Patents by Inventor Ralph F. Hall

Ralph F. Hall has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds
    Patent number: 7700768
    Abstract: Novel substituted pyrimido[4,5-d]pyrimidin-2-one compounds and compositions for use in therapy as CSBP/p38 kinase inhibitors.
    Type: Grant
    Filed: October 11, 2007
    Date of Patent: April 20, 2010
    Assignee: GlaxoSmithKline LLC
    Inventors: Jerry L. Adams, Jeffrey C. Boehm, John J. Taggart, Ralph F. Hall
  • Tetrasubstituted pyrimidine compounds as chemical intermediates
    Patent number: 7629462
    Abstract: Novel substituted pyrimido[4,5-d]pyrimidin-2-one compounds and compositions for use in therapy as CSBP/p38 kinase inhibitors.
    Type: Grant
    Filed: December 20, 2006
    Date of Patent: December 8, 2009
    Assignee: SmithKline Beecham Corporation
    Inventors: Jerry L. Adams, Jeffrey C. Boehm, John J. Taggart, Ralph F. Hall
  • NOVEL COMPOUNDS
    Publication number: 20090239897
    Abstract: Novel substituted 1,5,7-trisubstituted-1,8-napthyridin-2(1H)-one compounds; 1,5,7 trisubstituted-1,6-napthyridine-2-(1H)-one compounds and 1,5,7-trisubstituted quinoline-2(1H)-one compounds, processes for the preparation thereof, the use thereof in treating CSBP/p38 kinase mediated diseases and pharmaceutical compositions for use in such therapy.
    Type: Application
    Filed: May 15, 2009
    Publication date: September 24, 2009
    Inventors: JEFFREY CHARLES BOEHM, JAMES FRANCIS CALLAHAN, RALPH F. HALL, XICHEN LIN, KATHERINE LOUISE WIDDOWSON
  • Compounds
    Patent number: 7550480
    Abstract: Novel substituted 1,5,7-trisubstituted-1,8-napthyridin-2(1H)-one compounds; 1,5,7 trisubstituted-1,6-napthyridine-2-(1H)-one compounds and 1,5,7-trisubstituted quinoline-2(1H)-one compounds, processes for the preparation thereof, the use thereof in treating CSBP/p38 kinase mediated diseases and pharmaceutical compositions for use in such therapy.
    Type: Grant
    Filed: February 13, 2004
    Date of Patent: June 23, 2009
    Assignee: SmithKline Beecham Corporation
    Inventors: Jeffrey Charles Boehm, James Francis Callahan, Ralph F. Hall, Xichen Lin, Katherine Louise Widdowson
  • Novel compounds
    Publication number: 20090048442
    Abstract: Novel substituted pyrimido[4,5-d]pyrimidin-2-one compounds and compositions for use in therapy as CSBP/p38 kinase inhibitors.
    Type: Application
    Filed: October 11, 2007
    Publication date: February 19, 2009
    Inventors: Jerry L. Adams, Jeffrey C. Boehm, John J. Taggart, Ralph F. Hall
  • Novel Substituted Imidazole Compounds
    Publication number: 20080114010
    Abstract: Novel 1,4,5-substituted imidazole compounds and compositions for use in therapy as CSBP/p38 kinase inhibitors.
    Type: Application
    Filed: November 21, 2007
    Publication date: May 15, 2008
    Inventors: Jerry L. Adams, Ralph F. Hall
  • Substituted imidazole compounds
    Patent number: 7301021
    Abstract: Novel 1,4,5-substituted imidazole compounds and compositions for use in therapy as CSBP/p38 kinase inhibitors.
    Type: Grant
    Filed: May 17, 2002
    Date of Patent: November 27, 2007
    Assignee: SmithKline Beecham Corporation
    Inventors: Jerry L. Adams, Ralph F. Hall
  • 1,5-disubstituted-3,4-dihydro-1h-pyrimido[4,5-d]pyrimidin-2-one compounds and their use in treating csbp/p38 kinase mediated diseases
    Patent number: 7235551
    Abstract: Novel substituted pyrimidol[4,5-d]pyrimidin-2-one compounds and compositions for use in therapy as CSBP/p38 kinase inhibitors.
    Type: Grant
    Filed: March 2, 2001
    Date of Patent: June 26, 2007
    Assignee: SmithKline Beecham Corporation
    Inventors: Jerry L. Adams, Jeffrey C. Boehm, John J. Taggart, Ralph F. Hall
  • Pyridin-4-YL or pyrimidin-4-YL substituted pyrazines
    Patent number: 6861417
    Abstract: Novel pyridin-4-yl or pyrimidin-4-yl substituted pyrazine compounds and compositions for use in therapy.
    Type: Grant
    Filed: April 14, 2003
    Date of Patent: March 1, 2005
    Assignee: SmithKline Beecham Corporation
    Inventors: Jerry L. Adams, Ralph F. Hall, Jeffrey C. Boehm
  • Pyridin-4-YL or pyrimidin-4-YL substituted pyrazines
    Publication number: 20040014973
    Abstract: Novel pyridin-4-yl or pyrimidin-4-yl substituted pyrazine compounds and compositions for use in therapy.
    Type: Application
    Filed: April 14, 2003
    Publication date: January 22, 2004
    Applicant: SmithKline Beecham Corporation
    Inventors: Jerry L. Adams, Ralph F. Hall, Jeffrey C. Boehm
  • Novel substituted imidazole compounds
    Publication number: 20030114452
    Abstract: Novel 1,4,5-substituted imidazole compounds and compositions for use in therapy as CSBP/p38 kinase inhibitors.
    Type: Application
    Filed: May 17, 2002
    Publication date: June 19, 2003
    Applicant: SmithKline Beecham Corporation
    Inventors: Jerry L. Adams, Ralph F. Hall
  • 1,5- disubstituted-3,4-dihydro-1h-pyrimido[4,5-d]pyrimidin-2-one compounds and their use in treating csbp/p38 kinase mediated diseases
    Publication number: 20030100756
    Abstract: Novel substituted pyrimido[4,5-d]pyrimidin-2-one compounds and compositions for use in therapy as CSBP/p38 kinase inhibitors.
    Type: Application
    Filed: August 28, 2002
    Publication date: May 29, 2003
    Inventors: Jerry L Adams, Jeffrey C Boehm, John J Taggart, Ralph F Hall
  • Substituted imidazole compounds
    Patent number: 6569871
    Abstract: Novel 1,4,5 substituted imidazole compounds and compositions for use in therapy as CSBP/p38 kinase inhibitors.
    Type: Grant
    Filed: December 15, 1999
    Date of Patent: May 27, 2003
    Assignee: SmithKline Beecham Corporation
    Inventors: Jerry L Adams, Ralph F Hall
  • Pyridin-4-yl or pyrimidin-4-yl substituted pyrazines
    Patent number: 6548503
    Abstract: The present invention is directed to novel pyridin-4-yl or pyrimidin-4-yl substituted pyrazine compounds and compositions for use in therapy.
    Type: Grant
    Filed: April 5, 2001
    Date of Patent: April 15, 2003
    Assignee: Smithkline Beecham Corporation
    Inventors: Jerry L. Adams, Ralph F. Hall, Jeffrey C. Boehm
  • Novel substituted imidazole compounds
    Publication number: 20030069243
    Abstract: Novel 1,4,5 substituted imidazole compounds and compositions for use in therapy as CSBP/p38 kinase inhibitors.
    Type: Application
    Filed: July 19, 2002
    Publication date: April 10, 2003
    Applicant: SmithKline Beecham Corporation
    Inventors: Jerry L. Adams, Ralph F. Hall
  • Substituted imidazole compounds
    Patent number: 6489325
    Abstract: The present invention relates to novel 1,4,5-substituted imidazole compounds and compositions for use in therapy as CSBP/p38 inhibitors.
    Type: Grant
    Filed: March 30, 2000
    Date of Patent: December 3, 2002
    Assignee: SmithKline Beecham Corporation
    Inventors: Jerry L. Adams, Ralph F. Hall
  • Anti-inflammatory compounds
    Patent number: 5545669
    Abstract: This invention relates to the novel compounds and pharmaceutical compositions of Formula (I).This invention also relates to a method of treating or reducing inflammation in a mammal in need thereof, which comprises administering to said mammal an effective amount of a compound or composition of Formula (I).
    Type: Grant
    Filed: June 2, 1994
    Date of Patent: August 13, 1996
    Inventors: Jerry L. Adams, Ralph F. Hall, Dennis Lee, Ruth J. Mayer, George L. Seibel
  • Anti-inflammatory compounds
    Patent number: 5447957
    Abstract: This invention relates to the novel compounds and pharmaceutical compositions of Formula (I).This invention also relates to a method of treating or reducing inflammation in a mammal in need thereof, which comprises administering to said mammal an effective amount of a compound or composition of Formula (I).
    Type: Grant
    Filed: June 2, 1994
    Date of Patent: September 5, 1995
    Assignee: SmithKline Beecham Corp.
    Inventors: Jerry L. Adams, Ralph F. Hall, George L. Seibel
  • Leukotriene antagonists
    Patent number: 5314918
    Abstract: This invention relates to alkanoic acid compounds having phenyl and heteroarylthio substituents which are useful as leukotriene antagonists, processes for the preparation thereof, and pharmaceutical compositions containing such compounds.This invention also relates to methods of treating diseases in which leukotrienes are a factor by administration of an effective amount of the above compounds or compositions.
    Type: Grant
    Filed: April 2, 1992
    Date of Patent: May 24, 1994
    Assignee: SmithKline Beecham Corporation
    Inventors: James S. Frazee, John G. Gleason, Ralph F. Hall
  • Ortho-substituted benzaldehydes
    Patent number: 5189226
    Abstract: This invention relates to certain 2-substituted benzaldehydes which are useful intermediates for preparing certain diacids which are useful as leukotriene antagonists.
    Type: Grant
    Filed: March 20, 1990
    Date of Patent: February 23, 1993
    Assignee: SmithKline Beecham Corporation
    Inventors: Ralph F. Hall, John F. Newton, Kathleen A. Phipps, Joanne Smallheer