Patents by Inventor Ralph Grassmann

Ralph Grassmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Selectable vectors for human T cells
    Patent number: 6025153
    Abstract: Selectable Herpesvirus saimiri vectors which have a selection gene inserted into a junction region of the L- and H-DNA are described. Vectors of this type are able persistently to infect human T cells and thus are suitable for the expression of foreign genes in human T cells. An additional advantage is that no infectious virus particles are produced during this.
    Type: Grant
    Filed: September 18, 1992
    Date of Patent: February 15, 2000
    Assignee: Hoechst AG
    Inventors: Bernhard Fleckenstein, Ralph Grassmann
  • H. saimiri-HTLV-X region vector
    Patent number: 5424197
    Abstract: An H. saimiri-HTLV-1 or 2 X region vector is disclosed. This vector can be used to establish continuous cell lines of difficult to grow cells, such as human T-cells. It can also be used to obtain certain cell products and in methods for screening new compounds.
    Type: Grant
    Filed: November 16, 1992
    Date of Patent: June 13, 1995
    Assignees: Dana Farber Cancer Institute, Behringwerke Aktiengesellschaft
    Inventors: William A. Haseltine, Kathleen McGuire, Marie-Christine Dokhelar, Ralph Grassmann, Bernard Fleckenstein, Ingrid Muller-Fleckenstein