Abstract: A method of treating a patient suffering from peripheral vascular disease, peripheral neuropathies, or autonomic neuropathies by administering a cGMP PDE5 inhibitor such as sildenafil. The method is particularly applicable to patients suffering from diabetic foot ulcers, Raynaud's Phenomenon, CREST Syndrome, erythromatosis, rheumatoid diseases, diabetic retinopathies and onychiomycosis. According to the present invention, a cGMP PDE5 inhibitor may be administered as a prophylactic to patients predisposed to develop a peripheral vascular disease, peripheral neuropathy or autonomic neuropathy.

Abstract: This invention relates to the use of cyclic guanosine 3′, 5′-monophosphate phosphodiesterase type five (cGMP PDE5) inhibitors, including in particular the compound sildenafil, for the treatment of diabetic ulcers, particularly diabetic foot ulcers.

Abstract: A method of treating a patient suffering from peripheral vascular disease, peripheral neuropathies, or autonomic neuropathies by administering a cGMP PDE5 inhibitor such as sildenafil. The method is particularly applicable to patients suffering from diabetic foot ulcers, Raynaud's Phenomenon, CREST Syndrome, erythromatosis, rheumatoid diseases, diabetic retinopathies and onychiomycosis. According to the present invention, a cGMP PDE5 inhibitor may be administered as a prophylactic to patients predisposed to develop a peripheral vascular disease, peripheral neuropathy or autonomic neuropathy.

Abstract: A process for reducing the amount of catalyst required for coal hydrogenation-liquefaction reactions involving dry fed, short-residence coal reaction systems. Coal particles are mixed with dry catalyst material having a vapor pressure of 1 to 1000 mm Hg at reaction conditions. Catalysts having such high vapor pressure have demonstrated greatly improved ability to establish the required intimate contact for efficient catalysis when dry mixed and enable significant reduction of amounts of catalyst material required. In systems utilizing ZnCl.sub.2 as the catalyst material, reductions in percent weight concentration to the range of 1 to 2% are accomplished.The invention disclosed herein was developed in part under contract funding provided by the Energy Research and Development Administration of the United States Government.

Abstract: A system for protecting the personnel and the electrical equipment of power boats having non-metallic hulls, and for the cathodic protection of the hulls of the metal fittings of such boats when docked and supplied from a shore-based alternating current supply, in which circuit breakers are inserted in the hot leg and the neutral leg of the shore-based alternating current supply, and including a polarity alarm and a polarity light socket in which is inserted a polarity light tester as described in U.S. Pat. No. 3,383,588, and in which the negative lead of the battery ground, the equipment ground, and the neutral leg of the shore-based alternating current supply are connected electrically with both the ground plate and the bonding ground of the boat.