lu, Ramsey S. Lewis, Ralph Dewey, Lucien Bovet
  • REDUCING TOBACCO SPECIFIC NITROSAMINES THROUGH ALTERATION OF THE NITRATE ASSIMILATION PATHWAY
    Publication number: 20170303582
    Abstract: Provided are modified tobacco plants having reduced nitrate levels and tobacco products generated from the modified tobacco plants having reduced tobacco specific nitrosamines (TSNAs).
    Type: Application
    Filed: September 23, 2015
    Publication date: October 26, 2017
    Applicants: PHILIP MORRIS PRODUCTS S.A., NORTH CAROLINA STATE UNIVERSITY
    Inventors: Jianli Lu, Ramsey S. Lewis, Ralph Dewey, Lucien Bovet
  • Cytochrome P-450 constructs and method of producing herbicide-resistant transgenic plants
    Patent number: 6121512
    Abstract: DNA sequence encoding novel cytochrome P-450 molecules are provided. The use of DNA constructs containing such molecules to transform plants is described, as are transgenic plants exhibiting increased resistance to phenylurea herbicides. Methods of using such DNA constructs and transformed plants are provided.
    Type: Grant
    Filed: October 10, 1997
    Date of Patent: September 19, 2000
    Assignee: North Carolina State University
    Inventors: Balazs Siminszky, Ralph Dewey, Frederick Corbin
  • Maize cytoplasmic male sterility type T (cms-T) mitochondria DNA
    Patent number: 5660983
    Abstract: Reagents and test methods for rapidly and specifically testing maize plants for the presence of T-type cms are provided. The reagent includes a novel nucleic acid segment whose sequence is uniquely arranged in mitochondrial DNA of cms-T maize. The segment, designated TURF 2H3, was cloned and vectors comprising TURF 2H3 provided. Subclones having sequences specific to cms-T mitochondrial DNA and the DNA and deduced amino acid sequences of ORI3, which is unique to T-type cytoplasm, are also provided.
    Type: Grant
    Filed: November 23, 1994
    Date of Patent: August 26, 1997
    Assignees: Mycogen Plant Science, Inc., North Carolina State University
    Inventors: Charles S. Levings, III, Ralph Dewey